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A2QJF9 (PRTT_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Transcriptional activator of proteases prtT
Alternative name(s):
Zn(2)-C6 zinc finger-containing protein prtT
Gene names
Name:prtT
ORF Names:An04g06940
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length623 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Transcription factor required for protein utilization and degradation. Regulates transcription of major secreted proteases. Ref.2

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the prtT family.

Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 623623Transcriptional activator of proteases prtT
PRO_0000407033

Regions

DNA binding50 – 7930Zn(2)-C6 fungal-type

Sequences

Sequence LengthMass (Da)Tools
A2QJF9 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: CE107CEBC798514E

FASTA62370,224
        10         20         30         40         50         60 
MTRTVDEIKY ETPSSWEHKS LDVAEDGRRL APHSDTARPK GRIRRSMTAC HTCRKLKTRC 

        70         80         90        100        110        120 
DLDPRGHACR RCLSLRIDCK LPETTDRFQD SAAMWPDATS AIPSIEERLT SLERCMREMT 

       130        140        150        160        170        180 
GMMRQMLDHS PGFANASVPH LTKSIITDEN ASMEGSPSSP FLPKPVRLIQ DLQSDFFGEA 

       190        200        210        220        230        240 
ETSPVDSPLS SDGNAKGAID SKLSLKLLQT FVDHFGACVS IYNLSDIHND MKAPDSLLYN 

       250        260        270        280        290        300 
TACLLASRYV PGIPTSTVHA IYLQVRHAVV NILWEKPPLK YETLQALALL CLWPATAQKE 

       310        320        330        340        350        360 
PPMDSWLLSG ISINHAIIAL DFLNYAPSEV MVDNETAAQL RLWNTYCLTQ LHFAVGNARP 

       370        380        390        400        410        420 
FHIQQRYLDH CPRILEHPAA TLEDARVVAE IQLYLMTLRL QSNSSRMRLA DLDYEEIERW 

       430        440        450        460        470        480 
KREWAHLFSG ESSTLELSLW FCQTLLHRTA MRLQPRSDRL ASEVLQTSRL IISRFLQIRY 

       490        500        510        520        530        540 
STALSLVDQV YFIVGYAALN LCDFNLMDPL IEQVQMFLLH LSPNEDHIAY RFSCMVAEFK 

       550        560        570        580        590        600 
RRCGSAECND PSSTVKGSPL SSYGDSRKMS MGQAPFMPPL MDGMIEGYGF EQLMPEVMPS 

       610        620 
SFPDGILNGM PVTGLAAYRS ATL 

« Hide

References

« Hide 'large scale' references
[1]"Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M. expand/collapse author list , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CBS 513.88 / FGSC A1513.
[2]"Characterization of the Aspergillus niger prtT, a unique regulator of extracellular protease encoding genes."
Punt P.J., Schuren F.H., Lehmbeck J., Christensen T., Hjort C., van den Hondel C.A.
Fungal Genet. Biol. 45:1591-1599(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270080 Genomic DNA. Translation: CAK44694.1.
RefSeqXP_001402055.1. XM_001402018.2.

3D structure databases

ProteinModelPortalA2QJF9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5061.CADANGAP00004310.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00004405; CADANGAP00004310; CADANGAG00004405.
GeneID4991098.
KEGGang:ANI_1_1102184.

Phylogenomic databases

eggNOGNOG81463.
HOGENOMHOG000190417.
OrthoDBEOG75MW59.

Family and domain databases

Gene3D4.10.240.10. 1 hit.
InterProIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamPF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMSSF57701. SSF57701. 1 hit.
PROSITEPS00463. ZN2_CY6_FUNGAL_1. 1 hit.
PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePRTT_ASPNC
AccessionPrimary (citable) accession number: A2QJF9
Entry history
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families