Sequence length	233 AA.
Sequence status	Fragment.
Protein existence	Predicted.

Keywords
Biological process	Transcription Transcription regulation Spearmint SPM003619
Cellular component	Nucleus Spearmint SPM003619
Gene Ontology (GO)
Biological process	SMAD protein complex assembly Inferred from electronic annotation. Source: Compara activation of caspase activity Inferred from electronic annotation. Source: Compara activation of pro-apoptotic gene products Inferred from electronic annotation. Source: Compara cell cycle arrest Inferred from electronic annotation. Source: Compara cell-cell junction organization Inferred from electronic annotation. Source: Compara evasion of host defenses by virus Inferred from electronic annotation. Source: Compara induction of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of apoptosis Inferred from electronic annotation. Source: Compara negative regulation of cell growth Inferred from electronic annotation. Source: Compara negative regulation of cell proliferation Inferred from electronic annotation. Source: Compara negative regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara negative regulation of mitotic cell cycle Inferred from electronic annotation. Source: Compara positive regulation of alkaline phosphatase activity Inferred from electronic annotation. Source: Compara positive regulation of bone mineralization Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of epithelial to mesenchymal transition Inferred from electronic annotation. Source: Compara positive regulation of focal adhesion assembly Inferred from electronic annotation. Source: Compara positive regulation of gene-specific transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara positive regulation of interleukin-1 beta production Inferred from electronic annotation. Source: Compara positive regulation of positive chemotaxis Inferred from electronic annotation. Source: Compara positive regulation of stress fiber assembly Inferred from electronic annotation. Source: Compara positive regulation of transcription factor import into nucleus Inferred from electronic annotation. Source: Compara positive regulation of transforming growth factor-beta3 production Inferred from electronic annotation. Source: Compara regulation of transforming growth factor-beta2 production Inferred from electronic annotation. Source: Compara release of cytochrome c from mitochondria Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara transcription Inferred from electronic annotation. Source: UniProtKB-KW transdifferentiation Inferred from electronic annotation. Source: Compara transforming growth factor beta receptor signaling pathway Inferred from electronic annotation. Source: InterPro transport Inferred from electronic annotation. Source: Compara
Cellular component	receptor complex Inferred from electronic annotation. Source: Compara transcription factor complex Inferred from electronic annotation. Source: InterPro
Molecular function	R-SMAD binding Inferred from electronic annotation. Source: Compara co-SMAD binding Inferred from electronic annotation. Source: Compara ligand-regulated transcription factor activity Inferred from electronic annotation. Source: Compara promoter binding Inferred from electronic annotation. Source: Compara protein homodimerization activity Inferred from electronic annotation. Source: Compara specific transcriptional repressor activity Inferred from electronic annotation. Source: Compara transcription factor activity Inferred from electronic annotation. Source: InterPro transforming growth factor beta receptor binding Inferred from electronic annotation. Source: Compara transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity Inferred from electronic annotation. Source: Compara ubiquitin protein ligase binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

[1]	Sycamore N. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Sequence databases
EMBL GenBank DDBJ	CT010509 Genomic DNA. Translation: CAM26527.1.
IPI	IPI00831542.
UniGene	Mm.7320
3D structure databases
SMR	A2CG44. Positions 2-67, 155-233.
ModBase	Search...
Protein-protein interaction databases
STRING	A2CG44.
Proteomic databases
PRIDE	A2CG44.
Genome annotation databases
Ensembl	ENSMUST00000034973; ENSMUSP00000034973; ENSMUSG00000032402; Mus musculus. [Genome view] ENSMUST00000113931; ENSMUSP00000109564; ENSMUSG00000032402; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:1201674. Smad3.
Phylogenomic databases
eggNOG	roNOG13959.
HOVERGEN	A2CG44.
InParanoid	A2CG44.
Gene expression databases
Bgee	A2CG44.
Genevestigator	A2CG44.
Family and domain databases
InterPro	IPR013790. Dwarfin. IPR003619. MAD_homology1_Dwarfin-type. IPR013019. MAD_homology_MH1. IPR017855. SMAD_dom-like. IPR001132. SMAD_dom_Dwarfin-type. IPR008984. SMAD_FHA_domain. [Graphical view]
Gene3D	G3DSA:3.90.520.10. MAD_MH1. 1 hit. G3DSA:2.60.200.10. MH2_Dwarfin-type. 1 hit.
PANTHER	PTHR13703. Dwarfin. 1 hit.
Pfam	PF03165. MH1. 1 hit. PF03166. MH2. 1 hit. [Graphical view]
SMART	SM00523. DWA. 1 hit. [Graphical view]
PROSITE	PS51075. MH1. 1 hit. PS51076. MH2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Names and origin

Protein attributes

Ontologies

Sequence annotation (Features)

Experimental info

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other Resources

Entry information