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Protein
Submitted name:

Ankle2 protein

Gene

ankle2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-DRE-2995383 Initiation of Nuclear Envelope Reformation

Names & Taxonomyi

Protein namesi
Submitted name:
Ankle2 proteinImported
Submitted name:
Ankyrin repeat and LEM domain-containing 2Imported
Gene namesi
Name:ankle2Imported
Synonyms:si:dkey-215k6.5Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-030131-6090 ankle2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSDARG00000035607

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000117092

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 49LEMInterPro annotationAdd BLAST45

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili381 – 401Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IE4A Eukaryota
ENOG410XRMS LUCA
GeneTreeiENSGT00390000016767
HOGENOMiHOG000234326
HOVERGENiHBG096073
KOiK21412
OrthoDBiEOG091G05GX
TreeFamiTF317729

Family and domain databases

CDDicd00204 ANK, 1 hit
cd12944 LEM_ANKL2, 1 hit
Gene3Di1.10.720.40, 1 hit
1.25.40.20, 1 hit
3.40.970.10, 1 hit
InterProiView protein in InterPro
IPR035007 ANKLE2
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR011015 LEM/LEM-like_dom_sf
IPR035006 LEM_ANKL2
IPR003887 LEM_dom
IPR011320 RNase_H1_N
IPR037056 RNase_H1_N_sf
PANTHERiPTHR12349:SF4 PTHR12349:SF4, 1 hit
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF01693 Cauli_VI, 1 hit
PF03020 LEM, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 2 hits
SM00540 LEM, 1 hit
SUPFAMiSSF48403 SSF48403, 2 hits
SSF63451 SSF63451, 1 hit
PROSITEiView protein in PROSITE
PS50954 LEM, 1 hit

Sequencei

Sequence statusi: Complete.

A2CEB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAVLSRLKG LTADELREEI IKANLKCGPI TATTRAIFER KLARALVESA
60 70 80 90 100
GLTEPDASGD NSATLDRSVV PSSAASATPD AITGEDGDFG YGMGLNPPEE
110 120 130 140 150
EALSGTVCAC NVENTQTPSK TAQVSPTFYG VCPLWEDVLA RNERAHVYTD
160 170 180 190 200
KKEALQAVKM MKGARFKAFS NREDAEKFAK GICDYYPSPS KSTPCVSPVK
210 220 230 240 250
PGLVFSKDHP SMIEADTINR EKANSFKSPR TQDLTAKLRK AVEKGDELGF
260 270 280 290 300
TELVWSNPRY LIGSGDNPTV VQEGCRYNVM HVAAKENQPG IVQILLDTLE
310 320 330 340 350
NPEFMRLMYP DDLESMLQKR IRYIVDLYLN TPDKAGFETP LHFACKFGCP
360 370 380 390 400
EVVNILCSHP DIDKNCKNKY NQKPCEVICE RMKEKGKVQE VKQKINEYLE
410 420 430 440 450
ERLYIPLLRA TDNSSQAVIG APWSPEPMES LSPWLPRSPK DPVMAVRAFA
460 470 480 490 500
GPLSPSKADE FRRAWKTPPR ERADHFHNIL KSDPDRGAER VGRDLAHELG
510 520 530 540 550
HPWAEYWDFL DSFVDLQSTE GLKMLEEYLS KKDFRERAHE EAGENETSNR
560 570 580 590 600
FKTPSPGKLK KFCNSISVGA FLDEGDDISL EEIKNRQNAA LTSISSVCSK
610 620 630 640 650
DGLQGAVGGL EFHILPVSHS ADLIEAAAEQ DLLLSEKSMI SSSKNGLCEQ
660 670 680 690 700
GSGDRTPNGD KVSPRICGSS NSCMLSPISN LMAEFERMSL LDEPDRTNRE
710 720 730 740 750
RRRSGGKRQT TELTSGLGRL SLSSEDDSVF EKDRTSALRA AENDGTERRN
760 770 780 790 800
EVDVRSSASS DEYFLASERL EPINQQTIDT SGCERMICAR SKSWDHGGRD
810 820 830 840 850
LSSSGSSSSY RSLDSSQDFI LRTPPRVTKG LFIEGDSPTK LDREVLSALG
860 870 880 890 900
VSDFDPLKFP SIHKWKSTIQ TYSQSEMQSW LTPAVHKSHL RALSATPGSP
910 920 930 940 950
VSGLMSPVSR FSPARHMGSP DNCSPGRYSP AHSTYSPAHP NYSPVSYIQR
960
IRLKHFGDTP I
Length:961
Mass (Da):106,381
Last modified:February 20, 2007 - v1
Checksum:i4D3A61E29448E143
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388061 Genomic DNA No translation available.
BC163479 mRNA Translation: AAI63479.1
RefSeqiNP_001119867.1, NM_001126395.2
XP_005165137.1, XM_005165080.3
UniGeneiDr.34529

Genome annotation databases

EnsembliENSDART00000145210; ENSDARP00000117092; ENSDARG00000035607
GeneIDi559297
KEGGidre:559297

Similar proteinsi

Entry informationi

Entry nameiA2CEB2_DANRE
AccessioniPrimary (citable) accession number: A2CEB2
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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