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Protein

Pectinesterase

Gene

11442886

Organism
Medicago truncatula (Barrel medic) (Medicago tribuloides)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Pectin + n H2O = n methanol + pectate.UniRule annotationSAAS annotation

Pathwayi: pectin degradation

This protein is involved in step 1 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.UniRule annotationSAAS annotation
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase (11412480), Pectinesterase (25481268), Pectinesterase (11407498), Pectinesterase (11440079), Pectinesterase (11407580), Pectinesterase (11413602), Pectinesterase/pectinesterase inhibitor (11442613), Pectinesterase (11406457), Pectinesterase (11405622), Pectinesterase (25482588), Pectinesterase (11439645), Pectinesterase (25488084), Pectinesterase (11417508), Pectinesterase (25498185), Pectinesterase (11442886), Pectinesterase, Pectinesterase (PEF1), Pectinesterase (PEF2), Pectinesterase (25487202), Pectinesterase (25494081), Pectinesterase (PE5), Pectinesterase (PE6), Pectinesterase (PE7), Pectinesterase (PE8), Pectinesterase (PE9), Pectinesterase (11439145), Pectinesterase (25499611), Pectinesterase (11423282), Pectinesterase (25501131), Pectinesterase (11423283), Pectinesterase (11431826), Pectinesterase (11426630), Pectinesterase (11430029), Pectinesterase (MtrDRAFT_AC144563g28v2), Pectinesterase, Pectinesterase (25483614), Pectinesterase (11418679), Pectinesterase (11421037), Pectinesterase (11410524), Pectinesterase (11418401), Pectinesterase (MtrDRAFT_AC144563g9v2), Pectinesterase (25499549), Pectinesterase (11426492), Pectinesterase (11444976), Pectinesterase (11417090), Pectinesterase (25481100), Pectinesterase (11444095), Pectinesterase (11442846), Pectinesterase (25499608), Pectinesterase (11426492), Pectinesterase (11445516), Pectinesterase (25502277), Pectinesterase (11441702), Pectinesterase (11438432), Pectinesterase (11425912), Pectinesterase (11435293), Pectinesterase (25502276), Pectinesterase (11435310), Pectinesterase (MtrDRAFT_AC144563g27v2), Pectinesterase (11414917), Pectinesterase (11441689), Pectinesterase (11432815), Pectinesterase, Pectinesterase (11413863), Pectinesterase (11445925), Pectinesterase (11437334), Pectinesterase (25484751), Pectinesterase (25499610), Pectinesterase (25495763), Pectinesterase (25496985), Pectinesterase (25501130), Pectinesterase (11417435), Pectinesterase (11422393), Pectinesterase (25479539), Pectinesterase/pectinesterase inhibitor (11434522), Pectinesterase (25488119), Pectinesterase (11437869), Pectinesterase/pectinesterase inhibitor (11433107), Pectinesterase (25491636), Pectinesterase (25491632), Pectinesterase (11424461), Pectinesterase (11431300), Pectinesterase (25491630), Pectinesterase, Pectinesterase (11415886), Pectinesterase (25491850), Pectinesterase (11445926), Pectinesterase (11441469), Pectinesterase (11445254), Pectinesterase (MtrDRAFT_AC148775g29v2), Pectinesterase (25488086), Pectinesterase (25499609), Pectinesterase, Pectinesterase (pef1), Pectinesterase (11442886), Pectinesterase, Pectinesterase (11421011), Pectinesterase (11407251), Pectinesterase/pectinesterase inhibitor (25481099), Pectinesterase (25488085), Pectinesterase (per), Pectinesterase (25492829), Pectinesterase (25494082), Pectinesterase (11419442), Pectinesterase; Pectinesterase inhibitor (MtrDRAFT_AC155891g3v1), Pectinesterase (11405415), Pectinesterase (11446388), Pectinesterase (MtrDRAFT_AC155891g10v1), Pectinesterase (11437296)
  2. Pectate lyase, Pectate lyase (25486209), Pectate lyase (11406962), Pectate lyase (11408829), Pectate lyase (11438708), Pectate lyase (11417669), Pectate lyase (11411484), Pectate lyase (11413286), Pectate lyase (25483947), Pectate lyase (25484083), Pectate lyase (11417956), Pectate lyase (11408285), Pectate lyase (25485548), Pectate lyase, Pectate lyase (11408313), Pectate lyase (11446795), Pectate lyase (11405853), Pectate lyase (11413513), Pectate lyase, Pectate lyase (25485739), Pectate lyase (11426383), Pectate lyase (11409358), Pectate lyase (11408643), Pectate lyase (11410645), Pectate lyase (11439569), Pectate lyase (25499338), Pectate lyase (25486210), Pectate lyase (11415726), Pectate lyase (11409719), Pectate lyase (11409720), Pectate lyase (25502784), Pectate lyase (11416043), Pectate lyase (11414429), Pectate lyase (11427725), Pectate lyase (25489517), Pectate lyase (25489517), Pectate lyase (25484270), Pectate lyase (25495277), Pectate lyase (25483116), Pectate lyase
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei373PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl esteraseUniRule annotationSAAS annotation, Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00545; UER00823.

