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A2C073

- TRMB_PROM1

UniProt

A2C073 - TRMB_PROM1

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Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, NATL1_03191
Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351S-adenosyl-L-methionine By similarity
Binding sitei60 – 601S-adenosyl-L-methionine By similarity
Binding sitei87 – 871S-adenosyl-L-methionine By similarity
Active sitei113 – 1131 By similarity
Binding sitei113 – 1131S-adenosyl-L-methionine By similarity
Binding sitei117 – 1171Substrate By similarity
Binding sitei149 – 1491Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPMAR167555:GI3K-324-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:NATL1_03191
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002592: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000288201Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi167555.NATL1_03191.

Structurei

3D structure databases

ProteinModelPortaliA2C073.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000237936.
KOiK03439.
OMAiVIQPEFI.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2C073-1 [UniParc]FASTAAdd to Basket

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MRQHVNPLSQ FFQLPLSLPS KNILFEKSHY PIHLDIGSAK GEFLIELATK    50
YPDWNFVGLE IREPLVSLCE KKRRKLELTN LKFLFCNVNV SLDEWLSDLD 100
FGQLKRVSIQ FPDPWFKRKH FKRRVLNTNI LNSIAKSMSK DGEIFIQSDI 150
LKLIEYMTNT IDENRYFTRK NVGDLRSIDK NPYDVMTDRE IFSLKKNLLI 200
YRVMYIRNSL LFTN 214
Length:214
Mass (Da):25,428
Last modified:February 20, 2007 - v1
Checksum:iB0C47492FBE79584
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74883.1.
RefSeqiYP_001014148.1. NC_008819.1.

Genome annotation databases

EnsemblBacteriaiABM74883; ABM74883; NATL1_03191.
GeneIDi4780488.
KEGGipme:NATL1_03191.
PATRICi23018163. VBIProMar31285_0326.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74883.1 .
RefSeqi YP_001014148.1. NC_008819.1.

3D structure databases

ProteinModelPortali A2C073.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167555.NATL1_03191.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM74883 ; ABM74883 ; NATL1_03191 .
GeneIDi 4780488.
KEGGi pme:NATL1_03191.
PATRICi 23018163. VBIProMar31285_0326.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000237936.
KOi K03439.
OMAi VIQPEFI.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci PMAR167555:GI3K-324-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL1A.

Entry informationi

Entry nameiTRMB_PROM1
AccessioniPrimary (citable) accession number: A2C073
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: February 20, 2007
Last modified: June 11, 2014
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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