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A2QFH1 (RIFK_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Riboflavin kinase

EC=2.7.1.26
Alternative name(s):
Flavin mononucleotide kinase 1
Gene names
Name:fmn1
ORF Names:An02g14530
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length214 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme By similarity.

Catalytic activity

ATP + riboflavin = ADP + FMN.

Cofactor

Zinc or magnesium By similarity.

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

Sequence similarities

Belongs to the flavokinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 214214Riboflavin kinase
PRO_0000301835

Sites

Active site1011Nucleophile By similarity
Metal binding441Magnesium or zinc By similarity

Sequences

Sequence LengthMass (Da)Tools
A2QFH1 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: D979FBF22D21DCEF

FASTA21423,277
        10         20         30         40         50         60 
MRPDRPRDPV TGPDEGPESP YPIRMSGPVI KGFGRGSKEL GIPTANIPAD ELSQHPELSV 

        70         80         90        100        110        120 
GVYYGVVALD PARFSTGETV LPAVLSIGYN PFYKNESKSI EIHIMPPLSA PSPTATTSTD 

       130        140        150        160        170        180 
GQVTFHKLPD FYGTPLNLLI LGYIRPEYDY ISSEALIEDI RVDCEVARRS LQRPAYRCYL 

       190        200        210 
DARAVEDPAC GGDDCGIVVD AIDGGAMRGM RFCI 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270040 Genomic DNA. Translation: CAK48882.1.

3D structure databases

ProteinModelPortalA2QFH1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5061.CADANGAP00002904.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00002978; CADANGAP00002904; CADANGAG00002978.

Phylogenomic databases

eggNOGCOG0196.
HOGENOMHOG000260803.
OrthoDBEOG7K3V05.

Enzyme and pathway databases

UniPathwayUPA00276; UER00406.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
InterProIPR023468. Riboflavin_kinase.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PANTHERPTHR22749. PTHR22749. 1 hit.
PfamPF01687. Flavokinase. 1 hit.
[Graphical view]
SMARTSM00904. Flavokinase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIFK_ASPNC
AccessionPrimary (citable) accession number: A2QFH1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: March 6, 2007
Last modified: January 22, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways