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Protein

Probable alpha-L-arabinofuranosidase A

Gene

abfA

Organism
Aspergillus niger (strain CBS 513.88 / FGSC A1513)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Alpha-L-arabinofuranosidase involved in the degradation of arabinoxylan, a major component of plant hemicellulose. Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.

Pathwayi: L-arabinan degradation

This protein is involved in the pathway L-arabinan degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway L-arabinan degradation and in Glycan metabolism.

GO - Molecular functioni

GO - Biological processi

  • arabinan catabolic process Source: UniProtKB-UniPathway
  • arabinose metabolic process Source: UniProtKB
  • hemicellulose catabolic process Source: ASPGD
  • L-arabinose metabolic process Source: ASPGD
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00667.

Protein family/group databases

CAZyiGH51. Glycoside Hydrolase Family 51.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable alpha-L-arabinofuranosidase A (EC:3.2.1.55)
Short name:
ABF A
Short name:
Arabinosidase A
Gene namesi
Name:abfA
ORF Names:An01g00330
OrganismiAspergillus niger (strain CBS 513.88 / FGSC A1513)
Taxonomic identifieri425011 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000006706 Componenti: Chromosome 2R

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500021928726 – 628Probable alpha-L-arabinofuranosidase AAdd BLAST603

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi36N-linked (GlcNAc...)Sequence analysis1
Glycosylationi51N-linked (GlcNAc...)Sequence analysis1
Glycosylationi74N-linked (GlcNAc...)Sequence analysis1
Glycosylationi152N-linked (GlcNAc...)Sequence analysis1
Glycosylationi171N-linked (GlcNAc...)Sequence analysis1
Glycosylationi260N-linked (GlcNAc...)Sequence analysis1
Glycosylationi359N-linked (GlcNAc...)Sequence analysis1
Glycosylationi440N-linked (GlcNAc...)Sequence analysis1
Glycosylationi493N-linked (GlcNAc...)Sequence analysis1
Glycosylationi610N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliA2Q7E0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 51 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000115340.
KOiK01209.
OrthoDBiEOG092C0YIX.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR010720. Alpha-L-AF_C.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF06964. Alpha-L-AF_C. 1 hit.
[Graphical view]
SMARTiSM00813. Alpha-L-AF_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

A2Q7E0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAFSALSGV SAVSLLLSLV QNAHGISLKV STQGGNSSSP ILYGFMFEDI
60 70 80 90 100
NHSGDGGIYG QMLQNPGLQG TAPNLTAWAA VGDATIAIDG DSPLTSAIPS
110 120 130 140 150
TIKLNIADDA TGAVGLTNEG YWGIPVDGSE FHSSFWIKGD YSGDITVRLV
160 170 180 190 200
GNYTGTEYGS TTITHTSTAD NFTQASVKFP TTKAPDGNVL YELTVDGSVA
210 220 230 240 250
AGSSLNFGYL TLFGETYKSR ENGLKPQLAN VLDDMKGSFL RFPGGNNLEG
260 270 280 290 300
NSAENRWKWN ETIGDLWDRP GREGTWTYYN TDGLGLHEYF YWCEDLGLVP
310 320 330 340 350
VLGVWDGFAL ESGGNTPLTG DALTPYIDDV LNELEYILGD TSTTYGAWRA
360 370 380 390 400
ANGQEEPWNL TMVEIGNEDM LGGGCESYAE RFTAFYDAIH AAYPDLILIA
410 420 430 440 450
STSEADCLPE SMPEGSWVDY HDYSTPDGLV GQFNYFDNLN RSVPYFIGEY
460 470 480 490 500
SRWEIDWPNM KGSVAEAVFM IGFERNSDVV KMAAYAPLLQ LINSTQWTPD
510 520 530 540 550
LIGYTQSPGD IFLSTSYYVQ EMFSRNRGDT IKEVTSDSDF GPLYWVASSA
560 570 580 590 600
GDSYYMKLAN YGSETQDLTV SIPGTSTGKL TVLADSDPDA YNSDTQTLVT
610 620
PSESTVQASN GTFTFSLPAW AVAVLAAN
Length:628
Mass (Da):67,948
Last modified:March 6, 2007 - v1
Checksum:iD2961CCBB4195041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM269950 Genomic DNA. Translation: CAK43424.1.
RefSeqiXP_001388482.1. XM_001388445.1.

Genome annotation databases

EnsemblFungiiCAK43424; CAK43424; An01g00330.
GeneIDi4978177.
KEGGiang:ANI_1_42014.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM269950 Genomic DNA. Translation: CAK43424.1.
RefSeqiXP_001388482.1. XM_001388445.1.

3D structure databases

ProteinModelPortaliA2Q7E0.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH51. Glycoside Hydrolase Family 51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAK43424; CAK43424; An01g00330.
GeneIDi4978177.
KEGGiang:ANI_1_42014.

Phylogenomic databases

HOGENOMiHOG000115340.
KOiK01209.
OrthoDBiEOG092C0YIX.

Enzyme and pathway databases

UniPathwayiUPA00667.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR010720. Alpha-L-AF_C.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF06964. Alpha-L-AF_C. 1 hit.
[Graphical view]
SMARTiSM00813. Alpha-L-AF_C. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiABFA_ASPNC
AccessioniPrimary (citable) accession number: A2Q7E0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: March 6, 2007
Last modified: November 30, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.