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Protein
Submitted name:

Beta-chain

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Beta-chainImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 PotentialImportedAdd
BLAST
Chaini30 – ›144›115beta-chainImportedPRO_5000218754Add
BLAST

Proteomic databases

PRIDEiA2NTY6.

Expressioni

Gene expression databases

GenevestigatoriA2NTY6.

Interactioni

Protein-protein interaction databases

IntActiA2NTY6. 1 interaction.
STRINGi10090.ENSMUSP00000100086.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2E7LX-ray2.50C/D30-144[»]
2ICWX-ray2.41J/L30-144[»]
2OI9X-ray2.35C30-144[»]
2PXYX-ray2.23B32-144[»]
2Z31X-ray2.70B32-123[»]
2Z35X-ray2.20B32-144[»]
3E2HX-ray3.80C31-144[»]
ProteinModelPortaliA2NTY6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiA2NTY6.

Family & Domainsi

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiNOG123478.
HOVERGENiHBG099362.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Sequence processingi: The displayed sequence is further processed into a mature form.

A2NTY6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNTAFPDPA WNTTLLSWVA LFLLGTKHME AAVTQSPRNK VAVTGGKVTL
60 70 80 90 100
SCNQTNNHNN MYWYRQDTGH GLRLIHYSYG AGSTEKGDIP DGYKASRPSQ
110 120 130 140
ENFSLILELA TPSQTSVYFC ASGELGGFNQ DTQYFGPGTR LLVL
Length:144
Mass (Da):15,812
Last modified:February 20, 2007 - v1
Checksum:i4071AC8C0A490C60
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei144 – 1441Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02784 mRNA. Translation: CAA26555.1.

Genome annotation databases

UCSCiuc009boa.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X02784 mRNA. Translation: CAA26555.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2E7LX-ray2.50C/D30-144[»]
2ICWX-ray2.41J/L30-144[»]
2OI9X-ray2.35C30-144[»]
2PXYX-ray2.23B32-144[»]
2Z31X-ray2.70B32-123[»]
2Z35X-ray2.20B32-144[»]
3E2HX-ray3.80C31-144[»]
ProteinModelPortaliA2NTY6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiA2NTY6. 1 interaction.
STRINGi10090.ENSMUSP00000100086.

Proteomic databases

PRIDEiA2NTY6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc009boa.2. mouse.

Phylogenomic databases

eggNOGiNOG123478.
HOVERGENiHBG099362.

Miscellaneous databases

EvolutionaryTraceiA2NTY6.
NextBioi35544479.

Gene expression databases

GenevestigatoriA2NTY6.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013106. Ig_V-set.
IPR003596. Ig_V-set_subgr.
[Graphical view]
PfamiPF07686. V-set. 1 hit.
[Graphical view]
SMARTiSM00406. IGv. 1 hit.
[Graphical view]
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments."
    Barth R.K., Kim B.S., Lan N.C., Hunkapiller T., Sobieck N., Winoto A., Gershennffeld H., Okada C., Hansburg D., Weissman I.L., Hood L.
    Nature 316:517-523(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/KaImported.
  2. "How a single T cell receptor recognizes both self and foreign MHC."
    Colf L.A., Bankovich A.J., Hanick N.A., Bowerman N.A., Jones L.L., Kranz D.M., Garcia K.C.
    Cell 129:135-146(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 30-144, ACTIVE SITE.
  3. "Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'."
    Feng D., Bond C.J., Ely L.K., Maynard J., Garcia K.C.
    Nat. Immunol. 8:975-983(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 32-144, ACTIVE SITE.
  4. "Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC."
    Wang L., Zhao Y., Li Z., Guo Y., Jones L.L., Kranz D.M., Mourad W., Li H.
    Nat. Struct. Mol. Biol. 14:169-171(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) OF 30-144, ACTIVE SITE.
  5. "Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation."
    Jones L.L., Colf L.A., Stone J.D., Garcia K.C., Kranz D.M.
    J. Immunol. 181:6255-6264(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.80 ANGSTROMS) OF 31-144, ACTIVE SITE.

Entry informationi

Entry nameiA2NTY6_MOUSE
AccessioniPrimary (citable) accession number: A2NTY6
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: January 7, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.