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A2I7N3 (SPA37_BOVIN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Serpin A3-7
Gene names
Name:SERPINA3-7
OrganismBos taurus (Bovine) [Reference proteome]
Taxonomic identifier9913 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Cetartiodactyla › Ruminantia › Pecora › Bovidae › Bovinae › Bos

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Serine protease inhibitor By similarity. UniProtKB Q9TTE1

Subunit structure

Homodimer By similarity. UniProtKB Q9TTE1

Subcellular location

Cytoplasmic vesicle › secretory vesicle › chromaffin granule By similarity. Secreted By similarity UniProtKB Q9TTE1.

Sequence similarities

Belongs to the serpin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2525 By similarity
Chain26 – 417392Serpin A3-7
PRO_0000401161

Amino acid modifications

Glycosylation1031N-linked (GlcNAc...) Potential
Glycosylation1831N-linked (GlcNAc...) Potential
Glycosylation2211N-linked (GlcNAc...) Potential
Glycosylation2671N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
A2I7N3 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 06DD58B2CFC1AC8D

FASTA41746,942
        10         20         30         40         50         60 
MRTERTSFLL ALGLLVSGFC SRVHCLPENV TPEEQHKGTS VDGHSLASSN TDFALSLYKQ 

        70         80         90        100        110        120 
LALKDPNKNV IFSPLSISIA LAFLSLGAHD HTVTEILEGL KFNLTETPET EIHQGFQHLL 

       130        140        150        160        170        180 
QTFNQPSNQL QLSVGNAMFA SEELKLLDKF RKDAEAFYAS EVLSTNFKDS EAAVKLINEY 

       190        200        210        220        230        240 
VKNKTHGKIE KLFNDLDVLT NLILLNYIFF KAQWKTPFNP NHTYESEFHV SQNERVIVPM 

       250        260        270        280        290        300 
MTLYLETPYF RDEELGCTLV ELTYTSNDSA LFILPDEGKM QDLEAKLTPE TLTRWRSSLQ 

       310        320        330        340        350        360 
PRLIHRLRLP RFSISSHYQL KDILSQLGIK KIFTSDAGFS GITDDHKLAV SHVIHKAVLD 

       370        380        390        400        410 
VGEEGTEGAA VTAVVMATSS LLHTLTVSFN RPFLLSIFCK ETQSIIFWGK VTNPKEA

« Hide

References

[1]"An original SERPINA3 gene cluster: elucidation of genomic organization and gene expression in the Bos taurus 21q24 region."
Pelissier P., Delourme D., Germot A., Blanchet X., Becila S., Maftah A., Leveziel H., Ouali A., Bremaud L.
BMC Genomics 9:151-151(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], NOMENCLATURE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		EF153630 Genomic DNA. Translation: ABM55500.1.
IPIIPI00686980.
UniGeneBt.55387.
Bt.92049.

3D structure databases

ModBaseSearch...

Protein family/group databases

MEROPSI04.034.

Proteomic databases

PaxDbA2I7N3.
PRIDEA2I7N3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG4826.
HOGENOMHOG000238521.
HOVERGENHBG005957.

Family and domain databases

InterProIPR023795. Protease_inhib_I4_serpin_CS.
IPR023796. Serpin_dom.
IPR000215. Serpin_fam.
[Graphical view]
PANTHERPTHR11461. PTHR11461. 1 hit.
PfamPF00079. Serpin. 1 hit.
[Graphical view]
SMARTSM00093. SERPIN. 1 hit.
[Graphical view]
SUPFAMSSF56574. Prot_inh_serpin. 1 hit.
PROSITEPS00284. SERPIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPA37_BOVIN
AccessionPrimary (citable) accession number: A2I7N3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: February 20, 2007
Last modified: April 3, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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