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A2QFG8

- ACUK_ASPNC

UniProt

A2QFG8 - ACUK_ASPNC

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Protein
Transcription activator of gluconeogenesis acuK
Gene
acuK, AN7468
Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes By similarity.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi71 – 9929Zn(2)-C6 fungal-type
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: InterPro
  3. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis acuK
Gene namesi
Name:acuK
ORF Names:AN7468
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000006706: Chromosome 4R

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 686686Transcription activator of gluconeogenesis acuK
PRO_0000406433Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00002901.

Family & Domainsi

Sequence similaritiesi

Belongs to the ERT1/acuK family.

Phylogenomic databases

eggNOGiNOG39365.
HOGENOMiHOG000162694.
OrthoDBiEOG70KGZB.

Family and domain databases

Gene3Di4.10.240.10. 1 hit.
InterProiIPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
[Graphical view]
SUPFAMiSSF57701. SSF57701. 1 hit.
PROSITEiPS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2QFG8-1 [UniParc]FASTAAdd to Basket

« Hide

MNAEPKEQDS PAPSAERTEA SQEISAAGAQ ADKPKTEANG DGTANGASAN    50
GQKPNPKDPS RPRRKKARRA CFACQRAHLT CGDERPCQRC IKRGLQDACH 100
DGVRKKAKYL HDAPDGALMP GIGGTFYNNP MRNSLPLSRN GANAVNATGQ 150
QSAGANFYPT PQSTTYVYQE NTINQGSFPS QSPVSPTFNL KATPTARTNS 200
LSSVNPQPPS TSVSGPPGQG QNPFAGPFFD PSDPALFNFD LSSMNFENRY 250
GALEFGMLGH MATGAGDSPS DSATQRGSMG RSGSAQYAST PITGAPGFGE 300
SPGNQQPFMF GDPLLNEWPS GQAPGQPHLP GVYPQSGQGS AIPGHLSKAD 350
APHAFAIESG PASFNSPGAT TSPQMTTGLE ETPFHSAVAS KSNGLAPHGQ 400
RPMITTPSLK HQNLQVGVRR RQRNPSAIYD SVKEPYAYTS RFHGLTAFIQ 450
RRFPPQKTLQ IAKALASIRP SFIATTKTLN RDDLIFMEKC FQRTLWEYED 500
FINACGTPTI VCRRTGEIAA VGKEFSILTG WKKDVLLGKE PNLNVNTGGS 550
SMPNSGASSR SFTPRSTVDN TPGRPQPVFL AELLDDDSVV QFYEDFARLA 600
FGDSRGSVMT TCKLLKYKTK EDMEGAAAED SQRWNNHLRK GGIASEAGMN 650
QLGFKDGKVE CAYCWTVKRD VFDIPMLIVM NFLPCI 686
Length:686
Mass (Da):73,793
Last modified:March 6, 2007 - v1
Checksum:iBD6E9362737D5F81
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270040 Genomic DNA. Translation: CAK48879.1.
RefSeqiXP_001400579.1. XM_001400542.2.

Genome annotation databases

EnsemblFungiiCADANGAT00002975; CADANGAP00002901; CADANGAG00002975.
GeneIDi4979989.
KEGGiang:ANI_1_1998024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AM270040 Genomic DNA. Translation: CAK48879.1 .
RefSeqi XP_001400579.1. XM_001400542.2.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 5061.CADANGAP00002901.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANGAT00002975 ; CADANGAP00002901 ; CADANGAG00002975 .
GeneIDi 4979989.
KEGGi ang:ANI_1_1998024.

Phylogenomic databases

eggNOGi NOG39365.
HOGENOMi HOG000162694.
OrthoDBi EOG70KGZB.

Family and domain databases

Gene3Di 4.10.240.10. 1 hit.
InterProi IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view ]
SMARTi SM00066. GAL4. 1 hit.
[Graphical view ]
SUPFAMi SSF57701. SSF57701. 1 hit.
PROSITEi PS50048. ZN2_CY6_FUNGAL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
    Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
    , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
    Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CBS 513.88 / FGSC A1513.

Entry informationi

Entry nameiACUK_ASPNC
AccessioniPrimary (citable) accession number: A2QFG8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: March 6, 2007
Last modified: April 16, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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