A2C4N6 (RPIA_PROM1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	NATL1_18901

Organism

Prochlorococcus marinus (strain NATL1A) [Complete proteome] [HAMAP]

Taxonomic identifier

167555 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Prochlorales › Prochlorococcaceae › Prochlorococcus › Prochlorococcus marinus

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP-Rule MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP-Rule MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Ribose-5-phosphate isomerase A HAMAP-Rule MF_00170		PRO_1000194714

Sequences

	Sequence		Length	Mass (Da)
	A2C4N6 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: D02934273135A20B	FASTA	236	25,092
	10 20 30 40 50 60 MDLQNQMKKA VAQAAVDQIQ NGMILGLGSG STAALMIEAL AIKIKSGEIK DVVGVTTSFQ 70 80 90 100 110 120 GEVLASELGI PLKSLSSVSE IDLAIDGADE VDPKFQLIKG GGACHVQEKL VAALAKKFIV 130 140 150 160 170 180 VVDSTKLVEK LNLDFKLPVE VLPSAWKQVQ KTLINLGGEG NLRMAQKKAG PIVTDQGNLI 190 200 210 220 230 LDLTFRNGID QPELLETQIN NIPGVLENGL FVNLTDEVLV GKVESDVVGV ESLKKI

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NATL1A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000553 Genomic DNA. Translation: ABM76446.1.
RefSeq	YP_001015710.1. NC_008819.1.
3D structure databases
ProteinModelPortal	A2C4N6.
ModBase	Search...
Protein-protein interaction databases
STRING	167555.NATL1_18901.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABM76446; ABM76446; NATL1_18901.
GeneID	4779199.
KEGG	pme:NATL1_18901.
PATRIC	23021429. VBIProMar31285_1929.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HOG000276369.
KO	K01807.
OMA	STTAYFI.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	PMAR167555:GI3K-1939-MONOMER.
UniPathway	UPA00115; UER00412.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A.
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. PTHR11934. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_PROM1

Accession

Primary (citable) accession number: A2C4N6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 20, 2007
Last modified:	May 1, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program