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A2C9U6 (A2C9U6_PROM3) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-acetyl-gamma-glutamyl-phosphate reductase HAMAP MF_00150

Short name=AGPR HAMAP MF_00150
EC=1.2.1.38 HAMAP MF_00150
Alternative name(s):
N-acetyl-glutamate semialdehyde dehydrogenase HAMAP MF_00150
Gene names
Name:argC HAMAP MF_00150
Ordered Locus Names:P9303_15121
OrganismProchlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP] EMBL ABM78256.1
Taxonomic identifier59922 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchlorophytesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH. HAMAP MF_00150 SAAS SAAS023013

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4. HAMAP MF_00150 SAAS SAAS023013

Subcellular location

Cytoplasm By similarity HAMAP MF_00150 SAAS SAAS023013.

Sequence similarities

Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. HAMAP MF_00150

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1741 By similarity HAMAP MF_00150

Sequences

Sequence LengthMass (Da)Tools
A2C9U6 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 5A778E9DEBC32EC6

FASTA37140,497
        10         20         30         40         50         60 
MKAMESTHRS PASDISQVRG SRVAVIGATG YGGLQTIRLL EDHPQLHVTY LGGERSAGRR 

        70         80         90        100        110        120 
WSELCPFLPI PDDPEVQSPD PDKIAEYADY AVLSLPNGLA SQLAPQLLKR NVRVVDLSAD 

       130        140        150        160        170        180 
FRYRSLEQWK QVYVHEAQNL NRDDVQLCRE AVYGLPEWKG PEIAVANLVA APGCFPTASL 

       190        200        210        220        230        240 
LPLLPFLKQG LIENDGLIID AKTGTSGGGR VAKEQFLLSE ASESIMPYGV VGHRHTSEIE 

       250        260        270        280        290        300 
QLASEVAGQP IELQFTPHLV PMVRGLLATV YGRLRDPGLT AEDCTTVLKA VYRHHPCIDV 

       310        320        330        340        350        360 
LPVGTYPATK WVKYSNKAVL SVQVDNRNSR LILMSAVDNL IKGQAGQGVQ CLNLMAGLPP 

       370 
TTGMSLLTFY P 

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References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000554 Genomic DNA. Translation: ABM78256.1.
RefSeqYP_001017521.1. NC_008820.1.

3D structure databases

ProteinModelPortalA2C9U6.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2C9U6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4777902.
GenomeReviewsGene locus P9303_15121 in contig CP000554_GR.
KEGGpmf:P9303_15121.
PATRIC23000502. VBIProMar17757_1562.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0002.
HOGENOMHBG294213.
OMATAEDCTT.
PhylomeDBA2C9U6.
ProtClustDBPRK00436.

Family and domain databases

HAMAPMF_00150. ArgC_type1.
[Tree]
InterProIPR023013. AGPR_AS.
IPR000706. AGPR_type-1.
IPR016040. NAD(P)-bd_dom.
IPR000534. Semialdehyde_DH_NAD-bd.
IPR012280. Semialdhyde_DH_dimer_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KOK00145.
PfamPF01118. Semialdhyde_dh. 1 hit.
PF02774. Semialdhyde_dhC. 1 hit.
[Graphical view]
SMARTSM00859. Semialdhyde_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR01850. ArgC. 1 hit.
PROSITEPS01224. ARGC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2C9U6_PROM3
AccessionPrimary (citable) accession number: A2C9U6
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: January 25, 2012
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)