A2NXD2 (A2NXD2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Immunolglobulin kappa light chain variable region L22 EMBL CAA51335.1

Gene names

Name:

IGLV EMBL CAA51335.1

Organism

Homo sapiens (Human) EMBL CAA51335.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	117 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL CAA51335.1
Gene Ontology (GO)
Biological_process	complement activation, classical pathway Traceable author statement. Source: Reactome innate immune response Traceable author statement. Source: Reactome
Cellular_component	extracellular region Traceable author statement. Source: Reactome plasma membrane Traceable author statement. Source: Reactome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	‹1 – 22	›22	Potential EMBL CAA51335.1
	Chain	23 – ›117	›95	Potential EMBL CAA51335.1		PRO_5000219025
Experimental info
	Non-terminal residue	1	1	EMBL CAA51335.1
	Non-terminal residue	117	1	EMBL CAA51335.1

Sequences

	Sequence		Length	Mass (Da)
	A2NXD2 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 1B6A9B68A1D171D2	FASTA	117	13,026
	10 20 30 40 50 60 MDMRVPAQLL GLLLLWLPGV RFDIQMIQSP SFLSASVGDR VSIICWASEG ISSNLAWYLQ 70 80 90 100 110 KPGKSPKLFL YDAKDLHPGV SSRFSGRGSG TDFTLTIISL KPEDFAAYYC KQDFSYP

References

[1]	"The V kappa genes of the L regions and the repertoire of V kappa gene sequences in the human germ line." Huber C., Schable K.F., Huber E., Klein R., Meindl A., Thiebe R., Lamm R., Zachau H.G. Eur. J. Immunol. 23:2868-2875(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Placenta St EMBL CAA51335.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X72816 Genomic DNA. Translation: CAA51335.1.
IPI	IPI00939941.
PIR	S41811.
3D structure databases
ProteinModelPortal	A2NXD2.
SMR	A2NXD2. Positions 23-117.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000374813. A2NXD2.
Proteomic databases
PaxDb	A2NXD2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000059537.
HOVERGEN	HBG018013.
OrthoDB	EOG4CG09R.
Enzyme and pathway databases
Reactome	REACT_160300. Binding and Uptake of Ligands by Scavenger Receptors. REACT_6900. Immune System.
Family and domain databases
Gene3D	2.60.40.10. 1 hit.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR013106. Ig_V-set. IPR003596. Ig_V-set_subgr. [Graphical view]
Pfam	PF07686. V-set. 1 hit. [Graphical view]
SMART	SM00406. IGv. 1 hit. [Graphical view]
PROSITE	PS50835. IG_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35461226.

Entry information

Entry name

A2NXD2_HUMAN

Accession

Primary (citable) accession number: A2NXD2

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.