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A2C6Y0 (A2C6Y0_PROM3) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine dehydrogenase PIRNR PIRNR000183
EC=1.4.1.1 PIRNR PIRNR000183
Gene names
Name:ald EMBL ABM77240.1
Ordered Locus Names:P9303_04881
OrganismProchlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP] EMBL ABM77240.1
Taxonomic identifier59922 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length379 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH. PIRNR PIRNR000183

Pathway

Amino-acid degradation; L-alanine degradation via dehydrogenase pathway; NH(3) and pyruvate from L-alanine: step 1/1. PIRNR PIRNR000183

Sequence similarities

Belongs to the AlaDH/PNT family. PIRNR PIRNR000183

Ontologies

Keywords
   LigandNAD PIRNR PIRNR000183
   Molecular functionOxidoreductase PIRNR PIRNR000183 EMBL ABM77240.1
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionalanine dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
A2C6Y0 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 8679A244FDF5DA74

FASTA37939,629
        10         20         30         40         50         60 
MDSSILSAPI ASIGVPTEIK ADELRVALTP DGVKELVNKG LEVRVQAGAG AGAGIGDEAF 

        70         80         90        100        110        120 
ADAGAKLVNR EEAWAAHLVV KVKEPQEEEF CLLRQDMVLF TYLHLAAYPK VGEALLNAGT 

       130        140        150        160        170        180 
TGVGYETVQL ENGSLPLLAP MSEIAGRLAA QVGAHLLERP HGGRGVLIGG CTGVQPARVV 

       190        200        210        220        230        240 
VLGAGTVGWN AARLAAAMDA EVMLLDRSPE RLRSLETSRR GRLISVVNSR GLLERLIPTA 

       250        260        270        280        290        300 
DLLIGAVLTP GGRAPTLVDE EMVKQMKPNS VIVDVAIDQG GCVATSQETT HTHPTVTIHG 

       310        320        330        340        350        360 
VQHYAVGNMP GAVPFTSTEA LVSVTLPYIL GIAGRGLEEA VTERPELLSG LNTIQGSVCH 

       370 
PGVAKALGLP PRHPMACLR

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References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000554 Genomic DNA. Translation: ABM77240.1.
RefSeqYP_001016505.1. NC_008820.1.

3D structure databases

ProteinModelPortalA2C6Y0.
SMRA2C6Y0. Positions 12-379.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2C6Y0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4777215.
GenomeReviewsGene locus P9303_04881 in contig CP000554_GR.
KEGGpmf:P9303_04881.
PATRIC22998403. VBIProMar17757_0525.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0686.
HOGENOMHBG289735.
OMAVAHGHEV.
PhylomeDBA2C6Y0.
ProtClustDBCLSK825419.

Family and domain databases

InterProIPR008141. Ala_DH/Pyr_transHydgase.
IPR007886. AlaDH/PNT_N.
IPR007698. AlaDH/PNT_NAD(H)-bd.
[Graphical view]
KOK00259.
PANTHERPTHR10160:SF3. PTHR10160:SF3. 1 hit.
PfamPF01262. AlaDh_PNT_C. 1 hit.
PF05222. AlaDh_PNT_N. 1 hit.
[Graphical view]
PIRSFPIRSF000183. Alanine_dh. 1 hit.
SMARTSM01002. AlaDh_PNT_C. 1 hit.
SM01003. AlaDh_PNT_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00518. AlaDH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2C6Y0_PROM3
AccessionPrimary (citable) accession number: A2C6Y0
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: January 25, 2012
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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