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A2DFX6

- A2DFX6_TRIVA

UniProt

A2DFX6 - A2DFX6_TRIVA

Protein

DNA ligase

Gene

TVAG_162990

Organism
Trichomonas vaginalis
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    ORF Names:TVAG_162990Imported
    OrganismiTrichomonas vaginalisImported
    Taxonomic identifieri5722 [NCBI]
    Taxonomic lineageiEukaryotaParabasaliaTrichomonadidaTrichomonadidaeTrichomonas
    ProteomesiUP000001542: Unassembled WGS genome

    Organism-specific databases

    EuPathDBiTrichDB:TVAG_162990.

    Interactioni

    Protein-protein interaction databases

    STRINGi5722.A2DFX6.

    Structurei

    3D structure databases

    ProteinModelPortaliA2DFX6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    KOiK10747.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2DFX6-1 [UniParc]FASTAAdd to Basket

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    MTQQGIAKFF GGKDIESTKK NAIVRKQVNV NISDFDNVFK DVEIPTVEGY    50
    NIPRDVVGYV AWNRGDPIPF TFITKMVDEL EPLTGKLEIN DLLCKYFLAI 100
    LMTTPKDIVP FVFLCLGQLR PNHEGVKINI GQESIISALG DKKVVKEKLK 150
    KEGDLSKVAQ QIRSTQKSMT SMFGKVNEAY TITGVYKEFL KMAGFQGANS 200
    DRNRTQTIQK LLTNCKPEEV KCIVRMLECK LRVGAAHESF LFALGMAFRR 250
    REYIMGMIKN NPDEEDLKDH GHLFREIYYR YPIIDEILVE FLRGSFKGAE 300
    KNINIKVGIP AMPMLAKPAK KLDEIKRRLG DGRITGEYKY DGERAQIHKN 350
    KEGKVRIFSR SAEDSTAKFA DVADIITDNV KGEQYILDSE IVAYDPEKHV 400
    ILPFQTLMNR PKKGTDTPSA IHVCVCAFDL LSYNGVSMLD EPLEKRRDKL 450
    HEIVTVVPTK LQLATYKNAS KIEDLGDFFE EAVSNRTEGL MVKTLNGRYE 500
    CGKRAMSWAK LKKDYISKEV FKGGVAEEIP PDTIDVVVIG ATYGKGKRTS 550
    VYGAFLVGVY NNVTGKVESL CFVGTGFKED DLKEFYEKLH PLEMEKCPDN 600
    VDCRPLDQDP VFFKPELVWE IQVADIQTTP TYSACWGELG EKGLTIRFGR 650
    YYRTRTDKTW EQSTSTEQLL ELYHQQFEK 679
    Length:679
    Mass (Da):77,200
    Last modified:February 20, 2007 - v1
    Checksum:iD0BDA8ADE832366C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS113196 Genomic DNA. Translation: EAY20603.1.
    RefSeqiXP_001581589.1. XM_001581539.1.

    Genome annotation databases

    GeneIDi5466150.
    KEGGitva:TVAG_162990.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS113196 Genomic DNA. Translation: EAY20603.1 .
    RefSeqi XP_001581589.1. XM_001581539.1.

    3D structure databases

    ProteinModelPortali A2DFX6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5722.A2DFX6.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 5466150.
    KEGGi tva:TVAG_162990.

    Organism-specific databases

    EuPathDBi TrichDB:TVAG_162990.

    Phylogenomic databases

    eggNOGi COG1793.
    KOi K10747.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis."
      Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q., Wortman J.R., Bidwell S.L., Alsmark U.C.M., Besteiro S., Sicheritz-Ponten T., Noel C.J., Dacks J.B., Foster P.G., Simillion C., Van de Peer Y., Miranda-Saavedra D., Barton G.J.
      , Westrop G.D., Mueller S., Dessi D., Fiori P.L., Ren Q., Paulsen I., Zhang H., Bastida-Corcuera F.D., Simoes-Barbosa A., Brown M.T., Hayes R.D., Mukherjee M., Okumura C.Y., Schneider R., Smith A.J., Vanacova S., Villalvazo M., Haas B.J., Pertea M., Feldblyum T.V., Utterback T.R., Shu C.L., Osoegawa K., de Jong P.J., Hrdy I., Horvathova L., Zubacova Z., Dolezal P., Malik S.B., Logsdon J.M. Jr., Henze K., Gupta A., Wang C.C., Dunne R.L., Upcroft J.A., Upcroft P., White O., Salzberg S.L., Tang P., Chiu C.-H., Lee Y.-S., Embley T.M., Coombs G.H., Mottram J.C., Tachezy J., Fraser-Liggett C.M., Johnson P.J.
      Science 315:207-212(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC PRA-98 / G3Imported.

    Entry informationi

    Entry nameiA2DFX6_TRIVA
    AccessioniPrimary (citable) accession number: A2DFX6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: February 20, 2007
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3