A2CEW4 (A2CEW4_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase EMBL CAM13027.1 Ensembl ENSDARP00000024082

Gene names

Name:	atic Ensembl ENSDARP00000024082 ZFIN ZDB-GENE-011212-4
ORF Names:	CH211-172N16.2-001 EMBL CAM13027.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAM13027.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	590 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Hydrolase EMBL CAM13027.1 Transferase EMBL CAM13027.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	purine nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	IMP cyclohydrolase activity Inferred from electronic annotation. Source: InterPro phosphoribosylaminoimidazolecarboxamide formyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2CEW4 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 22DA7FE447D6CDC5	FASTA	590	64,057
	10 20 30 40 50 60 MASEIALLSV SDKTGLVEFA RRLVSVGLSL VASGGTAKTL RDAGLAVRDV SEITGFPEML 70 80 90 100 110 120 GGRVKTLHPA VHGGILARQT PSDNADMEKL GFSLVRVAVC NLYPFVKTVS SPGVTVEDAV 130 140 150 160 170 180 EQIDIGGVTL LRAAAKNHAR VTVVCDPSDY NVVAKEMETS EIHDTTMETR KTLALKAFTH 190 200 210 220 230 240 TAQYDEAISD YFRREYSRGV SQLPLRYGMN PHQAPAQLYT TRPALPLTVL NGSPGFINLC 250 260 270 280 290 300 DALNAWQLVR ELRKALGLPA ATSFKHVSPA GAAVGVPLSE DEAKVCMVND MLQDLTPLAT 310 320 330 340 350 360 AYARARGSDR MSSFGDFIAL SDVCDVPTAK IISREVSDGI VAPGYEEDAL RILSKKKNGN 370 380 390 400 410 420 YCVLKMDPEY EPDEEEVRVL FGLHLKQKRN GAVIDKELFS NIVSKGKLSE SALRDLIVAS 430 440 450 460 470 480 IAVKYTQSNS VCYAKDGQVI GIGAGQQSRI HCTRLAGDKA DNWWLRHHPG VLSMRFRGGV 490 500 510 520 530 540 KRAEMANAID LYVSGTVGEG PDKEVWKGLF EEVPEPLSEV EKKNWISSLQ AVALSSDAFF 550 560 570 580 590 PFRDNVDRAK QSGVEYIAAP SGSTADEVVV KACNELGITL VHTNIRLFHH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Dunn M. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000024082.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000024082.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR762428 Genomic DNA. Translation: CAM13027.1.
IPI	IPI00501402.
UniGene	Dr.481.
3D structure databases
ProteinModelPortal	A2CEW4.
SMR	A2CEW4. Positions 4-590.
ModBase	Search...
Protein-protein interaction databases
STRING	A2CEW4.
Proteomic databases
PRIDE	A2CEW4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000022307; ENSDARP00000024082; ENSDARG00000016706.
Organism-specific databases
ZFIN	ZDB-GENE-011212-4. atic.
Phylogenomic databases
eggNOG	fiNOG08674.
HOGENOM	HBG498048.
HOVERGEN	HBG006912.
OMA	FTGTRHF.
OrthoDB	EOG43BMNG.
PhylomeDB	A2CEW4.
Gene expression databases
Bgee	A2CEW4.
Family and domain databases
InterPro	IPR024051. AICAR_Tfase_dom. IPR024050. AICAR_Tfase_insert_dom. IPR002695. AICARFT_IMPCHas. IPR016193. Cytidine_deaminase-like. IPR011607. MGS-like_dom. [Graphical view]
Gene3D	G3DSA:1.10.287.440. G3DSA:1.10.287.440. 1 hit. G3DSA:3.40.140.20. G3DSA:3.40.140.20. 3 hits. G3DSA:3.40.50.1380. MGS-like_dom. 1 hit.
PANTHER	PTHR11692. AICARFT_IMPCHas. 1 hit.
Pfam	PF01808. AICARFT_IMPCHas. 1 hit. PF02142. MGS. 1 hit. [Graphical view]
PIRSF	PIRSF000414. AICARFT_IMPCHas. 1 hit.
SMART	SM00798. AICARFT_IMPCHas. 1 hit. SM00851. MGS. 1 hit. [Graphical view]
SUPFAM	SSF53927. Cytidine_deaminase-like. 1 hit. SSF52335. MGS-like_dom. 1 hit.
TIGRFAMs	TIGR00355. PurH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2CEW4_DANRE

Accession

Primary (citable) accession number: A2CEW4

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	January 25, 2012
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)