A2R650 (A2R650_ASPNC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Similarity: N-terminal half differs from all homologs EMBL CAK42617.1

Gene names

ORF Names:

An15g06650 EMBL CAK42617.1

Organism

Aspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]

Taxonomic identifier

425011 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus › Aspergillus niger

Protein attributes

Sequence length	1362 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities

Contains 1 N-terminal Ras-GEF domain. SAAS SAAS023578 Contains 1 Ras-GEF domain. SAAS SAAS023578 Contains 1 SH3 domain. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338
Molecular function	Guanine-nucleotide releasing factor SAAS SAAS023578
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro small GTPase mediated signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	guanyl-nucleotide exchange factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2R650 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: E35233AE9FC318FD	FASTA	1,362	152,300
	10 20 30 40 50 60 MFDSRVAEPL AVDTGSALAT KTNTYTATFE YPDEQVTTPT TGSRSRANSL SFQQSSLTAN 70 80 90 100 110 120 QSPTRRISSM KLTTDGRYTP SPEPPPALFV RAMYDYDADD HTSLSFRRGD IIQVLNQLET 130 140 150 160 170 180 GWWDGVIDNN LGELEEQGPQ THENEEVSAE SGIGEEYEEE QDGDDVDSAG NPRDSQPILP 190 200 210 220 230 240 IEGVGAPKEQ EEAAFWIPQA TPDGRLFYFN TLTGYSTMEL PFENPAVNET GPYDRNNFLV 250 260 270 280 290 300 PDQTRPPPEL MARGFERDED DYDGSASEAE GESLMLTSRD SMSRRRQSYL DGVSPATSMD 310 320 330 340 350 360 SLHPPSATKS INDGKSSHQS LLTSHKFYDS ATSSNNSVSD NIHRPSVSSE VPSHFVDDGF 370 380 390 400 410 420 SVQLTWPLLV DNMRHAVEVY RQTLLNGDRS EYVRKAEDIS DHLRMLLAAG SDTTDNHSGN 430 440 450 460 470 480 PSVISTNKAL YPHFRDMMSK FSKLVLSSHI AAADWPGPDS INKCLQEADG VMQGVYGYVE 490 500 510 520 530 540 VARQQRGETI HRIVPGFVVG SFSGGCWQNN GVSLSDSGPT SFLDHDANDS RAEPSVTLDA 550 560 570 580 590 600 ALIDHIDILR RSFVGSIRRL EERLTLNQKK IVTIKEHEEI ANAVSLAAIK VVEQFRPWMS 610 620 630 640 650 660 AVESINLAPL GTSFQNPQLV DFSLQKQRTY DAIADFVLSC QAVSAPLGDE WAELRGNSLD 670 680 690 700 710 720 DRLNAVRGVH RQLENYVSQI GFSLSLLLEQ VPEPSAFRAE SRLGGENAGL KAIHSRSESQ 730 740 750 760 770 780 AGVATESIGI PSSYSVENAS EKVRRNMDKA QRFFGQAPPA AIPREPAMRE PVREPEETPW 790 800 810 820 830 840 FLKTDHEGEV FYDTKNDSLN LKCGTLAGLV EQLTRHDKLD ASFNNTFLLT YRSFTSAEEL 850 860 870 880 890 900 FEMVTERFNI QPPPGLNNDE MQMWIDRKQK PIRFRVVNIL KSWFENFWME PNDEPHMALL 910 920 930 940 950 960 QHVHAFTKDS IATTKTPGSP QLLAVIEQRL RGQDNTVKRL VPTQATAAPT PIIPKNMKKL 970 980 990 1000 1010 1020 KFLDIDATEF ARQLTIIESR LYSKIRPTEC LNKTWQKKVG PDEPEPASNV KALILHSNQL 1030 1040 1050 1060 1070 1080 TNWVAEMILN QSDVKKRVVV IKHFVNVADK CRALNNYSTL TSIISALGTA PIHRLGRTWA 1090 1100 1110 1120 1130 1140 QVSGRTSTVL EQMRRLMAST KNFGEYRETL HLANPPCIPF FGVYLTDLTF IEDGIPSLTP 1150 1160 1170 1180 1190 1200 SELINFNKRA KTAEVIRDIQ QYQNVPYLLQ PVPELQDYIL SNLQNAGDVH DMYDRSLEVE 1210 1220 1230 1240 1250 1260 PREREDEKIA SARLASILAS PPGLLITTPV DLLFTRPDPE RPPITMLERR PMARSQFTPA 1270 1280 1290 1300 1310 1320 TPCNFISQGA GPMSRQIPRS EPPFRRVSPL SLSAATWPIK HFTWTSCDIF TLILGLAWTI 1330 1340 1350 1360 VISLIEYCGS RCTRSSSNVT LSPKDAPVTF SSHDHQSMDY WF

References

[1]

"Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88." Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M. , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H. Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CBS 513.88 / FGSC A1513.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM270349 Genomic DNA. Translation: CAK42617.1.
3D structure databases
ProteinModelPortal	A2R650.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	CADANGAT00012344; CADANGAP00012110; CADANGAG00012344.
Phylogenomic databases
HOGENOM	HOG000167739.
OrthoDB	EOG4TXG0X.
Family and domain databases
Gene3D	1.10.840.10. 1 hit.
InterPro	IPR000651. Ras-like_Gua-exchang_fac_N. IPR019804. Ras_G-nucl-exch_fac_CS. IPR008937. Ras_GEF. IPR023578. Ras_GEF_dom. IPR001895. RasGRF_CDC25. IPR001452. SH3_domain. [Graphical view]
PANTHER	PTHR23113. PTHR23113. 1 hit.
Pfam	PF00617. RasGEF. 1 hit. PF00618. RasGEF_N. 1 hit. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00452. SH3DOMAIN.
SMART	SM00147. RasGEF. 1 hit. SM00229. RasGEFN. 1 hit. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF48366. Ras_GEF. 1 hit. SSF50044. SH3. 1 hit.
PROSITE	PS00720. RASGEF. 1 hit. PS50009. RASGEF_CAT. 1 hit. PS50212. RASGEF_NTER. 1 hit. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2R650_ASPNC

Accession

Primary (citable) accession number: A2R650

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	March 6, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)