Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

An02g07600

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (An02g12770), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (An02g07600)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotationImported
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
ORF Names:An02g07600Imported
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)Imported
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 4R

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiA2QDM2

Interactioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00002213

Structurei

3D structure databases

ProteinModelPortaliA2QDM2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 458FAD_binding_2InterPro annotationAdd BLAST405
Domaini519 – 656Succ_DH_flav_CInterPro annotationAdd BLAST138

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

HOGENOMiHOG000160475
KOiK00234
OrthoDBiEOG092C1BHI

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

A2QDM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYRLSRAFHQ RTPLPNPFQT RPFLKRHRPF STLPRHSSPG PSVSEAPLFD
60 70 80 90 100
HYYDAIVIGA GGAGLRAAVG LTESGFRTAC ITKLFPTRSH TVAAQGGINA
110 120 130 140 150
ALGNMTKDDY RWHMYDTVKG SDWLGDQDAI HYMTREAPKA IYELENYGMA
160 170 180 190 200
FSRTEDGRIY QRALGGQSLD YGKGGQAYRT ACAADRTGHA MLHALYGEAL
210 220 230 240 250
KHDTQFFVEF FALDLLMVDG ACVGVICLSL EDGTLHRFFA RNTVLATGGY
260 270 280 290 300
GRAYFSCTSA HTSTGDGNAI VARAGLPNQD MEFVQFHPSG IHGAGVLITE
310 320 330 340 350
GARGEGGYLL NAHGERFMER YAPTAKDLAS RDVVARAMNL EIREGRGCGP
360 370 380 390 400
DKDHIHLQLS HLPAELIRSR LPGILETASI FAGIDITRDP IPVVPTVHYC
410 420 430 440 450
MGGIPTNYKG QVLTSSSHTS SGTNIPDAEV EPVPGLYAAG ECASVSVHGA
460 470 480 490 500
NRLGANSLLD IVVFGRACAL HIAETNEPNM PLHNIPHDDT PPSSLGQDSL
510 520 530 540 550
SSLSTTLHAT GDLPSSSLRH NLQRAMQTDL AVFRTHESLT TGLSKVIQVQ
560 570 580 590 600
NDFSTRLRTS DRSLIWNSDL VETLELRNLL TCAAQTAMAA LCRTESRGSH
610 620 630 640 650
AREDFPERDD EGWLKHSWTW QKDEKEEGVR VGYRGVIMKT LDEGDCKSVP

PVKRSY
Length:656
Mass (Da):71,710
Last modified:March 6, 2007 - v1
Checksum:iB46DDE574F80E218
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270018 Genomic DNA Translation: CAK37723.1
RefSeqiXP_001399893.1, XM_001399856.1

Genome annotation databases

EnsemblFungiiCAK37723; CAK37723; An02g07600
GeneIDi4979249
KEGGiang:ANI_1_2706024

Similar proteinsi

Entry informationi

Entry nameiA2QDM2_ASPNC
AccessioniPrimary (citable) accession number: A2QDM2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: March 28, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health