SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

A2C535

- PUR5_PROM1

UniProt

A2C535 - PUR5_PROM1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, NATL1_20391
Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR167555:GI3K-2084-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:NATL1_20391
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002592: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 346346Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_1000046454Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi167555.NATL1_20391.

Structurei

3D structure databases

ProteinModelPortaliA2C535.
SMRiA2C535. Positions 1-335.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

A2C535-1 [UniParc]FASTAAdd to Basket

« Hide

MDYKTAGVDV TAGRAFVERI KSCVEKTHKS EVIGGLGGFG GCIRIPKGFE    50
SPVLVSGTDG VGTKLELAQQ YGCHFGVGID LVAMCVNDVI TNGARPLFFL 100
DYIASGTLTP DALAEVIEGI AAGCCQSDCS LLGGETAEMP GFYPSGRYDL 150
AGFCVGIVEN HHLIDGTKIN CGDQIIGIKS NGVHSNGFSL VRKVLSMANV 200
DENTLYGKDK RNLIQSLLEP TAIYVQLVEK LLRENLPIHG MTHITGGGLP 250
ENLPRIFPSG LLPHIDITTW EITEIFNWLQ NAGDIPEIDL WNTFNMGIGF 300
CLIVPKNEVN SALEICMKND FEAWNIGQVV ESQNNSKHSG ILGIPS 346
Length:346
Mass (Da):37,255
Last modified:February 20, 2007 - v1
Checksum:i55F2D29468FBB178
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM76595.1.
RefSeqiWP_011824545.1. NC_008819.1.
YP_001015859.1. NC_008819.1.

Genome annotation databases

EnsemblBacteriaiABM76595; ABM76595; NATL1_20391.
GeneIDi4779866.
KEGGipme:NATL1_20391.
PATRICi23021741. VBIProMar31285_2081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM76595.1 .
RefSeqi WP_011824545.1. NC_008819.1.
YP_001015859.1. NC_008819.1.

3D structure databases

ProteinModelPortali A2C535.
SMRi A2C535. Positions 1-335.
ModBasei Search...

Protein-protein interaction databases

STRINGi 167555.NATL1_20391.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM76595 ; ABM76595 ; NATL1_20391 .
GeneIDi 4779866.
KEGGi pme:NATL1_20391.
PATRICi 23021741. VBIProMar31285_2081.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci PMAR167555:GI3K-2084-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL1A.

Entry informationi

Entry nameiPUR5_PROM1
AccessioniPrimary (citable) accession number: A2C535
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi