Unreviewed, UniProtKB/TrEMBL A2R2D0 (A2R2D0_ASPNC)

Names and origin

Protein names

Submitted name:
Catalytic activity: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate. EMBL CAK41830.1
EC=6.2.1.4 EMBL CAK41830.1

Gene names

ORF Names:

An14g00310 EMBL CAK41830.1

Organism

Aspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]

Taxonomic identifier

425011 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	443 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the succinate/malate CoA ligase beta subunit family.

Ontologies

Keywords
Molecular function	Ligase RuleBase RU000678V1 EMBL CAK41830.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro succinate-CoA ligase (GDP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2R2D0-1 [UniParc]. Last modified March 6, 2007. Version 1. Checksum: 9F78B77090F4D3E7	FASTA	443	47,714
	10 20 30 40 50 60 MFKLARSKPV TAALRAATES SVQSRVAQQQ RNLSIHEYLS ANLLKSYGIG MPKGEVARSA 70 80 90 100 110 120 EEAEAVAKSL GNDDMVIKAQ VLAGGRGKGT FDNGLKGGVR VIYSPTEAKM FASQMIGQKL 130 140 150 160 170 180 ITKQTGAAGR LCNSVYICER KFARREFYLA VLMDRASQSP VIVASSQGGM DIEAVAKENP 190 200 210 220 230 240 EAIITTPIDI KVGVTDAIAH KIVTELGFSE QCVEEAKDTI QKLYKVFMEK DATQIEINPL 250 260 270 280 290 300 SETSDHKVMA MDAKLGFDDN AEFRQKEVFS WRDTTQEDAD EVKAAEHGLN FIKLDGDIGC 310 320 330 340 350 360 LVNGAGLAMA TMDIIKLNGG APANFLDVGG GATPAAIKSA FELITSDPKV TAIFVNIFGG 370 380 390 400 410 420 IVRCDAIAQG LINVVQEMGL RTPIVARLQG TNMEQAHKLI NESGLKIFSI EDLQSAAEKS 430 440 VQFSKVVKMA REIDVGVEFT LGI

References

[1]

"Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88." Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M. , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H. Nat. Biotechnol. 25:221-231(2007) [PubMed: 17259976] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	AM270309 Genomic DNA. Translation: CAK41830.1.
RefSeq	XP_001400660.1.
3D structure databases
SMR	A2R2D0. Positions 33-422.
ModBase	Search...
Genome annotation databases
GeneID	4986880.
KEGG	ang:An14g00310.
Phylogenomic databases
HOGENOM	HBG315432.
OrthoDB	EOG95MPP2.
Family and domain databases
HAMAP	MF_00558. Succ_CoA_beta. [Tree]
InterPro	IPR011761. ATP-grasp. IPR013650. ATP-grasp_succ-CoA_synth-type. IPR013816. ATP_grasp_subdomain_2. IPR005811. CoA_ligase. IPR017866. Succ-CoA_synthase_bsu_CS. IPR005809. Succ_CoA_synthase_bsu. IPR016102. Succinyl-CoA_synth-like. [Graphical view]
Gene3D	G3DSA:3.30.470.20. ATP_grasp_subdomain_2. 1 hit. G3DSA:3.40.50.261. Succinyl-CoA_synth-like. 1 hit.
PANTHER	PTHR11815. CoA_lig_beta. 1 hit.
Pfam	PF08442. ATP-grasp_2. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view]
SUPFAM	SSF52210. CoA_ligase. 1 hit.
TIGRFAMs	TIGR01016. sucCoAbeta. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. PS01217. SUCCINYL_COA_LIG_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2R2D0_ASPNC

Accession

Primary (citable) accession number: A2R2D0

Entry history

Integrated into UniProtKB/TrEMBL:	March 6, 2007
Last sequence update:	March 6, 2007
Last modified:	March 2, 2010
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)