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Protein

Homeobox protein Hox-D4

Gene

HOXD4

Organism
Ateles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi154 – 213HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Homeobox protein Hox-D4
Gene namesi
Name:HOXD4
OrganismiAteles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey)
Taxonomic identifieri9509 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniAtelidaeAtelinaeAteles

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002854321 – 255Homeobox protein Hox-D4Add BLAST255

Structurei

3D structure databases

ProteinModelPortaliA2D4P8
SMRiA2D4P8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi133 – 138Antp-type hexapeptide6

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi222 – 234Poly-SerAdd BLAST13

Sequence similaritiesi

Keywords - Domaini

Homeobox

Phylogenomic databases

HOVERGENiHBG016849

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017995 Homeobox_antennapedia
IPR001827 Homeobox_Antennapedia_CS
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00025 ANTENNAPEDIA
PR00024 HOMEOBOX
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00032 ANTENNAPEDIA, 1 hit
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

A2D4P8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVMSSYMVNS KYVDPKFPPC EEYLQGGYLG EQGTDYYGGG AQGADFQPPG
60 70 80 90 100
LYPRPDFGEQ PFGGGGPGTR SALPARGHGQ EPGGPGGHYA APGEPCPAPP
110 120 130 140 150
APPPAPLPGA RACSQSDPKQ PPPGTALKQP AVVYPWMKKV HVNSVNPNYT
160 170 180 190 200
GGEPKRSRTA YTRQQVLELE KEFHFNRYLT RRRRIEIAHT LCLSERQIKI
210 220 230 240 250
WFQNRRMKWK KDHKLPNTKG RSSSSSSSSS CSSSTAPSQH LQPMAKDHHT

DLTTL
Length:255
Mass (Da):27,940
Last modified:February 20, 2007 - v1
Checksum:iDEB715A4D6AEDC71
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DQ976588 Genomic DNA Translation: ABM65895.1

Similar proteinsi

Entry informationi

Entry nameiHXD4_ATEGE
AccessioniPrimary (citable) accession number: A2D4P8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: February 20, 2007
Last modified: January 31, 2018
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program