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Protein

Sterol 3-beta-glucosyltransferase

Gene

atg26

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May be involved in decane metabolism and autophagy. Involved in the biosynthesis of sterol glucoside (By similarity).By similarity

Catalytic activityi

UDP-glucose + a sterol = UDP + a sterol 3-beta-D-glucoside.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Autophagy, Lipid biosynthesis, Lipid metabolism, Protein transport, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transport

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
Sterol 3-beta-glucosyltransferase (EC:2.4.1.173)
Alternative name(s):
Autophagy-related protein 26
Gene namesi
Name:atg26
ORF Names:An07g06610
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 4L

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13711371Sterol 3-beta-glucosyltransferasePRO_0000318041Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA2QNQ5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini241 – 30161GRAM 1Add
BLAST
Domaini292 – 391100PHPROSITE-ProRule annotationAdd
BLAST
Domaini717 – 78367GRAM 2Add
BLAST

Sequence similaritiesi

Belongs to the glycosyltransferase 28 family.Curated
Contains 2 GRAM domains.Curated
Contains 1 PH domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

KOiK05841.
OrthoDBiEOG092C09PF.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR004276. GlycoTrans_28_N.
IPR004182. GRAM.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF03033. Glyco_transf_28. 1 hit.
PF02893. GRAM. 2 hits.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00568. GRAM. 2 hits.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2QNQ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPFIDDAKR RVDRRLSASR QSISNSRMFA SVLPERLRND NDDDDDSQVD
60 70 80 90 100
FSAPPGGMGP REGHMQYMHQ SIFGMIAAVG SRSGFHARYD ESSDSDGEDE
110 120 130 140 150
SRARKDAENL SATAGALPKR SGNESPRLSP KPQSPTPERG RRHRRTISDH
160 170 180 190 200
KLLRPFKLNS KQNKGQEPAV QSEPQTGDEM SRASTPKRPR SVTPRAAPVL
210 220 230 240 250
SRMVEARALL DTEDSTKGAP STTEEIRDEG PTQKSASALS LRLKEMFGFE
260 270 280 290 300
APEKVLVEYA CSFLQSMLLQ GYMYVTEGHV CFYAYLPRKS TVAIKSGYVY
310 320 330 340 350
KRGRKNPKYN RYWFSLKGDV LSYYADPSKL YFPSGHVDLR YGISASLAEP
360 370 380 390 400
KDKGREVKDF QVTTDQRTYY FRADSSSSAK EWVKALQKVI FRTHNDKGSV
410 420 430 440 450
KISFPIENII DIEESPMVDF AETFKIRVVE SEETYAIDEY YFTSFNYGQD
460 470 480 490 500
AFNFLKGLVA DTPMKRSQQT LSPQPEQTSR SRRTRGSQNR WSITSATSQS
510 520 530 540 550
RGIGKSGNRR RSASTGQFSF GHDALSMSPP MRQQDSSLSF GNSFEQATEA
560 570 580 590 600
SGILQSMTDT TESASQILNR SDVFQSPTIR TMRRGPSGAE KTVRRHSDET
610 620 630 640 650
ARSVHTTRNG PEIQYAVSES DRDTQTPSGL HPSTPALNEL VRAGVYPLQR
660 670 680 690 700
AAGFAEYLKT RSKQMSNLLA SESMGYLEKV SGMWAGGGKH YGESENILPD
710 720 730 740 750
DQAVDPEDLE AGCKDGDRFR EHFALPPSEK LQASYFAWLH RMIPLYGKIY
760 770 780 790 800
ISQKKLCFRS LMPGTRTKMI LPLKDVENVD KEKGFNFGRH GLVVVIRGHE
810 820 830 840 850
ELFFEFGTAD TRDDCAVTLH KGLESTKFLM ASGLLAECEE KDESESATAE
860 870 880 890 900
HRLLQEARLD ITGMHSSRSA MAASNELHPI FDDPRASIIN FKPTESLRIT
910 920 930 940 950
CLTIGSRGDV QPYIALCKGL LAEGHRPKIA THAEFEPWVR KHGIDFALVD
960 970 980 990 1000
GDPAELMRIC VENGMFTYSF FKEATAKFRG WIDDLLSSAW KACQDTDLLI
1010 1020 1030 1040 1050
ESPSAMAGIH IAEALRIPYF RAFTMPWSRT RAYPHAFAVP EHKMGGAYNY
1060 1070 1080 1090 1100
ITYVMFDNVF WKSVAGQVNR WRKKELGLKA TGLDKMQPNK VPFLYNYSPT
1110 1120 1130 1140 1150
VVPPPLDYPD WIRITGYWFL SEGSDWTPPA ELVDFIQRAR KDEKKVVYIG
1160 1170 1180 1190 1200
FGSIVVSDPS ALTRTVIESV QKADVRCILS KGWSDRLGDP ASAKSEVPLP
1210 1220 1230 1240 1250
PEIYQIQSAP HDWLFSHIDA AAHHGGAGTT GASLRAGVPT IVKPFFGDQF
1260 1270 1280 1290 1300
FFGTRVEDLG VGICLKKLNV TMFSRALWEA THDERMIVKA HKLGAQIRSE
1310 1320 1330 1340 1350
DGVDTAIQAI YRDLEYAKTL AQARSNVSST PFSPTPSAKT VAEQEADEDV
1360 1370
PEEEWTIVED DTELEMRPTV A
Length:1,371
Mass (Da):153,536
Last modified:February 5, 2008 - v2
Checksum:i1E8C4CF3CEFA773F
GO

Sequence cautioni

The sequence CAK39507 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAK39507 differs from that shown. Reason: Erroneous gene model prediction. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270135 Genomic DNA. Translation: CAK39507.1. Sequence problems.
RefSeqiXP_001391739.2. XM_001391702.2.

Genome annotation databases

GeneIDi4981929.
KEGGiang:ANI_1_830064.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270135 Genomic DNA. Translation: CAK39507.1. Sequence problems.
RefSeqiXP_001391739.2. XM_001391702.2.

3D structure databases

ProteinModelPortaliA2QNQ5.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4981929.
KEGGiang:ANI_1_830064.

Phylogenomic databases

KOiK05841.
OrthoDBiEOG092C09PF.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR004276. GlycoTrans_28_N.
IPR004182. GRAM.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
IPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF03033. Glyco_transf_28. 1 hit.
PF02893. GRAM. 2 hits.
PF00169. PH. 1 hit.
[Graphical view]
SMARTiSM00568. GRAM. 2 hits.
SM00233. PH. 1 hit.
[Graphical view]
SUPFAMiSSF50729. SSF50729. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATG26_ASPNC
AccessioniPrimary (citable) accession number: A2QNQ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 5, 2008
Last modified: September 7, 2016
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.