A2CD56 (A2CD56_PROM3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361
Short name=Poly(P)/ATP NAD kinase 2 HAMAP MF_00361
EC=2.7.1.23 HAMAP MF_00361

Gene names

Name:	ppnK2 HAMAP MF_00361
Ordered Locus Names:	P9303_26861

Organism

Prochlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP] EMBL ABM79416.1

Taxonomic identifier

59922 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	315 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity. HAMAP MF_00361
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity. HAMAP MF_00361
Subcellular location	Cytoplasm By similarity HAMAP MF_00361.
Sequence similarities	Belongs to the NAD kinase family. HAMAP MF_00361

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00361
Ligand	ATP-binding HAMAP MF_00361 NAD HAMAP MF_00361 NADP HAMAP MF_00361 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00361 EMBL ABM79416.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2CD56 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: A1DF7D5F9D74C69F	FASTA	315	34,069
	10 20 30 40 50 60 MRLDLVWVIY RAGSHSAHRE ACCCVDELQA LGVKVVMAMS GVTANPFPDL LASEAGLPDL 70 80 90 100 110 120 AVVLGGDGTV LGAARHLAVH DVPILSFNVG GHLGFLTHER CLLDGGQLWQ RLLQDNFALE 130 140 150 160 170 180 RRMMLQAAVD SRSPAERTAR PTASLQDLNG TKPPHWALND FYMRPYRDDV SPTCTLELEI 190 200 210 220 230 240 DGEVVDHYRG DGLILATPTG STGYSMASGG PILHPGIDAI IVSPICPMSL SSRPVIVPPA 250 260 270 280 290 300 SRLVIGLLGE NTRRVKLWKD GASGALLEPG QCCVVQRARH HALMVVLEQS PSYYRTLTHK 310 LHWAGSLLNN QPSPS

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000554 Genomic DNA. Translation: ABM79416.1.
RefSeq	YP_001018681.1. NC_008820.1.
3D structure databases
ProteinModelPortal	A2CD56.
ModBase	Search...
Protein-protein interaction databases
STRING	A2CD56.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4779002.
GenomeReviews	Gene locus P9303_26861 in contig CP000554_GR.
KEGG	pmf:P9303_26861.
PATRIC	23002935. VBIProMar17757_2751.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0061.
HOGENOM	HBG713904.
OMA	TGSTCYT.
PhylomeDB	A2CD56.
ProtClustDB	PRK02645.
Family and domain databases
HAMAP	MF_00361. NAD_kinase. [Tree]
InterPro	IPR016064. ATP-NAD_kinase_PpnK-typ. IPR017438. ATP-NAD_kinase_PpnK-typ_a/b. IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. polyP/ATP_NADK_prd. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit. G3DSA:3.40.50.10330. ATP-NAD_kinase_PpnK-typ_a/b. 1 hit.
KO	K00858.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
SUPFAM	SSF111331. ATP-NAD_kinase_PpnK-typ. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2CD56_PROM3

Accession

Primary (citable) accession number: A2CD56

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)