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A2QFV9

- AXHA_ASPNC

UniProt

A2QFV9 - AXHA_ASPNC

Protein

Probable alpha-L-arabinofuranosidase axhA

Gene

axhA

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
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    Functioni

    Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan By similarity.By similarity

    Catalytic activityi

    Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.

    GO - Molecular functioni

    1. alpha-L-arabinofuranosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. L-arabinose metabolic process Source: InterPro
    2. xylan catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

    Protein family/group databases

    CAZyiGH62. Glycoside Hydrolase Family 62.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable alpha-L-arabinofuranosidase axhA (EC:3.2.1.55)
    Alternative name(s):
    Arabinoxylan arabinofuranohydrolase axhA
    Gene namesi
    Name:axhA
    ORF Names:An03g00960
    OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
    Taxonomic identifieri425011 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006706: Chromosome 6R

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2626Sequence AnalysisAdd
    BLAST
    Chaini27 – 332306Probable alpha-L-arabinofuranosidase axhAPRO_5000219727Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5061.CADANGAP00003042.

    Structurei

    3D structure databases

    ProteinModelPortaliA2QFV9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 62 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    HOGENOMiHOG000164911.
    KOiK01209.
    OrthoDBiEOG74J9JT.

    Family and domain databases

    InterProiIPR005193. GH62_arabinosidase.
    IPR023296. Glyco_hydro_beta-prop.
    [Graphical view]
    PfamiPF03664. Glyco_hydro_62. 1 hit.
    [Graphical view]
    SUPFAMiSSF75005. SSF75005. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    A2QFV9-1 [UniParc]FASTAAdd to Basket

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    MKFLKAKGSL LSSGIYLIAL APFVNAKCAL PSTYSWTSTD ALATPKSGWT    50
    ALKDFTDVVS NGKHIVYAST TDTQGNYGSM GFGAFSDWSD MASASQTATS 100
    FSAVAPTLFY FQPKSIWVLA YQWGSSTFTY RTSQDPTNVN GWSSEQALFT 150
    GKISGSSTGA IDQTVIGDDT NMYLFFAGDN GKIYRSSMSI NDFPGSFGSQ 200
    YEEILSGATN DLFEAVQVYT VDGGEGDSKY LMIVEAIGST GHRYFRSFTA 250
    SSLGGEWTAQ AASEDQPFAG KANSGATWTD DISHGDLVRN NPDQTMTVDP 300
    CNLQLLYQGH DPNSNSDYNL LPWKPGVLTL KQ 332
    Length:332
    Mass (Da):35,837
    Last modified:March 6, 2007 - v1
    Checksum:iF6EEE44EB8C43FEB
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270045 Genomic DNA. Translation: CAK38069.1.
    RefSeqiXP_001389998.1. XM_001389961.2.

    Genome annotation databases

    EnsemblFungiiCADANGAT00003121; CADANGAP00003042; CADANGAG00003121.
    GeneIDi4980084.
    KEGGiang:ANI_1_108034.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270045 Genomic DNA. Translation: CAK38069.1 .
    RefSeqi XP_001389998.1. XM_001389961.2.

    3D structure databases

    ProteinModelPortali A2QFV9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5061.CADANGAP00003042.

    Protein family/group databases

    CAZyi GH62. Glycoside Hydrolase Family 62.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANGAT00003121 ; CADANGAP00003042 ; CADANGAG00003121 .
    GeneIDi 4980084.
    KEGGi ang:ANI_1_108034.

    Phylogenomic databases

    HOGENOMi HOG000164911.
    KOi K01209.
    OrthoDBi EOG74J9JT.

    Family and domain databases

    InterProi IPR005193. GH62_arabinosidase.
    IPR023296. Glyco_hydro_beta-prop.
    [Graphical view ]
    Pfami PF03664. Glyco_hydro_62. 1 hit.
    [Graphical view ]
    SUPFAMi SSF75005. SSF75005. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
      Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
      , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
      Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CBS 513.88 / FGSC A1513.

    Entry informationi

    Entry nameiAXHA_ASPNC
    AccessioniPrimary (citable) accession number: A2QFV9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 20, 2010
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3