A2EXA5 (A2EXA5_TRIVA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
SET domain containing protein EMBL EAY02704.1

Gene names

ORF Names:

TVAG_440830 EMBL EAY02704.1

Organism

Trichomonas vaginalis [Reference proteome]

Taxonomic identifier

5722 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Parabasalia › Trichomonadida › Trichomonadidae › Trichomonas

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone]. SAAS SAAS001214
Sequence similarities	Contains 1 SET domain. RuleBase RU004538 SAAS SAAS001214 Contains 1 post-SET domain. RuleBase RU004541

Ontologies

Keywords
Cellular component	Nucleus SAAS SAAS003616
Molecular function	Methyltransferase RuleBase RU004541 SAAS SAAS001214 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	nucleus Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2EXA5 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: DC0916EA13F4D7A9	FASTA	486	56,753
	10 20 30 40 50 60 MMMNKRIRPQ RRHSSSDSLD NPSSYDEDER KKSFSNRMTN REDKSEIKTP TRSDSPKVMN 70 80 90 100 110 120 HNNKEDKKEV IRSRSKNIQQ NSEMRVTREH IRHENADHPS QIEKRERFEN HRRPNRENKD 130 140 150 160 170 180 LRVKIDIGDR KTTSHDHQRE KKEKSSKIIP QNEKPKEPKI KFEKPSIPVP QITKKVKKET 190 200 210 220 230 240 DNINLPLPPP QIPPETEDIK PAVISRPKAQ LVTGKIPKCS RIVPIKCLSF KKRDKYYRAA 250 260 270 280 290 300 NANRKQLDII EETLKDEERQ NQKFYQLLSS FKGANSDLIS VELDTKDMKL NYIRFEKSKI 310 320 330 340 350 360 EGFGVKTTIP IRKGEKVIEY IGEVIRPIIA DKRQINYEKM GNHGTYVFKA DSDHYLDATF 370 380 390 400 410 420 RGGIARWINH SCDPNCESRI IKLNGRFAVV LVAIKDINPC EELTYDYKLP YEPEDKAIKC 430 440 450 460 470 480 LCGSPNCRGW LNRDKNTLDD KTFSEVKFKN ISEDVLLRLV ENNILPIDLF KADGEFYVSH IDKDGN

References

[1]

"Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis." Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q., Wortman J.R., Bidwell S.L., Alsmark U.C.M., Besteiro S., Sicheritz-Ponten T., Noel C.J., Dacks J.B., Foster P.G., Simillion C., Van de Peer Y., Miranda-Saavedra D., Barton G.J. , Westrop G.D., Mueller S., Dessi D., Fiori P.L., Ren Q., Paulsen I., Zhang H., Bastida-Corcuera F.D., Simoes-Barbosa A., Brown M.T., Hayes R.D., Mukherjee M., Okumura C.Y., Schneider R., Smith A.J., Vanacova S., Villalvazo M., Haas B.J., Pertea M., Feldblyum T.V., Utterback T.R., Shu C.L., Osoegawa K., de Jong P.J., Hrdy I., Horvathova L., Zubacova Z., Dolezal P., Malik S.B., Logsdon J.M. Jr., Henze K., Gupta A., Wang C.C., Dunne R.L., Upcroft J.A., Upcroft P., White O., Salzberg S.L., Tang P., Chiu C.-H., Lee Y.-S., Embley T.M., Coombs G.H., Mottram J.C., Tachezy J., Fraser-Liggett C.M., Johnson P.J. Science 315:207-212(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC PRA-98 / G3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS113527 Genomic DNA. Translation: EAY02704.1.
RefSeq	XP_001314927.1. XM_001314892.1.
3D structure databases
ProteinModelPortal	A2EXA5.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4760540.
KEGG	tva:TVAG_440830.
Organism-specific databases
EuPathDB	TrichDB:TVAG_440830.
Phylogenomic databases
eggNOG	COG2940.
KO	K11422.
Family and domain databases
InterPro	IPR003616. Post-SET_dom. IPR001214. SET_dom. [Graphical view]
Pfam	PF00856. SET. 1 hit. [Graphical view]
SMART	SM00508. PostSET. 1 hit. SM00317. SET. 1 hit. [Graphical view]
PROSITE	PS50868. POST_SET. 1 hit. PS50280. SET. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2EXA5_TRIVA

Accession

Primary (citable) accession number: A2EXA5

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	February 6, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)