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Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Prochlorococcus marinus (strain NATL1A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. no protein annotated in this organism
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPMAR167555:G1G7Z-35-MONOMER
UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:NATL1_00341
OrganismiProchlorococcus marinus (strain NATL1A)
Taxonomic identifieri167555 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002592 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000468711 – 381Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST381

Interactioni

Protein-protein interaction databases

STRINGi167555.NATL1_00341

Structurei

3D structure databases

ProteinModelPortaliA2BZD8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107VQD Bacteria
COG1903 LUCA
HOGENOMiHOG000232408
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

A2BZD8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQFTLPVWV VAAAKSATNI LIGNKFRDKE RIDLPNKEES ISVPISSSAL
60 70 80 90 100
LDNGKRSLAV SHCQSGLPLD ITRGVEIWAY IQLSKGSSQS KGKVQNGFPD
110 120 130 140 150
WLDFHAGCGV GKFQSSGQPC ISQFARDLLC INLYPLVPKG NSIKVEIILP
160 170 180 190 200
EGKDRASKTS NEAFGVVDGL SLIGTQAEVQ ISASPDQLKN CKEILYHKCS
210 220 230 240 250
EAKFDGCLTF VIGENGMDLA MKYGLPANQI IKTGNWLGPL LVAAAENGVK
260 270 280 290 300
KLLLFGYHGK LIKLSGGVFH THHHLADGRI EILTSLAFRE GISFDLIELI
310 320 330 340 350
SKSTSVENAL LTLEVSNPDA VSLIWSRMAK EIEIKSRSYV NRYLSSSMEI
360 370 380
GSVLFDRKRQ MRWAGLEGLK QINSLGLILK R
Length:381
Mass (Da):41,729
Last modified:February 20, 2007 - v1
Checksum:i447ED318C4FC2679
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000553 Genomic DNA Translation: ABM74598.1
RefSeqiWP_011822836.1, NC_008819.1

Genome annotation databases

EnsemblBacteriaiABM74598; ABM74598; NATL1_00341
KEGGipme:NATL1_00341

Similar proteinsi

Entry informationi

Entry nameiCBID_PROM1
AccessioniPrimary (citable) accession number: A2BZD8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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