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A2CI50 (ODPB_CHLAT) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismChlorokybus atmophyticus (Soil alga)
Taxonomic identifier3144 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaChlorokybophyceaeChlorokybalesChlorokybaceaeChlorokybus

Protein attributes

Sequence length335 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate By similarity.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 335335Pyruvate dehydrogenase E1 component subunit beta
PRO_0000280103

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
A2CI50 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: E846941B42AF42AF

FASTA33536,680
        10         20         30         40         50         60 
MAVRFLFEAL QKAIDEEMER EKRVVLIGED IGHYGGSYKV TQGLYGKYGK HRVIDTPIAE 

        70         80         90        100        110        120 
YSFVGAAVGA AATGLIPVVE GMNMAFILLA YSQISNNMGM LCATSGGHFQ VPMVLRGPGG 

       130        140        150        160        170        180 
IGKQLGAEHS QRLESYFQSV PGLQIVTCST PYNAKGLLKS AIRSKNPILF IEHVLLYNLK 

       190        200        210        220        230        240 
GEVPDNDYLL PLEKAELVRE GSDITVLTYS RQRYNVIQAV KVLVEEGYDP EVIDLISLKP 

       250        260        270        280        290        300 
FDMETIGKSI QKTHKVLIVE ECMMTGGISN VLQSLIIDNF FDALDAAPLI LSSPNVPTPY 

       310        320        330 
TGPLEEATVV QTIDIIESIE YGITGKPPKP RTAKK 

« Hide

References

[1]"A clade uniting the green algae Mesostigma viride and Chlorokybus atmophyticus represents the deepest branch of the Streptophyta in chloroplast genome-based phylogenies."
Lemieux C., Otis C., Turmel M.
BMC Biol. 5:2-2(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SAG 48.80.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
DQ422812 Genomic DNA. Translation: ABM87959.1.
RefSeqYP_001019115.1. NC_008822.1.

3D structure databases

ProteinModelPortalA2CI50.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4783272.

Phylogenomic databases

ProtClustDBCHL00144.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
InterProIPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_CHLAT
AccessionPrimary (citable) accession number: A2CI50
Entry history
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: February 20, 2007
Last modified: October 16, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program