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Protein

Probable E3 ubiquitin ligase complex SCF subunit sconB

Gene

sconB

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.By similarity

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Probable E3 ubiquitin ligase complex SCF subunit sconB
Alternative name(s):
Sulfur controller B
Sulfur metabolite repression control protein B
Gene namesi
Name:sconB
ORF Names:An02g04800
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 4R

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003972491 – 670Probable E3 ubiquitin ligase complex SCF subunit sconBAdd BLAST670

Proteomic databases

PaxDbiA2QCU8

Interactioni

Subunit structurei

Component of the SCF(sconB) E3 ubiquitin ligase complex.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi5061.CADANGAP00001938

Structurei

3D structure databases

ProteinModelPortaliA2QCU8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini163 – 209F-boxPROSITE-ProRule annotationAdd BLAST47
Repeati339 – 376WD 1Add BLAST38
Repeati379 – 418WD 2Add BLAST40
Repeati420 – 456WD 3Add BLAST37
Repeati458 – 499WD 4Add BLAST42
Repeati553 – 596WD 5Add BLAST44
Repeati599 – 636WD 6Add BLAST38
Repeati639 – 670WD 7Add BLAST32

Sequence similaritiesi

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

HOGENOMiHOG000166480
OrthoDBiEOG092C10HM

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF12937 F-box-like, 1 hit
PF00400 WD40, 6 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 2 hits
SSF81383 SSF81383, 2 hits
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit
PS00678 WD_REPEATS_1, 4 hits
PS50082 WD_REPEATS_2, 7 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

A2QCU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPPPFTSI FGGPAESAEE IDADADNSQL KPHNRSNVTA TSAKLVGKSV
60 70 80 90 100
APFLAKHVPD QYAPLGSQNR EPAALSSANS RYCYRHRPDR KCRRQADEPT
110 120 130 140 150
MDKLQRELES LPQSDQQGIA HVWSLFSAAP AKHRKLILQG IMAQCCFPQL
160 170 180 190 200
SFISTTVRDL IRIDFIAALP PEISFKILCY LDTTSLCKAA QVSRRWRALA
210 220 230 240 250
DDDVVWHRMC EQHIHRKCKK CGWGLPLLDR KRLRESKREI EIRATTWDVN
260 270 280 290 300
GTSPKATPAL PEDASPVADS SGTGKRKPEP SEEETAVVKR HCQSLAMRPE
310 320 330 340 350
GSEDYFKTRY RPWKEVYKDR FKVGTNWKYG RCSIRIFKGH TNGVMCLQFE
360 370 380 390 400
DNILATGSYD ATIKIWDTDT GQEIRTLRGH ESGIRCLQFD DTKLISGSMD
410 420 430 440 450
GSVKVWNWRT GDCISTYTGH RGGVIGLHFD ATILASASVD KTVKIWNFED
460 470 480 490 500
KSTCLLRGHT DWVNAVRVDT ASRTVFSASD DCTVRLWDLD TKSCIRTFHG
510 520 530 540 550
HVGQVQQVVP LPREFEFEEH DVECENDNLS TVSGDTEPAS LQATLGLESN
560 570 580 590 600
AVISQSSPFG PSFESGRTAP PRYIVTSALD STIRLWETST GRCLRTFFGH
610 620 630 640 650
LEGVWALAAD TLRIVSGAED RMIKIWDPRT GKCERTFTGH SGPVTCIGLG
660 670
DSRFATGSED CEVRMYSFQS
Length:670
Mass (Da):74,900
Last modified:March 6, 2007 - v1
Checksum:i2C50BE2AE02D9BCC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM270009 Genomic DNA Translation: CAK47657.1

Genome annotation databases

EnsemblFungiiCAK47657; CAK47657; An02g04800

Similar proteinsi

Entry informationi

Entry nameiSCONB_ASPNC
AccessioniPrimary (citable) accession number: A2QCU8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 10, 2010
Last sequence update: March 6, 2007
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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