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A2C066

- PYRB_PROM1

UniProt

A2C066 - PYRB_PROM1

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Protein

Aspartate carbamoyltransferase

Gene
pyrB, NATL1_03121
Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Carbamoyl phosphate + L-aspartate = phosphate + N-carbamoyl-L-aspartate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. amino acid binding Source: InterPro
  2. aspartate carbamoyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
  2. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  3. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciPMAR167555:GI3K-316-MONOMER.
UniPathwayiUPA00070; UER00116.

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate carbamoyltransferase (EC:2.1.3.2)
Alternative name(s):
Aspartate transcarbamylase
Short name:
ATCase
Gene namesi
Name:pyrB
Ordered Locus Names:NATL1_03121
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002592: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 339339Aspartate carbamoyltransferaseUniRule annotationPRO_0000301605Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi167555.NATL1_03121.

Structurei

3D structure databases

ProteinModelPortaliA2C066.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATCase/OTCase family.

Phylogenomic databases

eggNOGiCOG0540.
HOGENOMiHOG000022685.
KOiK00609.
OMAiMTLNAMR.
OrthoDBiEOG61KBJZ.

Family and domain databases

Gene3Di3.40.50.1370. 2 hits.
HAMAPiMF_00001. Asp_carb_tr.
InterProiIPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view]
PfamiPF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view]
PRINTSiPR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMiSSF53671. SSF53671. 1 hit.
TIGRFAMsiTIGR00670. asp_carb_tr. 1 hit.
PROSITEiPS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2C066-1 [UniParc]FASTAAdd to Basket

« Hide

MNNWKHNHVL DLSTFSLEDY KTVLELTTRF KDVHKSSSKK LPALHGRLIA    50
NLFFEPSTRT RTSFELAAKR LSADVQNFSV SSSSLSKGET PLDTILTYIS 100
MGADILVIRH ESTNVPAELA NYVDINNINT SILNAGDGFH SHPSQGLLDL 150
FTLATFFNPN EPSTNSLLNK KITIVGDILH SRVARSNLWA LTACGAEVTL 200
CGPPSLLPEE FIDFVQNPRL GQNFDPINKR GSVFIKRSLK DALKNSDAVM 250
TLRLQKERMK QNMLKDLDSY YAQYGITHES LKWCEKKVPV LHPGPVNRGV 300
EISNRLVEDN SINLISKQVE NGIPTRMALL YLLGLNKKD 339
Length:339
Mass (Da):37,947
Last modified:February 20, 2007 - v1
Checksum:iCC29BB14BDF7FA99
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74876.1.
RefSeqiYP_001014141.1. NC_008819.1.

Genome annotation databases

EnsemblBacteriaiABM74876; ABM74876; NATL1_03121.
GeneIDi4780421.
KEGGipme:NATL1_03121.
PATRICi23018145. VBIProMar31285_0318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74876.1 .
RefSeqi YP_001014141.1. NC_008819.1.

3D structure databases

ProteinModelPortali A2C066.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167555.NATL1_03121.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM74876 ; ABM74876 ; NATL1_03121 .
GeneIDi 4780421.
KEGGi pme:NATL1_03121.
PATRICi 23018145. VBIProMar31285_0318.

Phylogenomic databases

eggNOGi COG0540.
HOGENOMi HOG000022685.
KOi K00609.
OMAi MTLNAMR.
OrthoDBi EOG61KBJZ.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00116 .
BioCyci PMAR167555:GI3K-316-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1370. 2 hits.
HAMAPi MF_00001. Asp_carb_tr.
InterProi IPR006132. Asp/Orn_carbamoyltranf_P-bd.
IPR006130. Asp/Orn_carbamoylTrfase.
IPR002082. Asp_carbamoyltransf.
IPR006131. Asp_carbamoyltransf_Asp/Orn-bd.
[Graphical view ]
Pfami PF00185. OTCace. 1 hit.
PF02729. OTCace_N. 1 hit.
[Graphical view ]
PRINTSi PR00100. AOTCASE.
PR00101. ATCASE.
SUPFAMi SSF53671. SSF53671. 1 hit.
TIGRFAMsi TIGR00670. asp_carb_tr. 1 hit.
PROSITEi PS00097. CARBAMOYLTRANSFERASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL1A.

Entry informationi

Entry nameiPYRB_PROM1
AccessioniPrimary (citable) accession number: A2C066
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: February 20, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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