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A2QCU8 (SCONB_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene names
Name:sconB
ORF Names:An02g04800
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length670 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor By similarity.

Pathway

Protein modification; protein ubiquitination.

Subunit structure

Component of the SCF(sconB) E3 ubiquitin ligase complex By similarity.

Sequence similarities

Belongs to the WD repeat MET30/SCONB/SCON-2 family.

Contains 1 F-box domain.

Contains 7 WD repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 670670Probable E3 ubiquitin ligase complex SCF subunit sconB
PRO_0000397249

Regions

Domain163 – 20947F-box
Repeat339 – 37638WD 1
Repeat379 – 41840WD 2
Repeat420 – 45637WD 3
Repeat458 – 49942WD 4
Repeat553 – 59644WD 5
Repeat599 – 63638WD 6
Repeat639 – 67032WD 7

Sequences

Sequence LengthMass (Da)Tools
A2QCU8 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 2C50BE2AE02D9BCC

FASTA67074,900
        10         20         30         40         50         60 
MSSPPPFTSI FGGPAESAEE IDADADNSQL KPHNRSNVTA TSAKLVGKSV APFLAKHVPD 

        70         80         90        100        110        120 
QYAPLGSQNR EPAALSSANS RYCYRHRPDR KCRRQADEPT MDKLQRELES LPQSDQQGIA 

       130        140        150        160        170        180 
HVWSLFSAAP AKHRKLILQG IMAQCCFPQL SFISTTVRDL IRIDFIAALP PEISFKILCY 

       190        200        210        220        230        240 
LDTTSLCKAA QVSRRWRALA DDDVVWHRMC EQHIHRKCKK CGWGLPLLDR KRLRESKREI 

       250        260        270        280        290        300 
EIRATTWDVN GTSPKATPAL PEDASPVADS SGTGKRKPEP SEEETAVVKR HCQSLAMRPE 

       310        320        330        340        350        360 
GSEDYFKTRY RPWKEVYKDR FKVGTNWKYG RCSIRIFKGH TNGVMCLQFE DNILATGSYD 

       370        380        390        400        410        420 
ATIKIWDTDT GQEIRTLRGH ESGIRCLQFD DTKLISGSMD GSVKVWNWRT GDCISTYTGH 

       430        440        450        460        470        480 
RGGVIGLHFD ATILASASVD KTVKIWNFED KSTCLLRGHT DWVNAVRVDT ASRTVFSASD 

       490        500        510        520        530        540 
DCTVRLWDLD TKSCIRTFHG HVGQVQQVVP LPREFEFEEH DVECENDNLS TVSGDTEPAS 

       550        560        570        580        590        600 
LQATLGLESN AVISQSSPFG PSFESGRTAP PRYIVTSALD STIRLWETST GRCLRTFFGH 

       610        620        630        640        650        660 
LEGVWALAAD TLRIVSGAED RMIKIWDPRT GKCERTFTGH SGPVTCIGLG DSRFATGSED 

       670 
CEVRMYSFQS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM270009 Genomic DNA. Translation: CAK47657.1.

3D structure databases

ProteinModelPortalA2QCU8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5061.CADANGAP00001938.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00001996; CADANGAP00001938; CADANGAG00001996.

Phylogenomic databases

eggNOGCOG2319.
HOGENOMHOG000166480.
OrthoDBEOG7C5MHX.

Enzyme and pathway databases

UniPathwayUPA00143.

Family and domain databases

Gene3D2.130.10.10. 2 hits.
InterProIPR001810. F-box_dom.
IPR020472. G-protein_beta_WD-40_rep.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamPF00400. WD40. 7 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
SUPFAMSSF50978. SSF50978. 2 hits.
SSF81383. SSF81383. 2 hits.
PROSITEPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 4 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSCONB_ASPNC
AccessionPrimary (citable) accession number: A2QCU8
Entry history
Integrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: March 6, 2007
Last modified: February 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways