A2BVN1 (A2BVN1_PROM5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Dihydroorotase EMBL ABM71842.1
EC=3.5.2.3 EMBL ABM71842.1

Gene names

Ordered Locus Names:

P9515_06331

Organism

Prochlorococcus marinus (strain MIT 9515) [Complete proteome] [HAMAP] EMBL ABM71842.1

Taxonomic identifier

167542 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. SAAS SAAS004721
Cofactor	Binds 2 zinc ions per subunit By similarity. SAAS SAAS004721
Pathway	Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. SAAS SAAS004721
Subunit structure	Homodimer By similarity. SAAS SAAS004721

Ontologies

Keywords
Biological process	Pyrimidine biosynthesis SAAS SAAS004721
Ligand	Metal-binding SAAS SAAS004721 Zinc SAAS SAAS004721
Molecular function	Hydrolase SAAS SAAS004721 EMBL ABM71842.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pyrimidine base biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine nucleotide biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	dihydroorotase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A2BVN1 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: 270D322970F0784E	FASTA	349	39,690
	10 20 30 40 50 60 MKDLTILKPD DWHLHLREGI VLKNIIKFSS EFFGRAIVMP NTKNPITSIN KCISYKKSIS 70 80 90 100 110 120 EGLPENSKFE PLMTIYLTDE TIKDELIEGF KNDVFFAAKL YPANATTNSS QGVKKIENLY 130 140 150 160 170 180 EIFEVMEELG MPLLIHGEVT DPKVDIFDRE VVFIDKELLP LIQRFPKLKI VLEHITTSYA 190 200 210 220 230 240 VSFVQENNLG ATITPHHLHI NRNAMFFGGL NSDFYCLPVA KRENNRIALR KAATSGKKCF 250 260 270 280 290 300 FLGTDSAPHL RQWKAFCGCA GIFNSPVAIE SYIQVFDEED SLDQFEKFAS LNGPNFYNLP 310 320 330 340 VNKEKIRLVS KSNEIPKFIE VIDNNKVVGQ IKPFHAGEIL NWQVEGIVN

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000552 Genomic DNA. Translation: ABM71842.1.
RefSeq	YP_001010949.1. NC_008817.1.
3D structure databases
ProteinModelPortal	A2BVN1.
ModBase	Search...
Protein-protein interaction databases
STRING	A2BVN1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4719641.
GenomeReviews	Gene locus P9515_06331 in contig CP000552_GR.
KEGG	pmc:P9515_06331.
PATRIC	23014846. VBIProMar113831_0652.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0418.
HOGENOM	HBG628648.
OMA	CLPVAKR.
PhylomeDB	A2BVN1.
ProtClustDB	PRK05451.
Enzyme and pathway databases
BioCyc	PMAR167542:P9515ORF_0668-MONOMER.
Family and domain databases
InterPro	IPR006680. Amidohydro_1. IPR004721. DHOdimr. IPR002195. Dihydroorotase_CS. [Graphical view]
KO	K01465.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
PIRSF	PIRSF001237. DHOdimr. 1 hit.
TIGRFAMs	TIGR00856. PyrC_dimer. 1 hit.
PROSITE	PS00482. DIHYDROOROTASE_1. 1 hit. PS00483. DIHYDROOROTASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A2BVN1_PROM5

Accession

Primary (citable) accession number: A2BVN1

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)