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A2C058

- AROC_PROM1

UniProt

A2C058 - AROC_PROM1

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Protein

Chorismate synthase

Gene

aroC

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.UniRule annotation

Cofactori

Reduced flavin.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. chorismate synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis

Enzyme and pathway databases

BioCyciPMAR167555:GI3K-308-MONOMER.
UniPathwayiUPA00053; UER00090.

Names & Taxonomyi

Protein namesi
Recommended name:
Chorismate synthaseUniRule annotation (EC:4.2.3.5UniRule annotation)
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyaseUniRule annotation
Gene namesi
Name:aroCUniRule annotation
Ordered Locus Names:NATL1_03041
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002592: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Chorismate synthasePRO_1000022522Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi167555.NATL1_03041.

Structurei

3D structure databases

ProteinModelPortaliA2C058.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chorismate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0082.
HOGENOMiHOG000060335.
KOiK01736.
OMAiYMRDLKK.
OrthoDBiEOG6WDSHT.

Family and domain databases

Gene3Di3.60.150.10. 1 hit.
HAMAPiMF_00300. Chorismate_synth.
InterProiIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
PANTHERiPTHR21085. PTHR21085. 1 hit.
PfamiPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFiPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMiSSF103263. SSF103263. 1 hit.
TIGRFAMsiTIGR00033. aroC. 1 hit.
PROSITEiPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2C058-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGSSFGKLFT ISTFGESHGG GVGVIIDGCP PRLELDINEI QNDLNRRRPG
60 70 80 90 100
QSKITTPRNE SDEVEILSGL LGNKTLGTPI AMVVRNKDHR PKDYSEIKKT
110 120 130 140 150
FRPSHADATY QKKYGIQASS GGGRASARET IGRVAAGSVA KQLLTKFAKT
160 170 180 190 200
EILAWVKRIH DIEAEIHPSE VTFDEIEKNI VRCPNQSAAD LMIQRVEAFG
210 220 230 240 250
KEGDSCGGVI ECVVRNPPIG LGMPVFDKLE ADLAKALMSL PATKGFEVGS
260 270 280 290 300
GFGGTYLKGS EHNDPFLPSD SNQLKTATNN SGGIQGGISN GEDIVLRVGF
310 320 330 340 350
KPTATIRKSQ KTIDEDGNAI TLKATGRHDP CVLPRAVPMV EAMVALVLAD
360
HLLRQRGQCT D
Length:361
Mass (Da):38,830
Last modified:February 20, 2007 - v1
Checksum:iA98EB58BE0EE5EBA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74868.1.
RefSeqiWP_011823079.1. NC_008819.1.
YP_001014133.1. NC_008819.1.

Genome annotation databases

EnsemblBacteriaiABM74868; ABM74868; NATL1_03041.
GeneIDi4780216.
KEGGipme:NATL1_03041.
PATRICi23018129. VBIProMar31285_0310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74868.1 .
RefSeqi WP_011823079.1. NC_008819.1.
YP_001014133.1. NC_008819.1.

3D structure databases

ProteinModelPortali A2C058.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167555.NATL1_03041.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM74868 ; ABM74868 ; NATL1_03041 .
GeneIDi 4780216.
KEGGi pme:NATL1_03041.
PATRICi 23018129. VBIProMar31285_0310.

Phylogenomic databases

eggNOGi COG0082.
HOGENOMi HOG000060335.
KOi K01736.
OMAi YMRDLKK.
OrthoDBi EOG6WDSHT.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00090 .
BioCyci PMAR167555:GI3K-308-MONOMER.

Family and domain databases

Gene3Di 3.60.150.10. 1 hit.
HAMAPi MF_00300. Chorismate_synth.
InterProi IPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view ]
PANTHERi PTHR21085. PTHR21085. 1 hit.
Pfami PF01264. Chorismate_synt. 1 hit.
[Graphical view ]
PIRSFi PIRSF001456. Chorismate_synth. 1 hit.
SUPFAMi SSF103263. SSF103263. 1 hit.
TIGRFAMsi TIGR00033. aroC. 1 hit.
PROSITEi PS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL1A.

Entry informationi

Entry nameiAROC_PROM1
AccessioniPrimary (citable) accession number: A2C058
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3