Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Histone-lysine N-methyltransferase

Gene

An12g03880

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N6-methyl-L-lysine-[histone].PROSITE-ProRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotation, Transferase
LigandS-adenosyl-L-methioninePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferasePROSITE-ProRule annotation (EC:2.1.1.43PROSITE-ProRule annotation)
Gene namesi
ORF Names:An12g03880Imported
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)Imported
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 3L

Structurei

3D structure databases

ProteinModelPortaliA2QZ73.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 234SETInterPro annotationAdd BLAST115

Sequence similaritiesi

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar4-20 subfamily.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000214006.
KOiK11429.
OrthoDBiEOG092C4LF0.

Family and domain databases

InterProiView protein in InterPro
IPR025783. Hist-Lys_N-MeTrfase_SET9.
IPR001214. SET_dom.
PfamiView protein in Pfam
PF00856. SET. 1 hit.
SMARTiView protein in SMART
SM00317. SET. 1 hit.
PROSITEiView protein in PROSITE
PS51567. SAM_MT43_SUVAR420_1. 1 hit.
PS50280. SET. 1 hit.

Sequencei

Sequence statusi: Complete.

A2QZ73-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPVSKAKSSP SDDRRDRLTL AKLASYDDVA TDALVDRAYF WTNTRKNRTK
60 70 80 90 100
YNPARGIKDD DVASTLLHDV IVNKDAAKAE AKLLSMPGLK KYLAKLPTDR
110 120 130 140 150
EKEWFRRHLR KYIQMYLPDS PFEVTTTNRY TVTEHEAAIC ARKFIKQGQE
160 170 180 190 200
IKYLSGTLVP MTKEEEQDLD LKRKDFSIVM SSRRKTPSFF LGPARFANHD
210 220 230 240 250
CNANGRLVTR GMEGMQVVAI RNIHIGEEIT VSYGEDYFGI DNCECLCLTC
260 270 280 290 300
ERAVRNGWAP QLDSDQESPA STPAYDEPAL SEALLSPNKR KHVPDTDSES
310 320 330 340 350
SPSSTPRKRT KFTRQSSKLR SEVVFSDLTP SIESSTVQPA GAGFSSQALS
360 370 380 390 400
VPHAAAAETA SDHVIDNKSD IHTESTVQST ATTTADPDSP GSLDDSHRSS
410 420 430 440 450
TSTAATSVCD NPVQIKIEEV TETTVQAPIL TVEGRLDLST GSADPERRIL
460 470 480 490 500
GVDNDALSDL SDSLELDEKL GTVVKKSRKS RSKEVVPSVE VEPPRARVPG
510 520 530 540 550
DYTKTSKLLA QAYDRWVDCR TCNAWFVQQD SYLTRRECPR CERHSKLYGF
560 570 580 590 600
QWPKTDREGP ADDEERVMDH RTVHRFLYPE EEALISRKDR GVSFGITPTP
610 620 630
ELSEPHADTE DSEAGEDRRN TRASRRRTRS LRMTM
Length:635
Mass (Da):71,179
Last modified:March 6, 2007 - v1
Checksum:iD64308F15C696F7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270267 Genomic DNA. Translation: CAK46158.1.
RefSeqiXP_001395462.1. XM_001395425.2.

Genome annotation databases

EnsemblFungiiCAK46158; CAK46158; An12g03880.
GeneIDi4985736.
KEGGiang:ANI_1_476104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270267 Genomic DNA. Translation: CAK46158.1.
RefSeqiXP_001395462.1. XM_001395425.2.

3D structure databases

ProteinModelPortaliA2QZ73.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAK46158; CAK46158; An12g03880.
GeneIDi4985736.
KEGGiang:ANI_1_476104.

Phylogenomic databases

HOGENOMiHOG000214006.
KOiK11429.
OrthoDBiEOG092C4LF0.

Family and domain databases

InterProiView protein in InterPro
IPR025783. Hist-Lys_N-MeTrfase_SET9.
IPR001214. SET_dom.
PfamiView protein in Pfam
PF00856. SET. 1 hit.
SMARTiView protein in SMART
SM00317. SET. 1 hit.
PROSITEiView protein in PROSITE
PS51567. SAM_MT43_SUVAR420_1. 1 hit.
PS50280. SET. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiA2QZ73_ASPNC
AccessioniPrimary (citable) accession number: A2QZ73
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: June 7, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.