ID   A2D7F8_TRIV3            Unreviewed;       456 AA.
AC   A2D7F8;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Pre-SET motif family protein {ECO:0000313|EMBL:EAY23675.1};
GN   ORFNames=TVAG_120120 {ECO:0000313|EMBL:EAY23675.1};
OS   Trichomonas vaginalis (strain ATCC PRA-98 / G3).
OC   Eukaryota; Metamonada; Parabasalia; Trichomonadida; Trichomonadidae;
OC   Trichomonas.
OX   NCBI_TaxID=412133 {ECO:0000313|EMBL:EAY23675.1, ECO:0000313|Proteomes:UP000001542};
RN   [1] {ECO:0000313|EMBL:EAY23675.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=G3 {ECO:0000313|EMBL:EAY23675.1};
RA   Amadeo P., Zhao Q., Wortman J., Fraser-Liggett C., Carlton J.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:EAY23675.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=G3 {ECO:0000313|EMBL:EAY23675.1};
RX   PubMed=17218520; DOI=10.1126/science.1132894;
RA   Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q.,
RA   Wortman J.R., Bidwell S.L., Alsmark U.C.M., Besteiro S.,
RA   Sicheritz-Ponten T., Noel C.J., Dacks J.B., Foster P.G., Simillion C.,
RA   Van de Peer Y., Miranda-Saavedra D., Barton G.J., Westrop G.D., Mueller S.,
RA   Dessi D., Fiori P.L., Ren Q., Paulsen I., Zhang H., Bastida-Corcuera F.D.,
RA   Simoes-Barbosa A., Brown M.T., Hayes R.D., Mukherjee M., Okumura C.Y.,
RA   Schneider R., Smith A.J., Vanacova S., Villalvazo M., Haas B.J., Pertea M.,
RA   Feldblyum T.V., Utterback T.R., Shu C.L., Osoegawa K., de Jong P.J.,
RA   Hrdy I., Horvathova L., Zubacova Z., Dolezal P., Malik S.B.,
RA   Logsdon J.M. Jr., Henze K., Gupta A., Wang C.C., Dunne R.L., Upcroft J.A.,
RA   Upcroft P., White O., Salzberg S.L., Tang P., Chiu C.-H., Lee Y.-S.,
RA   Embley T.M., Coombs G.H., Mottram J.C., Tachezy J., Fraser-Liggett C.M.,
RA   Johnson P.J.;
RT   "Draft genome sequence of the sexually transmitted pathogen Trichomonas
RT   vaginalis.";
RL   Science 315:207-212(2007).
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DR   EMBL; DS113177; EAY23675.1; -; Genomic_DNA.
DR   RefSeq; XP_001276923.1; XM_001276922.1.
DR   AlphaFoldDB; A2D7F8; -.
DR   STRING; 5722.A2D7F8; -.
DR   GeneID; 4720641; -.
DR   KEGG; tva:TVAG_2v0993030; -.
DR   VEuPathDB; TrichDB:TVAG_120120; -.
DR   VEuPathDB; TrichDB:TVAGG3_0993030; -.
DR   eggNOG; KOG1082; Eukaryota.
DR   InParanoid; A2D7F8; -.
DR   Proteomes; UP000001542; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0003690; F:double-stranded DNA binding; IBA:GO_Central.
DR   GO; GO:0042054; F:histone methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd10538; SET_SETDB-like; 1.
DR   Gene3D; 2.170.270.10; SET domain; 1.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   PANTHER; PTHR45660; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   PANTHER; PTHR45660:SF13; HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001542};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          238..303
FT                   /note="Pre-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50867"
FT   DOMAIN          304..433
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
FT   DOMAIN          440..456
FT                   /note="Post-SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50868"
SQ   SEQUENCE   456 AA;  51749 MW;  D78AD76B14519355 CRC64;
     MIPDFPLVFP SVPECFEKCK TLTAFTKCIK PLPPEIQSFL QLKLCSPYFT RLRIKAGESQ
     EIPITAPLQE VFSCFEICHP EYHANLAAGI AIMTGIPIDF IIDEMGLEID QKKLIIMRAL
     CKSTLGKTIA AVFTDDDRIE PIDSREYIPA TYNWTLEGNP FQDIPEESRD FIKECTKKQM
     PPDFNLSFKF TQDLSNGFNK QHGIVSVPCI NEDDDNWPRK MKWIANLEFP DMISSHYVGC
     DCHQHDCLTC HAIFNGQPIM KYTEAGRLDL ESFRSNYKPI IIECNSSCSC DSETCKNRVV
     DRKAKIHLLV CRCISKGGWG VRALEFIPKG TFICEYLGDL ITDPDKAESQ GKIYDKSGES
     YLFDLDGYGI NDKEMLTVDP KVTGNVSKFI NHNCDPNIIT IIIGTVNSEQ YHRIGFFALR
     DIYPFEDLGF HYGYKMHKID QKACNCGSLT CGGRLT
//