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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR167555:G1G7Z-242-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:NATL1_02621
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002592 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000180871 – 607Arginine--tRNA ligaseAdd BLAST607

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi167555.NATL1_02621

Structurei

3D structure databases

ProteinModelPortaliA2C016
SMRiA2C016
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi147 – 157"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247212
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.701 hit
3.40.50.6201 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A2C016-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEISARLEE ALNRAFTKVF PQEDRSSKTS SILTGSNLVP ASKPEFGDFQ
60 70 80 90 100
INCALSLAKE INRPPRDIAQ QIAKQLQQDN DFVRICNPPL IAGPGFINLS
110 120 130 140 150
INSKTLISEI HFRLNDKRLG VPLKKFNTDK IEEEKSNNRV IIDFSSPNIA
160 170 180 190 200
KEMHVGHLRS TIIGDSLARV LEFCGYEVLR LNHVGDWGTQ FGMLITHLKE
210 220 230 240 250
VVPEVLHTKD VVEISDLVNF YRQAKKRFDE DQIFQNKSRS EVVNLQAGDK
260 270 280 290 300
ESLIAWQLLC NQSRKEFQKI YDRLDIKLTE RGESFYNKFL VDVINDLKNK
310 320 330 340 350
KLLINDQGAQ CIFLDGLVGK DGKPQPIIIQ KSDGGFNYAT TDLAAIKYRL
360 370 380 390 400
TIPPHGDGAC RLIYVTDAGQ ASHFSGVFQI AKLANWIPTD CQIEHVPFGL
410 420 430 440 450
VQGEDGKKLK TRSGETIRLV DLLDEAIQRA RDDLKNRLNT ESRSENENFI
460 470 480 490 500
DKVSTTVGIA SIKYADLSQN RISNYQFSFD KMLSLQGNTA PYLLYALVRI
510 520 530 540 550
AGISRKGGDL NVSSQNIQFN ESQEWDLIRK LLQLDSIIAE VEKELLPNRL
560 570 580 590 600
CGYLFELSQT FNRFYDQVPI LKASEPSRAS RLVLCSITAD TLKLGMSLLG

IPTLERM
Length:607
Mass (Da):68,529
Last modified:February 20, 2007 - v1
Checksum:i2CAF8267062EDB13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000553 Genomic DNA Translation: ABM74826.1
RefSeqiWP_011823044.1, NC_008819.1

Genome annotation databases

EnsemblBacteriaiABM74826; ABM74826; NATL1_02621
KEGGipme:NATL1_02621

Similar proteinsi

Entry informationi

Entry nameiSYR_PROM1
AccessioniPrimary (citable) accession number: A2C016
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: February 28, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome