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A2R650

- A2R650_ASPNC

UniProt

A2R650 - A2R650_ASPNC

Protein
Submitted name:

Similarity: N-terminal half differs from all homologs

Gene

An15g06650

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. guanyl-nucleotide exchange factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of small GTPase mediated signal transduction Source: InterPro
    2. small GTPase mediated signal transduction Source: InterPro

    Keywords - Molecular functioni

    Guanine-nucleotide releasing factorSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Similarity: N-terminal half differs from all homologsImported
    Gene namesi
    ORF Names:An15g06650Imported
    OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)Imported
    Taxonomic identifieri425011 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006706: Chromosome 3R

    Subcellular locationi

    GO - Cellular componenti

    1. intracellular Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi5061.CADANGAP00012110.

    Structurei

    3D structure databases

    ProteinModelPortaliA2R650.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SH3 domain.UniRule annotation
    Contains N-terminal Ras-GEF domain.SAAS annotation
    Contains Ras-GEF domain.SAAS annotation

    Keywords - Domaini

    SH3 domainUniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000167739.
    OrthoDBiEOG78WM2F.

    Family and domain databases

    Gene3Di1.10.840.10. 1 hit.
    InterProiIPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF48366. SSF48366. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEiPS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2R650-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFDSRVAEPL AVDTGSALAT KTNTYTATFE YPDEQVTTPT TGSRSRANSL     50
    SFQQSSLTAN QSPTRRISSM KLTTDGRYTP SPEPPPALFV RAMYDYDADD 100
    HTSLSFRRGD IIQVLNQLET GWWDGVIDNN LGELEEQGPQ THENEEVSAE 150
    SGIGEEYEEE QDGDDVDSAG NPRDSQPILP IEGVGAPKEQ EEAAFWIPQA 200
    TPDGRLFYFN TLTGYSTMEL PFENPAVNET GPYDRNNFLV PDQTRPPPEL 250
    MARGFERDED DYDGSASEAE GESLMLTSRD SMSRRRQSYL DGVSPATSMD 300
    SLHPPSATKS INDGKSSHQS LLTSHKFYDS ATSSNNSVSD NIHRPSVSSE 350
    VPSHFVDDGF SVQLTWPLLV DNMRHAVEVY RQTLLNGDRS EYVRKAEDIS 400
    DHLRMLLAAG SDTTDNHSGN PSVISTNKAL YPHFRDMMSK FSKLVLSSHI 450
    AAADWPGPDS INKCLQEADG VMQGVYGYVE VARQQRGETI HRIVPGFVVG 500
    SFSGGCWQNN GVSLSDSGPT SFLDHDANDS RAEPSVTLDA ALIDHIDILR 550
    RSFVGSIRRL EERLTLNQKK IVTIKEHEEI ANAVSLAAIK VVEQFRPWMS 600
    AVESINLAPL GTSFQNPQLV DFSLQKQRTY DAIADFVLSC QAVSAPLGDE 650
    WAELRGNSLD DRLNAVRGVH RQLENYVSQI GFSLSLLLEQ VPEPSAFRAE 700
    SRLGGENAGL KAIHSRSESQ AGVATESIGI PSSYSVENAS EKVRRNMDKA 750
    QRFFGQAPPA AIPREPAMRE PVREPEETPW FLKTDHEGEV FYDTKNDSLN 800
    LKCGTLAGLV EQLTRHDKLD ASFNNTFLLT YRSFTSAEEL FEMVTERFNI 850
    QPPPGLNNDE MQMWIDRKQK PIRFRVVNIL KSWFENFWME PNDEPHMALL 900
    QHVHAFTKDS IATTKTPGSP QLLAVIEQRL RGQDNTVKRL VPTQATAAPT 950
    PIIPKNMKKL KFLDIDATEF ARQLTIIESR LYSKIRPTEC LNKTWQKKVG 1000
    PDEPEPASNV KALILHSNQL TNWVAEMILN QSDVKKRVVV IKHFVNVADK 1050
    CRALNNYSTL TSIISALGTA PIHRLGRTWA QVSGRTSTVL EQMRRLMAST 1100
    KNFGEYRETL HLANPPCIPF FGVYLTDLTF IEDGIPSLTP SELINFNKRA 1150
    KTAEVIRDIQ QYQNVPYLLQ PVPELQDYIL SNLQNAGDVH DMYDRSLEVE 1200
    PREREDEKIA SARLASILAS PPGLLITTPV DLLFTRPDPE RPPITMLERR 1250
    PMARSQFTPA TPCNFISQGA GPMSRQIPRS EPPFRRVSPL SLSAATWPIK 1300
    HFTWTSCDIF TLILGLAWTI VISLIEYCGS RCTRSSSNVT LSPKDAPVTF 1350
    SSHDHQSMDY WF 1362
    Length:1,362
    Mass (Da):152,300
    Last modified:March 6, 2007 - v1
    Checksum:iE35233AE9FC318FD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270349 Genomic DNA. Translation: CAK42617.1.

    Genome annotation databases

    EnsemblFungiiCADANGAT00012344; CADANGAP00012110; CADANGAG00012344.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270349 Genomic DNA. Translation: CAK42617.1 .

    3D structure databases

    ProteinModelPortali A2R650.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5061.CADANGAP00012110.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANGAT00012344 ; CADANGAP00012110 ; CADANGAG00012344 .

    Phylogenomic databases

    HOGENOMi HOG000167739.
    OrthoDBi EOG78WM2F.

    Family and domain databases

    Gene3Di 1.10.840.10. 1 hit.
    InterProi IPR000651. Ras-like_Gua-exchang_fac_N.
    IPR019804. Ras_G-nucl-exch_fac_CS.
    IPR023578. Ras_GEF_dom.
    IPR001895. RasGRF_CDC25.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00617. RasGEF. 1 hit.
    PF00618. RasGEF_N. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00147. RasGEF. 1 hit.
    SM00229. RasGEFN. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48366. SSF48366. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEi PS00720. RASGEF. 1 hit.
    PS50009. RASGEF_CAT. 1 hit.
    PS50212. RASGEF_NTER. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
      Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
      , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
      Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CBS 513.88 / FGSC A1513Imported.

    Entry informationi

    Entry nameiA2R650_ASPNC
    AccessioniPrimary (citable) accession number: A2R650
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 6, 2007
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3