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A2C2A9 (A2C2A9_PROM1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydrodipicolinate reductase HAMAP MF_00102
Short name=DHPR HAMAP MF_00102
EC=1.3.1.26 HAMAP MF_00102
Gene names
Name:dapB HAMAP MF_00102
Ordered Locus Names:NATL1_10611
OrganismProchlorococcus marinus (strain NATL1A) [Complete proteome] [HAMAP] EMBL ABM75619.1
Taxonomic identifier167555 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length282 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-2,3,4,5-tetrahydrodipicolinate + NAD(P)+ = (S)-2,3-dihydrodipicolinate + NAD(P)H. HAMAP MF_00102

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 4/4. HAMAP MF_00102

Subcellular location

Cytoplasm By similarity HAMAP MF_00102.

Sequence similarities

Belongs to the dihydrodipicolinate reductase family. HAMAP MF_00102

Sequences

Sequence LengthMass (Da)Tools
A2C2A9 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: 176CA03FD5CE28D2

FASTA28230,287
        10         20         30         40         50         60 
MSSANQSIPV LVAGALGRMG SEVVKAINSS KDFQLVGAID NQKDKEGQDI GSLLGLGELD 

        70         80         90        100        110        120 
VFLSSDFEGS LCAASQNVPK NGSNNGAVLV DFTHPKFAYK HTRTSIAYGV HPVIGTTGIT 

       130        140        150        160        170        180 
AEQLDDLSKF ADKASLGSAI IPNFSVGMVL LQQAAAAAAR FYEFAELTEM HHNKKADAPS 

       190        200        210        220        230        240 
GTCIKTAELI EEQRSNFNRS FVEEEESIKG SRGGLRASGL RLHSVRLPGL VAHQQVMFGS 

       250        260        270        280 
NGETYELSHN TIDRSAYMPG VLLVVKKIRS FNKLVYGLEK IL

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000553 Genomic DNA. Translation: ABM75619.1.
RefSeqYP_001014884.1. NC_008819.1.

3D structure databases

ProteinModelPortalA2C2A9.
ModBaseSearch...

Protein-protein interaction databases

STRINGA2C2A9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4780264.
GenomeReviewsGene locus NATL1_10611 in contig CP000553_GR.
KEGGpme:NATL1_10611.
PATRIC23019719. VBIProMar31285_1085.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0289.
HOGENOMHBG594002.
OMADRASFMP.
PhylomeDBA2C2A9.
ProtClustDBPRK00048.

Enzyme and pathway databases

BioCycPMAR167555:NATL1_10611-MONOMER.

Family and domain databases

HAMAPMF_00102. DapB.
[Tree]
InterProIPR022663. DapB_C.
IPR000846. DapB_N.
IPR022664. DapB_N_CS.
IPR011770. Dihydrodipicolinate_Rdtase.
IPR023940. Dihydrodipicolinate_Rdtase_bac.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 2 hits.
KOK00215.
PANTHERPTHR20836. DapB_bac/pln. 1 hit.
PfamPF05173. DapB_C. 1 hit.
PF01113. DapB_N. 1 hit.
[Graphical view]
PIRSFPIRSF000161. DHPR. 1 hit.
TIGRFAMsTIGR00036. DapB. 1 hit.
PROSITEPS01298. DAPB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA2C2A9_PROM1
AccessionPrimary (citable) accession number: A2C2A9
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: December 14, 2011
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info