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Protein
Submitted name:

Histone-lysine N-methyltransferase EHMT2

Gene

Ehmt2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Histone-lysine N-methyltransferase EHMT2Imported
Gene namesi
Name:Ehmt2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:2148922. Ehmt2.

Subcellular locationi

  • Chromosome SAAS annotation
  • Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

ChromosomeSAAS annotation, NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PaxDbiA2CG76.
PRIDEiA2CG76.

Expressioni

Gene expression databases

BgeeiA2CG76.
ExpressionAtlasiA2CG76. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000013931.

Structurei

3D structure databases

ProteinModelPortaliA2CG76.
SMRiA2CG76. Positions 638-927, 941-1211.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini673 – 906234ANK_REP_REGIONInterPro annotationAdd
BLAST
Domaini991 – 105464Pre-SETInterPro annotationAdd
BLAST
Domaini1057 – 1174118SETInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili336 – 38348Sequence analysisAdd
BLAST

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 pre-SET domain.UniRule annotation
Contains 5 ANK repeats.UniRule annotation

Keywords - Domaini

ANK repeatUniRule annotation, Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1082. Eukaryota.
COG0666. LUCA.
COG2940. LUCA.
GeneTreeiENSGT00780000121845.
HOGENOMiHOG000231216.
HOVERGENiHBG028394.
KOiK11420.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF12796. Ank_2. 3 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2CG76-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGLPRGRGL MRARGRGRAA PTGGRGRGRG GAHRGRGRPR SLLSLPRAQA
60 70 80 90 100
SWAPQLPAGL TGPPVPCLPS QGEAPAEMGA LLLEKEPRGA AERVHSSLGD
110 120 130 140 150
TPQSEETLPK ANPDSLEPAG PSSPASVTVT VGDEGADTPV GAASLIGDEP
160 170 180 190 200
ESLEGDGGRI VLGHATKSFP SSPSKGGACP SRAKMSMTGA GKSPPSVQSL
210 220 230 240 250
AMRLLSMPGA QGAATAGPEP SPATTAAQEG QPKVHRARKT MSKPSNGQPP
260 270 280 290 300
IPEKRPPEVQ HFRMSDDMHL GKVTSDVAKR RKLNSGSLSE DLGSAGGSGD
310 320 330 340 350
IILEKGEPRP LEEWETVVGD DFSLYYDAYS VDERVDSDSK SEVEALAEQL
360 370 380 390 400
SEEEEEEEEE EEEEEEEEEE EEEEEEDEES GNQSDRSGSS GRRKAKKKWR
410 420 430 440 450
KDSPWVKPSR KRRKREPPRA KEPRGVSNDT SSLETERGFE ELPLCSCRME
460 470 480 490 500
APKIDRISER AGHKCMATES VDGELLGCNA AILKRETMRP SSRVALMVLC
510 520 530 540 550
EAHRARMVKH HCCPGCGYFC TAGTFLECHP DFRVAHRFHK ACVSQLNGMV
560 570 580 590 600
FCPHCGEDAS EAQEVTIPRG DGGTPPIGTA APALPPLAHD APGRADTSQP
610 620 630 640 650
SARMRGHGEP RRPPCDPLAD TIDSSGPSLT LPNGGCLSAV GLPPGPGREA
660 670 680 690 700
LEKALVIQES ERRKKLRFHP RQLYLSVKQG ELQKVILMLL DNLDPNFQSD
710 720 730 740 750
QQSKRTPLHA AAQKGSVEIC HVLLQAGANI NAVDKQQRTP LMEAVVNNHL
760 770 780 790 800
EVARYMVQLG GCVYSKEEDG STCLHHAAKI GNLEMVSLLL STGQVDVNAQ
810 820 830 840 850
DSGGWTPIIW AAEHKHIDVI RMLLTRGADV TLTDNEENIC LHWASFTGSA
860 870 880 890 900
AIAEVLLNAQ CDLHAVNYHG DTPLHIAARE SYHDCVLLFL SRGANPELRN
910 920 930 940 950
KEGDTAWDLT PERSDVWFAL QLNRKLRLGV GNRAVRTEKI ICRDVARGYE
960 970 980 990 1000
NVPIPCVNGV DGEPCPEDYK YISENCETST MNIDRNITHL QHCTCVDDCS
1010 1020 1030 1040 1050
SSNCLCGQLS IRCWYDKDGR LLQEFNKIEP PLIFECNQAC SCWRSCKNRV
1060 1070 1080 1090 1100
VQSGIKVRLQ LYRTAKMGWG VRALQTIPQG TFICEYVGEL ISDAEADVRE
1110 1120 1130 1140 1150
DDSYLFDLDN KDGEVYCIDA RYYGNISRFI NHLCDPNIIP VRVFMLHQDL
1160 1170 1180 1190 1200
RFPRIAFFSS RDIRTGEELG FDYGDRFWDI KSKYFTCQCG SEKCKHSAEA
1210 1220
IALEQSRLAR LDPHPELLPD LSSLPPINT
Length:1,229
Mass (Da):134,688
Last modified:February 20, 2007 - v1
Checksum:i7314CD378299EA9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT025759 Genomic DNA. No translation available.
RefSeqiNP_001273502.1. NM_001286573.1.
UniGeneiMm.35345.

Genome annotation databases

EnsembliENSMUST00000097342; ENSMUSP00000094955; ENSMUSG00000013787.
GeneIDi110147.
KEGGimmu:110147.
UCSCiuc008cee.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT025759 Genomic DNA. No translation available.
RefSeqiNP_001273502.1. NM_001286573.1.
UniGeneiMm.35345.

3D structure databases

ProteinModelPortaliA2CG76.
SMRiA2CG76. Positions 638-927, 941-1211.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000013931.

Proteomic databases

PaxDbiA2CG76.
PRIDEiA2CG76.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000097342; ENSMUSP00000094955; ENSMUSG00000013787.
GeneIDi110147.
KEGGimmu:110147.
UCSCiuc008cee.3. mouse.

Organism-specific databases

CTDi10919.
MGIiMGI:2148922. Ehmt2.

Phylogenomic databases

eggNOGiKOG1082. Eukaryota.
COG0666. LUCA.
COG2940. LUCA.
GeneTreeiENSGT00780000121845.
HOGENOMiHOG000231216.
HOVERGENiHBG028394.
KOiK11420.

Miscellaneous databases

NextBioi35544411.
SOURCEiSearch...

Gene expression databases

BgeeiA2CG76.
ExpressionAtlasiA2CG76. baseline and differential.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR007728. Pre-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF12796. Ank_2. 3 hits.
PF05033. Pre-SET. 1 hit.
PF00856. SET. 1 hit.
[Graphical view]
PRINTSiPR01415. ANKYRIN.
SMARTiSM00248. ANK. 6 hits.
SM00468. PreSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 5 hits.
PS50867. PRE_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiA2CG76_MOUSE
AccessioniPrimary (citable) accession number: A2CG76
Entry historyi
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 11, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.