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A2QCU8

- SCONB_ASPNC

UniProt

A2QCU8 - SCONB_ASPNC

Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (06 Mar 2007)
      Previous versions | rss
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    Functioni

    Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

    Pathwayi

    GO - Biological processi

    1. protein ubiquitination Source: UniProtKB-UniPathway
    2. regulation of transcription, DNA-templated Source: UniProtKB-KW
    3. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation, Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable E3 ubiquitin ligase complex SCF subunit sconB
    Alternative name(s):
    Sulfur controller B
    Sulfur metabolite repression control protein B
    Gene namesi
    Name:sconB
    ORF Names:An02g04800
    OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
    Taxonomic identifieri425011 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000006706: Chromosome 4R

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 670670Probable E3 ubiquitin ligase complex SCF subunit sconBPRO_0000397249Add
    BLAST

    Interactioni

    Subunit structurei

    Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

    Protein-protein interaction databases

    STRINGi5061.CADANGAP00001938.

    Structurei

    3D structure databases

    ProteinModelPortaliA2QCU8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini163 – 20947F-boxPROSITE-ProRule annotationAdd
    BLAST
    Repeati339 – 37638WD 1Add
    BLAST
    Repeati379 – 41840WD 2Add
    BLAST
    Repeati420 – 45637WD 3Add
    BLAST
    Repeati458 – 49942WD 4Add
    BLAST
    Repeati553 – 59644WD 5Add
    BLAST
    Repeati599 – 63638WD 6Add
    BLAST
    Repeati639 – 67032WD 7Add
    BLAST

    Sequence similaritiesi

    Contains 1 F-box domain.PROSITE-ProRule annotation
    Contains 7 WD repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, WD repeat

    Phylogenomic databases

    eggNOGiCOG2319.
    HOGENOMiHOG000166480.
    OrthoDBiEOG7C5MHX.

    Family and domain databases

    Gene3Di2.130.10.10. 2 hits.
    InterProiIPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view]
    PRINTSiPR00320. GPROTEINBRPT.
    SMARTiSM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEiPS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2QCU8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSPPPFTSI FGGPAESAEE IDADADNSQL KPHNRSNVTA TSAKLVGKSV    50
    APFLAKHVPD QYAPLGSQNR EPAALSSANS RYCYRHRPDR KCRRQADEPT 100
    MDKLQRELES LPQSDQQGIA HVWSLFSAAP AKHRKLILQG IMAQCCFPQL 150
    SFISTTVRDL IRIDFIAALP PEISFKILCY LDTTSLCKAA QVSRRWRALA 200
    DDDVVWHRMC EQHIHRKCKK CGWGLPLLDR KRLRESKREI EIRATTWDVN 250
    GTSPKATPAL PEDASPVADS SGTGKRKPEP SEEETAVVKR HCQSLAMRPE 300
    GSEDYFKTRY RPWKEVYKDR FKVGTNWKYG RCSIRIFKGH TNGVMCLQFE 350
    DNILATGSYD ATIKIWDTDT GQEIRTLRGH ESGIRCLQFD DTKLISGSMD 400
    GSVKVWNWRT GDCISTYTGH RGGVIGLHFD ATILASASVD KTVKIWNFED 450
    KSTCLLRGHT DWVNAVRVDT ASRTVFSASD DCTVRLWDLD TKSCIRTFHG 500
    HVGQVQQVVP LPREFEFEEH DVECENDNLS TVSGDTEPAS LQATLGLESN 550
    AVISQSSPFG PSFESGRTAP PRYIVTSALD STIRLWETST GRCLRTFFGH 600
    LEGVWALAAD TLRIVSGAED RMIKIWDPRT GKCERTFTGH SGPVTCIGLG 650
    DSRFATGSED CEVRMYSFQS 670
    Length:670
    Mass (Da):74,900
    Last modified:March 6, 2007 - v1
    Checksum:i2C50BE2AE02D9BCC
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270009 Genomic DNA. Translation: CAK47657.1.

    Genome annotation databases

    EnsemblFungiiCADANGAT00001996; CADANGAP00001938; CADANGAG00001996.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AM270009 Genomic DNA. Translation: CAK47657.1 .

    3D structure databases

    ProteinModelPortali A2QCU8.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5061.CADANGAP00001938.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADANGAT00001996 ; CADANGAP00001938 ; CADANGAG00001996 .

    Phylogenomic databases

    eggNOGi COG2319.
    HOGENOMi HOG000166480.
    OrthoDBi EOG7C5MHX.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Family and domain databases

    Gene3Di 2.130.10.10. 2 hits.
    InterProi IPR001810. F-box_dom.
    IPR020472. G-protein_beta_WD-40_rep.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR019775. WD40_repeat_CS.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF12937. F-box-like. 1 hit.
    PF00400. WD40. 7 hits.
    [Graphical view ]
    PRINTSi PR00320. GPROTEINBRPT.
    SMARTi SM00256. FBOX. 1 hit.
    SM00320. WD40. 7 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 2 hits.
    SSF81383. SSF81383. 2 hits.
    PROSITEi PS50181. FBOX. 1 hit.
    PS00678. WD_REPEATS_1. 4 hits.
    PS50082. WD_REPEATS_2. 7 hits.
    PS50294. WD_REPEATS_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88."
      Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X., Contreras R., Cornell M.
      , Coutinho P.M., Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W., van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.
      Nat. Biotechnol. 25:221-231(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CBS 513.88 / FGSC A1513.

    Entry informationi

    Entry nameiSCONB_ASPNC
    AccessioniPrimary (citable) accession number: A2QCU8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 10, 2010
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3