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A2CBH2 (MQO_PROM3) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:P9303_20971
OrganismProchlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP]
Taxonomic identifier59922 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length496 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 496496Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_1000023812

Sequences

Sequence LengthMass (Da)Tools
A2CBH2 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 0B6611DFFE7C54CF

FASTA49653,905
        10         20         30         40         50         60 
MAVSDVAGSQ SRYDAVLVGA GIMSATLAAL LHELDPELRL LMVERLQAPG LESSAAENNA 

        70         80         90        100        110        120 
GTGHAANCEL NYTPLQPDGS VATAKALAIN TAFERSLEFW ASLTEKGKLL PQQFLHLVPH 

       130        140        150        160        170        180 
ISVVFGDADL AFLHQRFQQL SALPAFASMQ WSTDAAELAE WMPLVMEGRA NAESVAATCI 

       190        200        210        220        230        240 
KRGTDVDFGL LTRAYVKSLQ ASGALELSCG CEVVHLHRLG KHRWNLDLKH SSGSRSVQTP 

       250        260        270        280        290        300 
FVFLGAGGGA LPLLQRSGIP EAAAYAGFPV SGQWLVCSEP GLTARHHAKV YGKAKVGAPP 

       310        320        330        340        350        360 
MSVPHLDSRW IDGCRSLLFG PYAGFSSKFL KQGSRLDLLR SVRRSNFRSM LEVGFKNFDL 

       370        380        390        400        410        420 
VTYLLSELQQ SEKDRFETLK QFLPNAQLND WKLSVAGQRV QIIKGTAEGG RLQMGTEVVS 

       430        440        450        460        470        480 
AEDGSLAALL GASPGASTAV TVMLEVLQRC WSERMASESW QERLQKLLPS YGHDPNSDPL 

       490 
LLMQMRIRSN ELLSFT

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9303.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000554 Genomic DNA. Translation: ABM78832.1.
RefSeqYP_001018097.1. NC_008820.1.

3D structure databases

ProteinModelPortalA2CBH2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2CBH2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4776834.
GenomeReviewsGene locus P9303_20971 in contig CP000554_GR.
KEGGpmf:P9303_20971.
PATRIC23001711. VBIProMar17757_2159.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMANTQFEVS.
PhylomeDBA2CBH2.
ProtClustDBPRK05257.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_PROM3
AccessionPrimary (citable) accession number: A2CBH2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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