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Protein

Probable alpha-L-arabinofuranosidase axhA

Gene

axhA

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Alpha-L-arabinofuranosidase involved in the hydrolysis of xylan, a major structural heterogeneous polysaccharide found in plant biomass representing the second most abundant polysaccharide in the biosphere, after cellulose. Releases L-arabinose from arabinoxylan (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Protein family/group databases

CAZyiGH62. Glycoside Hydrolase Family 62.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-L-arabinofuranosidase axhA (EC:3.2.1.55)
Alternative name(s):
Arabinoxylan arabinofuranohydrolase axhA
Gene namesi
Name:axhA
ORF Names:An03g00960
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 6R

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500021972727 – 332Probable alpha-L-arabinofuranosidase axhAAdd BLAST306

Structurei

3D structure databases

ProteinModelPortaliA2QFV9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 62 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000164911.
KOiK01209.
OrthoDBiEOG092C438U.

Family and domain databases

InterProiIPR005193. GH62_arabinosidase.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PfamiPF03664. Glyco_hydro_62. 1 hit.
[Graphical view]
SUPFAMiSSF75005. SSF75005. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A2QFV9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKFLKAKGSL LSSGIYLIAL APFVNAKCAL PSTYSWTSTD ALATPKSGWT
60 70 80 90 100
ALKDFTDVVS NGKHIVYAST TDTQGNYGSM GFGAFSDWSD MASASQTATS
110 120 130 140 150
FSAVAPTLFY FQPKSIWVLA YQWGSSTFTY RTSQDPTNVN GWSSEQALFT
160 170 180 190 200
GKISGSSTGA IDQTVIGDDT NMYLFFAGDN GKIYRSSMSI NDFPGSFGSQ
210 220 230 240 250
YEEILSGATN DLFEAVQVYT VDGGEGDSKY LMIVEAIGST GHRYFRSFTA
260 270 280 290 300
SSLGGEWTAQ AASEDQPFAG KANSGATWTD DISHGDLVRN NPDQTMTVDP
310 320 330
CNLQLLYQGH DPNSNSDYNL LPWKPGVLTL KQ
Length:332
Mass (Da):35,837
Last modified:March 6, 2007 - v1
Checksum:iF6EEE44EB8C43FEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270045 Genomic DNA. Translation: CAK38069.1.
RefSeqiXP_001389998.1. XM_001389961.2.

Genome annotation databases

EnsemblFungiiCAK38069; CAK38069; An03g00960.
GeneIDi4980084.
KEGGiang:ANI_1_108034.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270045 Genomic DNA. Translation: CAK38069.1.
RefSeqiXP_001389998.1. XM_001389961.2.

3D structure databases

ProteinModelPortaliA2QFV9.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH62. Glycoside Hydrolase Family 62.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAK38069; CAK38069; An03g00960.
GeneIDi4980084.
KEGGiang:ANI_1_108034.

Phylogenomic databases

HOGENOMiHOG000164911.
KOiK01209.
OrthoDBiEOG092C438U.

Family and domain databases

InterProiIPR005193. GH62_arabinosidase.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PfamiPF03664. Glyco_hydro_62. 1 hit.
[Graphical view]
SUPFAMiSSF75005. SSF75005. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiAXHA_ASPNC
AccessioniPrimary (citable) accession number: A2QFV9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: March 6, 2007
Last modified: November 30, 2016
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.