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A2C1U2 (A2C1U2_PROM1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 28. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:pnil34 EMBL ABM75452.1
Synonyms:acsF HAMAP MF_01840
Ordered Locus Names:NATL1_08941
OrganismProchlorococcus marinus (strain NATL1A) [Complete proteome] [HAMAP] EMBL ABM75452.1
Taxonomic identifier167555 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
A2C1U2 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: CC74CA2AE41D673F

FASTA36742,926
        10         20         30         40         50         60 
MTATASSPKL RVDTRGTNEL PPHLDENLLT PRFYVTEFKK AAKTELTDAR EEFEAMLSEM 

        70         80         90        100        110        120 
KADYNCTHFD RKASLDRLQE LPQKAKETYE SYLVRSVISE FSGFLLFKEI SNRLKKEGNR 

       130        140        150        160        170        180 
DLGKLFQFLA RDEARHAGFL SRALVAEGIE VDLPHLGGKR AATWFPISWV IYSVYLSEKI 

       190        200        210        220        230        240 
GYWRYILMDR HLKANPDQAF APLFDFFEPW CQDENRHGDC FTVMMRCWPG ITKGFRGKLL 

       250        260        270        280        290        300 
SRFFLWSVFL THTLTVCERG EFYELLGIDP KEFDEEVIKR TNHTSKNAFP WVFNLDDNKF 

       310        320        330        340        350        360 
WDLRNKIIES FRAFVGAKGL TKPVKFVKFA TLIFKQFALP MEKTNALRYD KNVNFTGQDI 


LNFWTDK

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000553 Genomic DNA. Translation: ABM75452.1.
RefSeqYP_001014717.1. NC_008819.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGA2C1U2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID4779103.
GenomeReviewsGene locus NATL1_08941 in contig CP000553_GR.
KEGGpme:NATL1_08941.
PATRIC23019375. VBIProMar31285_0916.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMANRHGDIF.
PhylomeDBA2C1U2.
ProtClustDBPRK13654.

Enzyme and pathway databases

BioCycPMAR167555:NATL1_08941-MONOMER.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR012347. Ferritin-rel.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
Gene3DG3DSA:1.20.1260.10. Ferritin_rel. 1 hit.
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameA2C1U2_PROM1
AccessionPrimary (citable) accession number: A2C1U2
Entry history
Integrated into UniProtKB/TrEMBL: February 20, 2007
Last sequence update: February 20, 2007
Last modified: December 14, 2011
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info