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Protein

Transcription activator of gluconeogenesis acuK

Gene

acuK

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi71 – 99Zn(2)-C6 fungal-typePROSITE-ProRule annotationAdd BLAST29

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 4R

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004064331 – 686Transcription activator of gluconeogenesis acuKAdd BLAST686

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 Zn(2)-C6 fungal-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000162694.
OrthoDBiEOG092C2QST.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2QFG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAEPKEQDS PAPSAERTEA SQEISAAGAQ ADKPKTEANG DGTANGASAN
60 70 80 90 100
GQKPNPKDPS RPRRKKARRA CFACQRAHLT CGDERPCQRC IKRGLQDACH
110 120 130 140 150
DGVRKKAKYL HDAPDGALMP GIGGTFYNNP MRNSLPLSRN GANAVNATGQ
160 170 180 190 200
QSAGANFYPT PQSTTYVYQE NTINQGSFPS QSPVSPTFNL KATPTARTNS
210 220 230 240 250
LSSVNPQPPS TSVSGPPGQG QNPFAGPFFD PSDPALFNFD LSSMNFENRY
260 270 280 290 300
GALEFGMLGH MATGAGDSPS DSATQRGSMG RSGSAQYAST PITGAPGFGE
310 320 330 340 350
SPGNQQPFMF GDPLLNEWPS GQAPGQPHLP GVYPQSGQGS AIPGHLSKAD
360 370 380 390 400
APHAFAIESG PASFNSPGAT TSPQMTTGLE ETPFHSAVAS KSNGLAPHGQ
410 420 430 440 450
RPMITTPSLK HQNLQVGVRR RQRNPSAIYD SVKEPYAYTS RFHGLTAFIQ
460 470 480 490 500
RRFPPQKTLQ IAKALASIRP SFIATTKTLN RDDLIFMEKC FQRTLWEYED
510 520 530 540 550
FINACGTPTI VCRRTGEIAA VGKEFSILTG WKKDVLLGKE PNLNVNTGGS
560 570 580 590 600
SMPNSGASSR SFTPRSTVDN TPGRPQPVFL AELLDDDSVV QFYEDFARLA
610 620 630 640 650
FGDSRGSVMT TCKLLKYKTK EDMEGAAAED SQRWNNHLRK GGIASEAGMN
660 670 680
QLGFKDGKVE CAYCWTVKRD VFDIPMLIVM NFLPCI
Length:686
Mass (Da):73,793
Last modified:March 6, 2007 - v1
Checksum:iBD6E9362737D5F81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270040 Genomic DNA. Translation: CAK48879.1.
RefSeqiXP_001400579.1. XM_001400542.2.

Genome annotation databases

EnsemblFungiiCAK48879; CAK48879; An02g14490.
GeneIDi4979989.
KEGGiang:ANI_1_1998024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270040 Genomic DNA. Translation: CAK48879.1.
RefSeqiXP_001400579.1. XM_001400542.2.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAK48879; CAK48879; An02g14490.
GeneIDi4979989.
KEGGiang:ANI_1_1998024.

Phylogenomic databases

HOGENOMiHOG000162694.
OrthoDBiEOG092C2QST.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiACUK_ASPNC
AccessioniPrimary (citable) accession number: A2QFG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: March 6, 2007
Last modified: November 30, 2016
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.