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A2QBQ3 (EGLX_ASPNC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable endo-1,3(4)-beta-glucanase An02g00850

EC=3.2.1.6
Alternative name(s):
Mixed-linked glucanase An02g00850
Gene names
ORF Names:An02g00850
OrganismAspergillus niger (strain CBS 513.88 / FGSC A1513) [Complete proteome]
Taxonomic identifier425011 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length739 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Mixed-linked glucanase involved in the degradation of complex natural cellulosic substrates By similarity.

Catalytic activity

Endohydrolysis of (1->3)- or (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolyzed is itself substituted at C-3.

Subcellular location

Cell membrane; Lipid-anchorGPI-anchor By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 717693Probable endo-1,3(4)-beta-glucanase An02g00850
PRO_5000219530
Propeptide718 – 73922Removed in mature form Potential
PRO_0000395090

Regions

Compositional bias287 – 2926Poly-Ser
Compositional bias325 – 686362Ala-rich
Compositional bias419 – 706288Ser-rich

Sites

Active site1401Nucleophile By similarity
Active site1451Proton donor By similarity

Amino acid modifications

Lipidation7171GPI-anchor amidated glycine Potential
Glycosylation591N-linked (GlcNAc...) Potential
Glycosylation741N-linked (GlcNAc...) Potential
Glycosylation3961N-linked (GlcNAc...) Potential
Glycosylation4591N-linked (GlcNAc...) Potential
Glycosylation4821N-linked (GlcNAc...) Potential
Glycosylation5261N-linked (GlcNAc...) Potential
Glycosylation5371N-linked (GlcNAc...) Potential
Glycosylation5691N-linked (GlcNAc...) Potential
Glycosylation5811N-linked (GlcNAc...) Potential
Glycosylation5921N-linked (GlcNAc...) Potential
Glycosylation6201N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A2QBQ3 [UniParc].

Last modified March 6, 2007. Version 1.
Checksum: 7640750996F31B92

FASTA73972,556
        10         20         30         40         50         60 
MPTSTLLWSV GSLALSSMVL PAAASSYELV ETWKGEDFLT AFDFYTGADP TNGFVTYANQ 

        70         80         90        100        110        120 
SYAESTGLVK VNSNGTFYMG VDHTTKLSTN GPGRESVRIG SNKYYDEGLF IIDLQHMPGS 

       130        140        150        160        170        180 
VCGTWPAFWS TGKNWPTDGE IDIIEGVNKN EANEIVLHTS GTCQVSSQKM SGTLTSTECG 

       190        200        210        220        230        240 
EDAGTTGCVV EGTQGSSGTP FNENGGGVYA MQWTDEFLKF WFFPRGSIPS SITKGDPDVA 

       250        260        270        280        290        300 
AFGTPMAHME GSCSIAEHFK AQQFIFDTTF CGDWAGGVYS TSGCPVSDSS SSFKSCVAYV 

       310        320        330        340        350        360 
AENPTAFAES YWEINYIKIY QTGVAASASA SASHVESAAS VAETISAVRE GTNSVVATTT 

       370        380        390        400        410        420 
AATIAVTSTA DAETATTMAG ATTVAASTET SAADENGSSA STSTHYVTMT TTICPIAESS 

       430        440        450        460        470        480 
SAAAALAGGS SEATEASNSE GSPAAATPSS VTGASAEANE SESTSAAVTT PSTSTGASAE 

       490        500        510        520        530        540 
ANGSESSSAS EAGSVAGATP SSVSTTGASG EADSSEGASA AATPSNVSST GASAEANGSE 

       550        560        570        580        590        600 
DSSASSEAKT VAPSIPSSVT GASAEANGND SASSNAATAS NVSGASAQAG DNESTPASAG 

       610        620        630        640        650        660 
ANAGSSAAPS SVSGASAEAN GSEGSSSHSS GSQAGAHSYG SVPSSAAAYG RPAPSSSSHA 

       670        680        690        700        710        720 
FATAPSSTGS SRVPTSAAAA NNAAAATQGS SASGSNSGSS GHGSSSATTP STPVFTGGAN 

       730 
KLTLGASSVL SVLAFALLA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AM269996 Genomic DNA. Translation: CAK96300.1.
RefSeqXP_001399223.1. XM_001399186.1.

3D structure databases

ProteinModelPortalA2QBQ3.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH16. Glycoside Hydrolase Family 16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADANGAT00001593; CADANGAP00001543; CADANGAG00001593.
GeneID4978566.
KEGGang:ANI_1_2196024.

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000166269.
OrthoDBEOG7HB5KN.

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
[Graphical view]
SUPFAMSSF49899. SSF49899. 2 hits.
ProtoNetSearch...

Entry information

Entry nameEGLX_ASPNC
AccessionPrimary (citable) accession number: A2QBQ3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: March 6, 2007
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries