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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Prochlorococcus marinus (strain MIT 9303)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei163GTPUniRule annotation1
Binding sitei167GTPUniRule annotation1
Binding sitei210GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi45 – 49GTPUniRule annotation5
Nucleotide bindingi132 – 134GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotationImported
Ordered Locus Names:P9303_19971Imported
OrganismiProchlorococcus marinus (strain MIT 9303)Imported
Taxonomic identifieri59922 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002274 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA2CB79.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 228TubulinInterPro annotationAdd BLAST192
Domaini230 – 348Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.

Sequencei

Sequence statusi: Complete.

A2CB79-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHQHLNGSAS TMEMAIKNMS MSTSMETAGI LPSQSARIEV IGVGGGGSNA
60 70 80 90 100
VNRMILSDLD GVNYRVMNTD AQALLQSAAS NRVQLGQTLT RGLGAGGNPS
110 120 130 140 150
IGQKAAEESR AELQQALQGV DLVFIAVGMG GGTGTGAAPV VAEVAKESGA
160 170 180 190 200
LTVGIVTKPF SFEGRRRMRQ AAEGIGRLAD HVDTLIVIPN DRIKDVISEA
210 220 230 240 250
PLQEAFRSAD DILRMGVKGI SDIITCPGLV NVDFADVRSV MTEAGTALLG
260 270 280 290 300
IGEGSGRSRA IEAAQAAISS PLLEAARIDG AKGCVINISG GRDMTLEDMT
310 320 330 340 350
SASEVIYDVV DPEANIIVGA VVDEKLEGEV HVTVIATGFE GNQPYRSERS
360 370 380
INKIASQSIY SQPEANESGA RIPEFLRKRQ PRNDNEI
Length:387
Mass (Da):40,586
Last modified:February 20, 2007 - v1
Checksum:i6B267F52D081E274
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000554 Genomic DNA. Translation: ABM78739.1.

Genome annotation databases

EnsemblBacteriaiABM78739; ABM78739; P9303_19971.
KEGGipmf:P9303_19971.

Similar proteinsi

Entry informationi

Entry nameiA2CB79_PROM3
AccessioniPrimary (citable) accession number: A2CB79
Entry historyiIntegrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: September 27, 2017
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported