A2C6G7 (A2C6G7_PROM3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide methionine sulfoxide reductase MsrB HAMAP MF_01400
EC=1.8.4.12 HAMAP MF_01400

Alternative name(s):
Peptide-methionine (R)-S-oxide reductase HAMAP MF_01400

Gene names

Name:	msrB HAMAP MF_01400
Ordered Locus Names:	P9303_03241

Organism

Prochlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP] EMBL ABM77077.1

Taxonomic identifier

59922 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin. HAMAP MF_01400
Cofactor	Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein By similarity. HAMAP MF_01400
Sequence similarities	Belongs to the MsrB Met sulfoxide reductase family. HAMAP MF_01400

Ontologies

Keywords
Ligand	Metal-binding HAMAP MF_01400 Zinc HAMAP MF_01400
Molecular function	Oxidoreductase HAMAP MF_01400 SAAS SAAS002579 EMBL ABM77077.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	peptide-methionine (R)-S-oxide reductase activity Inferred from electronic annotation. Source: EC peptide-methionine-(S)-S-oxide reductase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	130	1	Nucleophile By similarity HAMAP MF_01400
	Metal binding	58	1	Zinc By similarity HAMAP MF_01400
	Metal binding	61	1	Zinc By similarity HAMAP MF_01400
	Metal binding	107	1	Zinc By similarity HAMAP MF_01400
	Metal binding	110	1	Zinc By similarity HAMAP MF_01400

Sequences

	Sequence		Length	Mass (Da)
	A2C6G7 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 13C6270479EC90D8	FASTA	144	15,654
	10 20 30 40 50 60 MSRSDSSASD SVDWIKLSPE EWQARLTREQ YQVARKGGTE RAFTGAYWNH KAAGMYCCVC 70 80 90 100 110 120 CGAPLFSSAT KFDSGTGWPS FSDGVKAGAI TTHRDTSHGM ERTEINCSRC GAHLGHVFND 130 140 GPAPTGQRYC VNSASLDFSE QSEV

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000554 Genomic DNA. Translation: ABM77077.1.
RefSeq	YP_001016342.1. NC_008820.1.
3D structure databases
ProteinModelPortal	A2C6G7.
ModBase	Search...
Protein-protein interaction databases
STRING	A2C6G7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4779004.
GenomeReviews	Gene locus P9303_03241 in contig CP000554_GR.
KEGG	pmf:P9303_03241.
PATRIC	22998023. VBIProMar17757_0336.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0229.
HOGENOM	HBG715255.
OMA	APLFRSD.
PhylomeDB	A2C6G7.
ProtClustDB	CLSK647284.
Family and domain databases
HAMAP	MF_01400. MsrB. [Tree]
InterPro	IPR002579. Methionine_sulphoxide_MsrB. IPR011057. Mss4-like. [Graphical view]
Gene3D	G3DSA:2.170.150.20. MsrB. 1 hit.
KO	K07305.
Pfam	PF01641. SelR. 1 hit. [Graphical view]
SUPFAM	SSF51316. Mss4_like. 1 hit.
TIGRFAMs	TIGR00357. TIGR00357. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A2C6G7_PROM3

Accession

Primary (citable) accession number: A2C6G7

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)