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A2QMY6 (SODC_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Cu-Zn]

EC=1.15.1.1
Gene names
Name:sodC
ORF Names:An07g03770
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length154 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity. UniProtKB P00442

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2. UniProtKB P00442

Cofactor

Binds 1 copper ion per subunit By similarity. UniProtKB P00442

Binds 1 zinc ion per subunit By similarity. UniProtKB P00442

Subunit structure

Homodimer By similarity. UniProtKB P00442

Subcellular location

Cytoplasm By similarity UniProtKB P00442.

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandCopper
Metal-binding
Zinc
   Molecular functionAntioxidant
Oxidoreductase
   PTMDisulfide bond
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processsuperoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

intracellular

Inferred from direct assay PubMed 20406453. Source: ASPGD

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed By similarity UniProtKB P00442
Chain2 – 154153Superoxide dismutase [Cu-Zn] UniProtKB P00442
PRO_0000355100

Sites

Metal binding471Copper; catalytic By similarity UniProtKB P00442
Metal binding491Copper; catalytic By similarity UniProtKB P00442
Metal binding641Copper; catalytic By similarity UniProtKB P00442
Metal binding641Zinc; structural By similarity
Metal binding721Zinc; structural By similarity UniProtKB P00442
Metal binding811Zinc; structural By similarity UniProtKB P00442
Metal binding841Zinc; structural By similarity UniProtKB P00442
Metal binding1211Copper; catalytic By similarity UniProtKB P00442

Amino acid modifications

Disulfide bond58 ↔ 147 By similarity UniProtKB P00442

Sequences

Sequence LengthMass (Da)Tools
A2QMY6 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: C8679562F6FB52AF

FASTA15415,960
        10         20         30         40         50         60 
MVKAVAVIRG DSKVSGTVTF EQANENTPTT ISWNITGHDA NAERGFHVHQ FGDNTNGCTS 

        70         80         90        100        110        120 
AGPHFNPFGK THGAPEDDER HVGDLGNFKT DAEGNAVGSK QDKLVKLIGA ESVLGRTLVV 

       130        140        150 
HAGTDDLGRG GNEESKKTGN AGPRPACGVI GIAA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270128 Genomic DNA. Translation: CAK48127.1.
RefSeqXP_001391459.1. XM_001391422.2.

3D structure databases

ProteinModelPortalA2QMY6.
SMRA2QMY6. Positions 2-152.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5061.CADANGAP00005537.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00005648; CADANGAP00005537; CADANGAG00005648.
GeneID4981643.
KEGGang:ANI_1_470064.

Phylogenomic databases

HOGENOMHOG000263447.
KOK04565.
OrthoDBEOG7HQNMC.

Family and domain databases

Gene3D2.60.40.200. 1 hit.
InterProIPR024134. SOD_Cu/Zn_/chaperone.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERPTHR10003. PTHR10003. 1 hit.
PfamPF00080. Sod_Cu. 1 hit.
[Graphical view]
PRINTSPR00068. CUZNDISMTASE.
SUPFAMSSF49329. SSF49329. 1 hit.
PROSITEPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSODC_ASPNC
AccessionPrimary (citable) accession number: A2QMY6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 25, 2008
Last sequence update: March 6, 2007
Last modified: November 13, 2013
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families