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A2C025

- PGK_PROM1

UniProt

A2C025 - PGK_PROM1

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401SubstrateUniRule annotation
Binding sitei122 – 1221SubstrateUniRule annotation
Binding sitei155 – 1551SubstrateUniRule annotation
Binding sitei206 – 2061ATPUniRule annotation
Binding sitei297 – 2971ATP; via carbonyl oxygenUniRule annotation
Binding sitei328 – 3281ATPUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR167555:GI3K-275-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:pgkUniRule annotation
Ordered Locus Names:NATL1_02711
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002592: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 401401Phosphoglycerate kinasePRO_1000058026Add
BLAST

Proteomic databases

PRIDEiA2C025.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi167555.NATL1_02711.

Structurei

3D structure databases

ProteinModelPortaliA2C025.
SMRiA2C025. Positions 1-400.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingUniRule annotation
Regioni63 – 664Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiWEALDIG.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2C025-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKRSLSSLG AEDLCGKRVL VRVDFNVPLG DEGQITDDTR IRAALPTIND
60 70 80 90 100
LLDKSARVIL SAHFGRPKGE VNETMRLTAV AQRLSELLGK TVVKTESCIG
110 120 130 140 150
AEAKSKVDAM SNGDVVLLEN VRFISGEEKN DTEFAKELAS LAEVYVNDAF
160 170 180 190 200
GAAHRAHAST EGVTKFLSPC VAGYLMEKEL KYLQGAIDQP KSPLAAIVGG
210 220 230 240 250
SKVSSKIGVL ESLIDKCDKI IVGGGMIFTF YKARGLSVGN SLVEEDKLEL
260 270 280 290 300
ASALEKKAKE KGVEFLLPTD VVLADNFSPD ANSKLSKVDA ISEGWMGLDI
310 320 330 340 350
GSESVELFQN ALKDCKTVIW NGPMGVFEFE KFANGTNAIA NTLAELSAQG
360 370 380 390 400
CCTIIGGGDS VAAVEKAGLA KNMSHISTGG GASLELLEGK VLPGVSALDD

A
Length:401
Mass (Da):42,361
Last modified:February 20, 2007 - v1
Checksum:i51F9B4ABB7B99EE5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74835.1.
RefSeqiWP_011823052.1. NC_008819.1.
YP_001014100.1. NC_008819.1.

Genome annotation databases

EnsemblBacteriaiABM74835; ABM74835; NATL1_02711.
GeneIDi4779905.
KEGGipme:NATL1_02711.
PATRICi23018063. VBIProMar31285_0277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000553 Genomic DNA. Translation: ABM74835.1 .
RefSeqi WP_011823052.1. NC_008819.1.
YP_001014100.1. NC_008819.1.

3D structure databases

ProteinModelPortali A2C025.
SMRi A2C025. Positions 1-400.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 167555.NATL1_02711.

Proteomic databases

PRIDEi A2C025.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABM74835 ; ABM74835 ; NATL1_02711 .
GeneIDi 4779905.
KEGGi pme:NATL1_02711.
PATRICi 23018063. VBIProMar31285_0277.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi WEALDIG.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci PMAR167555:GI3K-275-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL1A.

Entry informationi

Entry nameiPGK_PROM1
AccessioniPrimary (citable) accession number: A2C025
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: February 20, 2007
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3