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Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription

Enzyme and pathway databases

BioCyciPMAR167555:G1G7Z-1719-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:NATL1_18861
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002592 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003003731 – 1095DNA-directed RNA polymerase subunit betaAdd BLAST1095

Proteomic databases

PRIDEiA2C4N2

Interactioni

Subunit structurei

In cyanobacteria the RNAP catalytic core is composed of 2 alpha, 1 beta, 1 beta', 1 gamma and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Protein-protein interaction databases

STRINGi167555.NATL1_18861

Structurei

3D structure databases

ProteinModelPortaliA2C4N2
SMRiA2C4N2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108IIJ Bacteria
COG0085 LUCA
HOGENOMiHOG000218611
KOiK03043
OMAiFMTWEGY
OrthoDBiPOG091H01MI

Family and domain databases

CDDicd00653 RNA_pol_B_RPB2, 1 hit
Gene3Di2.40.270.10, 2 hits
2.40.50.150, 1 hit
3.90.1110.10, 1 hit
HAMAPiMF_01321 RNApol_bact_RpoB, 1 hit
InterProiView protein in InterPro
IPR019462 DNA-dir_RNA_pol_bsu_external_1
IPR015712 DNA-dir_RNA_pol_su2
IPR007120 DNA-dir_RNAP_su2_dom
IPR037033 DNA-dir_RNAP_su2_hyb_sf
IPR010243 RNA_pol_bsu_bac
IPR007121 RNA_pol_bsu_CS
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR037034 RNA_pol_Rpb2_2_sf
IPR007645 RNA_pol_Rpb2_3
IPR007641 RNA_pol_Rpb2_7
IPR014724 RNA_pol_RPB2_OB-fold
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 1 hit
PF04565 RNA_pol_Rpb2_3, 1 hit
PF10385 RNA_pol_Rpb2_45, 1 hit
PF00562 RNA_pol_Rpb2_6, 1 hit
PF04560 RNA_pol_Rpb2_7, 1 hit
TIGRFAMsiTIGR02013 rpoB, 1 hit
PROSITEiView protein in PROSITE
PS01166 RNA_POL_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

A2C4N2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRSAIQVAK AATYLPDLVE VQRSSFKWFL DKGLIEELDN FSPITDYTGK
60 70 80 90 100
LELHFIGAEY KLKRPRHDVE EAKRRDATFA SQMYVTCRLV NKETGEIKEQ
110 120 130 140 150
EVFIGELPLM TERGTFIING AERVIVNQIV RSPGVYFKDE QDKNGRRTYN
160 170 180 190 200
ASVIPNRGAW LKFETDKNDL LHVRVDKTRK INAHVLMRAM GLSDNDVIDK
210 220 230 240 250
LRHPEFYKKS IDAANEEGIS SEDQALLELY KKLRPGEPPS VSGGQQLLQT
260 270 280 290 300
RFFDPKRYDL GRVGRYKINK KLRLTIPDNL RTLTNEDVLS TLDYLINLEL
310 320 330 340 350
DVGGATLDDI DHLGNRRVRS VGELLQNQVR VGLNRLERII KERMTVGETD
360 370 380 390 400
SLTPAQLVNP KPLVAAIKEF FGSSQLSQFM DQTNPLAELT HKRRISALGP
410 420 430 440 450
GGLTRERAGF AVRDIHPSHY GRLCPIETPE GPNAGLINSL ATHARVNEYG
460 470 480 490 500
FIETPFWKVE NGRLIKEGDP IYLSADLEDE CRVAPGDVAT NEEGKIMAEL
510 520 530 540 550
VPVRYRQDFE TVSPEQVDYV QLSPVQVISV AASLIPFLEH DDANRALMGS
560 570 580 590 600
NMQRQAVPLL RPERPLVGTG LETQVARDSG MVPISKVNGT VSYVDANAIV
610 620 630 640 650
VTDDEGNDHT HYLQKYQRSN QDTCLNHRPI VFNGDPVIVG QVLADGSACE
660 670 680 690 700
GGEIALGQNV LIAYMPWEGY NYEDAILVSE RLVKDDLYTS VHIEKYEIEA
710 720 730 740 750
RQTKLGPEEI TREIPNVSEE NLGNLDEMGI IRIGAYVESG DILVGKVTPK
760 770 780 790 800
GESDQPPEEK LLRAIFGEKA RDVRDNSLRV PSTERGRVVD VRIYTREQGD
810 820 830 840 850
ELPPGANMVV RVYVAQRRKI QVGDKMAGRH GNKGIISRIL PREDMPYLPD
860 870 880 890 900
GTPVDICLNP LGVPSRMNVG QVFELLMGWA ASNLDCRVKI VPFDEMYGPE
910 920 930 940 950
MSNQTVQAYL KEAAKQPGKS WVYNPKDPGK LLLKDGRTGE PFDQPVAVGY
960 970 980 990 1000
AHFLKLVHLV DDKIHARSTG PYSLVTQQPL GGKAQQGGQR LGEMEVWALE
1010 1020 1030 1040 1050
AYGAAYTLQE LLTVKSDDMQ GRNEALNSIV KGKPIPRPGT PESFKVLMRE
1060 1070 1080 1090
LQSLGLDIGV YTDDGKEVDL MQDVNPRRST PSRPTYESLG KEYEE
Length:1,095
Mass (Da):122,570
Last modified:February 20, 2007 - v1
Checksum:i607B1E495FA0FD90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000553 Genomic DNA Translation: ABM76442.1
RefSeqiWP_011824421.1, NC_008819.1

Genome annotation databases

EnsemblBacteriaiABM76442; ABM76442; NATL1_18861
KEGGipme:NATL1_18861

Similar proteinsi

Entry informationi

Entry nameiRPOB_PROM1
AccessioniPrimary (citable) accession number: A2C4N2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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