A2C6S4 (RPIA_PROM3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	P9303_04321

Organism

Prochlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP]

Taxonomic identifier

59922 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	238 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 238	238	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_1000016958

Sequences

	Sequence		Length	Mass (Da)
	A2C6S4 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 602874EAA05114F1	FASTA	238	24,992
	10 20 30 40 50 60 MADLQTQMKQ AVAAAAVEQI KDGMVLGLGS GSTAALMIQA LGAKLASGEL REIVGVTTSF 70 80 90 100 110 120 QGEVMAAELG IPLRNLTAVD RIDLAIDGAD EVDPSFQLIK GGGACHVQEK LVASRADRFV 130 140 150 160 170 180 VVVDSTKIVD RLNLGFLLPV EVLPGAWRQV QGRLAELGGI ADLRMAQCKA GPVVTDQGNL 190 200 210 220 230 VLDVSMAGGI GDPEDLECRI NNLPGVLENG LFVNLTDEVL VGQISDGVAG VRRLQRRE

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: MIT 9303.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000554 Genomic DNA. Translation: ABM77184.1.
RefSeq	YP_001016449.1. NC_008820.1.
3D structure databases
ProteinModelPortal	A2C6S4.
ModBase	Search...
Protein-protein interaction databases
STRING	A2C6S4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4776210.
GenomeReviews	Gene locus P9303_04321 in contig CP000554_GR.
KEGG	pmf:P9303_04321.
PATRIC	22998281. VBIProMar17757_0464.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	A2C6S4.
ProtClustDB	PRK00702.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_PROM3

Accession

Primary (citable) accession number: A2C6S4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program