Names & Taxonomyi

Protein namesi
Recommended name:
PectinesteraseUniRule annotation (EC:3.1.1.11UniRule annotation)
Gene namesi
Name:11442886Imported
Ordered Locus Names:MTR_2g044810Imported
ORF Names:MtrDRAFT_AC155891g18v1Imported
OrganismiMedicago truncatula (Barrel medic) (Medicago tribuloides)
Taxonomic identifieri3880 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeTrifolieaeMedicago
Proteomesi
  • UP000002051 Componenti: Chromosome 2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20UniRule annotationAdd BLAST20
ChainiPRO_501089492621 – 534PectinesteraseUniRule annotationAdd BLAST514

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 186PMEIInterPro annotationAdd BLAST151

Sequence similaritiesi

In the C-terminal section; belongs to the pectinesterase family.SAAS annotation
In the N-terminal section; belongs to the PMEI family.SAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

OMAiCNIVARM.
OrthoDBiEOG09360CYZ.

Family and domain databases

Gene3Di1.20.140.40. 1 hit.
2.160.20.10. 1 hit.
InterProiView protein in InterPro
IPR035513. Invertase/methylesterase_inhib.
IPR012334. Pectin_lyas_fold.
IPR011050. Pectin_lyase_fold/virulence.
IPR033131. Pectinesterase_Asp_AS.
IPR000070. Pectinesterase_cat.
IPR006501. Pectinesterase_inhib_dom.
PfamiView protein in Pfam
PF01095. Pectinesterase. 1 hit.
PF04043. PMEI. 1 hit.
SMARTiView protein in SMART
SM00856. PMEI. 1 hit.
SUPFAMiSSF101148. SSF101148. 1 hit.
SSF51126. SSF51126. 1 hit.
TIGRFAMsiTIGR01614. PME_inhib. 1 hit.
PROSITEiView protein in PROSITE
PS00503. PECTINESTERASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A2Q3Z8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASSSHKLFI LLFTILFSLT LPLNTNTSIT TSLNPNKLTS LKSLCKTTPY
60 70 80 90 100
PKLCFNSLKL SISININPNI ITYLLHSLQL AISETTKLSN LFHDVGTSNI
110 120 130 140 150
VEKQRGSIQD CKELHQSTLT SLKRSLSGIR SSNKRNIADA RIYLSAALTN
160 170 180 190 200
KNTCLDGLDS ASGTYKPILV DSIINTYKHV SNSLSMLSNH APEPSNQKGH
210 220 230 240 250
NKNLVSPKWL SKRLDFDEYD PNEMLVVSAD GSGNFSTIND AINFAPNNSL
260 270 280 290 300
VRIVIYVKEG YYDENVEIPS YKTNIVMLGD GSDSTVITGN RSVVDGWTTF
310 320 330 340 350
RSATLAVSGD GFLARDIAIE NRAGPEKHQA VALRVNADLT AFYKCAIYGY
360 370 380 390 400
QDTLYVHSFR QFYRECDIYG TIDFIFGNAA VVLQECDIVS RMPLPGQFTV
410 420 430 440 450
ITAQSRDNPD EDTGISIQNC SIIATDELYS NSSKVKSYLG RPWRVFSRTV
460 470 480 490 500
LIESYIDDFI DQKGWTKWSN DQGLDTLFYG EYENYGPGSK IDNRVEWVGY
510 520 530
HLMDYNDAYN FSVSEFIIGD QWLESTSVPY DDGI
Length:534
Mass (Da):59,660
Last modified:March 6, 2007 - v1
Checksum:i8F5AB83E205D4CB6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC155891 Genomic DNA. Translation: ABN08348.1.
CM001218 Genomic DNA. Translation: AES65632.1.
RefSeqiXP_003595381.1. XM_003595333.2.

Genome annotation databases

EnsemblPlantsiAES65632; AES65632; MTR_2g044810.
GeneIDi11442886.
GrameneiAES65632; AES65632; MTR_2g044810.
KEGGimtr:MTR_2g044810.

Similar proteinsi

Entry informationi

Entry nameiA2Q3Z8_MEDTR
AccessioniPrimary (citable) accession number: A2Q3Z8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 6, 2007
Last sequence update: March 6, 2007
Last modified: February 28, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported