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A2R650

- A2R650_ASPNC

UniProt

A2R650 - A2R650_ASPNC

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Protein
Submitted name:

Similarity: N-terminal half differs from all homologs

Gene
An15g06650
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

GO - Biological processi

  1. regulation of small GTPase mediated signal transduction Source: InterPro
  2. small GTPase mediated signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Guanine-nucleotide releasing factorSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Similarity: N-terminal half differs from all homologsImported
Gene namesi
ORF Names:An15g06650Imported
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006706: Chromosome 3R

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00012110.

Structurei

3D structure databases

ProteinModelPortaliA2R650.

Family & Domainsi

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation
Contains N-terminal Ras-GEF domain.SAAS annotations
Contains Ras-GEF domain.SAAS annotations

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

HOGENOMiHOG000167739.
OrthoDBiEOG78WM2F.

Family and domain databases

Gene3Di1.10.840.10. 1 hit.
InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2R650-1 [UniParc]FASTAAdd to Basket

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MFDSRVAEPL AVDTGSALAT KTNTYTATFE YPDEQVTTPT TGSRSRANSL     50
SFQQSSLTAN QSPTRRISSM KLTTDGRYTP SPEPPPALFV RAMYDYDADD 100
HTSLSFRRGD IIQVLNQLET GWWDGVIDNN LGELEEQGPQ THENEEVSAE 150
SGIGEEYEEE QDGDDVDSAG NPRDSQPILP IEGVGAPKEQ EEAAFWIPQA 200
TPDGRLFYFN TLTGYSTMEL PFENPAVNET GPYDRNNFLV PDQTRPPPEL 250
MARGFERDED DYDGSASEAE GESLMLTSRD SMSRRRQSYL DGVSPATSMD 300
SLHPPSATKS INDGKSSHQS LLTSHKFYDS ATSSNNSVSD NIHRPSVSSE 350
VPSHFVDDGF SVQLTWPLLV DNMRHAVEVY RQTLLNGDRS EYVRKAEDIS 400
DHLRMLLAAG SDTTDNHSGN PSVISTNKAL YPHFRDMMSK FSKLVLSSHI 450
AAADWPGPDS INKCLQEADG VMQGVYGYVE VARQQRGETI HRIVPGFVVG 500
SFSGGCWQNN GVSLSDSGPT SFLDHDANDS RAEPSVTLDA ALIDHIDILR 550
RSFVGSIRRL EERLTLNQKK IVTIKEHEEI ANAVSLAAIK VVEQFRPWMS 600
AVESINLAPL GTSFQNPQLV DFSLQKQRTY DAIADFVLSC QAVSAPLGDE 650
WAELRGNSLD DRLNAVRGVH RQLENYVSQI GFSLSLLLEQ VPEPSAFRAE 700
SRLGGENAGL KAIHSRSESQ AGVATESIGI PSSYSVENAS EKVRRNMDKA 750
QRFFGQAPPA AIPREPAMRE PVREPEETPW FLKTDHEGEV FYDTKNDSLN 800
LKCGTLAGLV EQLTRHDKLD ASFNNTFLLT YRSFTSAEEL FEMVTERFNI 850
QPPPGLNNDE MQMWIDRKQK PIRFRVVNIL KSWFENFWME PNDEPHMALL 900
QHVHAFTKDS IATTKTPGSP QLLAVIEQRL RGQDNTVKRL VPTQATAAPT 950
PIIPKNMKKL KFLDIDATEF ARQLTIIESR LYSKIRPTEC LNKTWQKKVG 1000
PDEPEPASNV KALILHSNQL TNWVAEMILN QSDVKKRVVV IKHFVNVADK 1050
CRALNNYSTL TSIISALGTA PIHRLGRTWA QVSGRTSTVL EQMRRLMAST 1100
KNFGEYRETL HLANPPCIPF FGVYLTDLTF IEDGIPSLTP SELINFNKRA 1150
KTAEVIRDIQ QYQNVPYLLQ PVPELQDYIL SNLQNAGDVH DMYDRSLEVE 1200
PREREDEKIA SARLASILAS PPGLLITTPV DLLFTRPDPE RPPITMLERR 1250
PMARSQFTPA TPCNFISQGA GPMSRQIPRS EPPFRRVSPL SLSAATWPIK 1300
HFTWTSCDIF TLILGLAWTI VISLIEYCGS RCTRSSSNVT LSPKDAPVTF 1350
SSHDHQSMDY WF 1362
Length:1,362
Mass (Da):152,300
Last modified:March 6, 2007 - v1
Checksum:iE35233AE9FC318FD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270349 Genomic DNA. Translation: CAK42617.1.

Genome annotation databases

EnsemblFungiiCADANGAT00012344; CADANGAP00012110; CADANGAG00012344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270349 Genomic DNA. Translation: CAK42617.1 .

3D structure databases

ProteinModelPortali A2R650.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 5061.CADANGAP00012110.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANGAT00012344 ; CADANGAP00012110 ; CADANGAG00012344 .

Phylogenomic databases

HOGENOMi HOG000167739.
OrthoDBi EOG78WM2F.

Family and domain databases

Gene3Di 1.10.840.10. 1 hit.
InterProi IPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RasGRF_CDC25.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48366. SSF48366. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
    Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
    , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
    Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CBS 513.88 / FGSC A1513.

Entry informationi

Entry nameiA2R650_ASPNC
AccessioniPrimary (citable) accession number: A2R650
Entry historyi
Integrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: June 11, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi