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A2CAR9 (GLGB_PROM3) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:P9303_18371
OrganismProchlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP]
Taxonomic identifier59922 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length756 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7567561,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_1000044990

Sites

Active site4311Nucleophile By similarity
Active site4841Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A2CAR9 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: A2E8EA9D0B967F29

FASTA75687,734
        10         20         30         40         50         60 
MTTSVALDWV VQDGQRLAEC RHDHPFSLLG PQSHEGQWIV RIWMPEASQV ELLCDGRTTA 

        70         80         90        100        110        120 
MTTPNHSWIF EAALNQDPGR TYQLRVKRAG IVHEQHDPWA FHDEWMGEMD RHLFAEGNHH 

       130        140        150        160        170        180 
HIWQRMGAHL MEREGVEGVM FCLWAPRACS VAVLGELNGW DGRHHPMQRR QGGLWELFIP 

       190        200        210        220        230        240 
GFKEGTLYKY EIRTQDGHCY QKADPYGFQH EVRPATSSVV ARLDRYQWQD EQWMRQRDSR 

       250        260        270        280        290        300 
NALDQPISVY EMHLGSWIHA ATDEPYIELD GTPRAPVLAA DMKPGARLLT YPELADQLIP 

       310        320        330        340        350        360 
YVKDRGFTHI ELMPISEHPF DGSWGYQVTG WYAPTSRFGS PDEFRAFVDR CHAEGLGVII 

       370        380        390        400        410        420 
DWVPGHFPKD GHGLAFFDGT HLYEHSDPRI GEHKEWGTLI FNYSRNEVRN FLVANLVYWF 

       430        440        450        460        470        480 
EQFHIDGIRV DAVASMLYRD YLRPDGEWIA NEDGGRENTE AVRFLQQANH VLFQHFPGAL 

       490        500        510        520        530        540 
SIAEESTTWP MVTQPTDMGG LGFNLKWNMG WMHDMLDYFE LDPWFRQFHQ NNITFSIWYT 

       550        560        570        580        590        600 
YTENFMLALS HDEVVHGKSN LLHKMPGDDW QKCANVRALL AYMWTHPGKK TIFMGMEFGQ 

       610        620        630        640        650        660 
RSEWNVWGDL QWELLTHDPH KGLQKLVDDL NTFYKAEPAL WKDDFDQYGF QWIDCNDNRH 

       670        680        690        700        710        720 
SIISFMRRES SGGTWLVVVA NFTPQSHSNY RIGVPIGGYY EEVFNTDSSC YGGRNLGNMG 

       730        740        750 
GKNTDEFNIH GYEQSLELCL PALSVLVFRH DPKRSL 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: MIT 9303.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000554 Genomic DNA. Translation: ABM78579.1.
RefSeqYP_001017844.1. NC_008820.1.

3D structure databases

ProteinModelPortalA2CAR9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING59922.P9303_18371.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM78579; ABM78579; P9303_18371.
GeneID4776112.
KEGGpmf:P9303_18371.
PATRIC23001165. VBIProMar17757_1891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAAKLLFMG.
OrthoDBEOG6JX7GT.

Enzyme and pathway databases

BioCycPMAR59922:GH54-1936-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_PROM3
AccessionPrimary (citable) accession number: A2CAR9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries