Skip Header

Contribute Send feedback
Read comments (?) or add your own

A2C6F2 (A2C6F2_PROM3) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Peptide deformylase 1 HAMAP MF_00163
Short name=PDF 1 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163
Alternative name(s):
Polypeptide deformylase 1 HAMAP MF_00163
Gene names
Name:def EMBL ABM77062.1
Synonyms:def1 HAMAP MF_00163
Ordered Locus Names:P9303_03091
OrganismProchlorococcus marinus (strain MIT 9303) [Complete proteome] [HAMAP] EMBL ABM77062.1
Taxonomic identifier59922 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length201 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163

Catalytic activity

Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181

Cofactor

Binds 1 Fe2+ ion By similarity. HAMAP MF_00163

Sequence similarities

Belongs to the polypeptide deformylase family. HAMAP MF_00163

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1641 By similarity HAMAP MF_00163
Metal binding1211Iron By similarity HAMAP MF_00163
Metal binding1631Iron By similarity HAMAP MF_00163
Metal binding1671Iron By similarity HAMAP MF_00163

Sequences

Sequence LengthMass (Da)Tools
A2C6F2 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: F8E336410A3AEC3E

FASTA20122,311
        10         20         30         40         50         60 
MARSFAQLAR TAEKTKGSVA VPKEPLDHPP LQIHTLGNGV LRQSTRRIGK VDESVRDLVR 

        70         80         90        100        110        120 
DMLRSMYAAK GIGLAAPQVG IHKQLLVLDL DLETPTTPPV VLINPEIISS SATVETYEEG 

       130        140        150        160        170        180 
CLSIPGVYLN VVRPSEIVLS FRDEMGRPRK MKADGLMARC IQHEMDHLEG VLFVDRVTDE 

       190        200 
NELSLELKEH GFKRADVRPL V

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000554 Genomic DNA. Translation: ABM77062.1.
RefSeqYP_001016327.1. NC_008820.1.

3D structure databases

ProteinModelPortalA2C6F2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2C6F2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4777581.
GenomeReviewsGene locus P9303_03091 in contig CP000554_GR.
KEGGpmf:P9303_03091.
PATRIC22997989. VBIProMar17757_0320.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0242.
HOGENOMHBG665227.
OMAGVLFVDY.
PhylomeDBA2C6F2.
ProtClustDBPRK00150.

Family and domain databases

HAMAPMF_00163. Pep_deformylase.
[Tree]
InterProIPR000181. Fmet_deformylase.
IPR023635. Peptide_deformylase.
[Graphical view]
Gene3DG3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KOK01462.
PANTHERPTHR10458. Fmet_deformylase. 1 hit.
PfamPF01327. Pep_deformylase. 1 hit.
[Graphical view]
PIRSFPIRSF004749. Pep_def. 1 hit.
PRINTSPR01576. PDEFORMYLASE.
SUPFAMSSF56420. Fmet_deformylase. 1 hit.
TIGRFAMsTIGR00079. Pept_deformyl. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2C6F2_PROM3
AccessionPrimary (citable) accession number: A2C6F2
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: December 14, 2011
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info