A2BUR3 (A2BUR3_PROM5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Name:	fabI EMBL ABM71524.1
Ordered Locus Names:	P9515_03151

Organism

Prochlorococcus marinus (strain MIT 9515) [Complete proteome] [HAMAP] EMBL ABM71524.1

Taxonomic identifier

167542 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL ABM71524.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	159	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	A2BUR3 [UniParc]. Last modified February 20, 2007. Version 1. Checksum: FBE920CBAC9E7D7F	FASTA	260	27,790
	10 20 30 40 50 60 MLLNLTGKKI LVTGIANNRS IAWGIAQQLS KAGAELGITY LPDEKGRFES KVRELTKDLK 70 80 90 100 110 120 PSLFLPLDVQ NPSQIEEIFE NIKNNWGQID GLVHCLAFAG RDELIGDYSA TSSEGFDRAL 130 140 150 160 170 180 NISAYSLAPL CKAAKPLFSD GAGVVSLTYL GSERAIPNYN VMGVAKAALE ASVRYLSAEL 190 200 210 220 230 240 GPERQVRVNA ISAGPIRTLA SSAIGGILDM IHNVEEKAPL RRTVTQTEVG NTAAFLLSDL 250 260 ASGISGQTIY VDAGYCINGM

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000552 Genomic DNA. Translation: ABM71524.1.
RefSeq	YP_001010631.1. NC_008817.1.
3D structure databases
ProteinModelPortal	A2BUR3.
ModBase	Search...
Protein-protein interaction databases
STRING	A2BUR3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4718673.
GenomeReviews	Gene locus P9515_03151 in contig CP000552_GR.
KEGG	pmc:P9515_03151.
PATRIC	23014160. VBIProMar113831_0320.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
HOGENOM	HBG750976.
OMA	MILKWNE.
PhylomeDB	A2BUR3.
ProtClustDB	PRK07370.
Enzyme and pathway databases
BioCyc	PMAR167542:P9515ORF_0328-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

A2BUR3_PROM5

Accession

Primary (citable) accession number: A2BUR3

Entry history

Integrated into UniProtKB/TrEMBL:	February 20, 2007
Last sequence update:	February 20, 2007
Last modified:	December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)