Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

A2BU00

- SPEA_PROM5

UniProt

A2BU00 - SPEA_PROM5

Protein

Biosynthetic arginine decarboxylase

Gene

speA

Organism
Prochlorococcus marinus (strain MIT 9515)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (20 Feb 2007)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the biosynthesis of agmatine from arginine.UniRule annotation

    Catalytic activityi

    L-arginine = agmatine + CO2.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation
    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. arginine decarboxylase activity Source: UniProtKB-HAMAP
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. arginine catabolic process Source: InterPro
    2. spermidine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Polyamine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Magnesium, Metal-binding, Pyridoxal phosphate

    Enzyme and pathway databases

    BioCyciPMAR167542:GI3N-53-MONOMER.
    UniPathwayiUPA00186; UER00284.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Biosynthetic arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
    Short name:
    ADCUniRule annotation
    Gene namesi
    Name:speAUniRule annotation
    Ordered Locus Names:P9515_00521
    OrganismiProchlorococcus marinus (strain MIT 9515)
    Taxonomic identifieri167542 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
    ProteomesiUP000001589: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 648648Biosynthetic arginine decarboxylasePRO_1000024260Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei109 – 1091N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi167542.P9515_00521.

    Structurei

    3D structure databases

    ProteinModelPortaliA2BU00.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni291 – 30111Substrate-bindingUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1166.
    HOGENOMiHOG000029191.
    KOiK01585.
    OMAiIDHYVDG.
    OrthoDBiEOG676Z0R.

    Family and domain databases

    Gene3Di2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPiMF_01417. SpeA.
    InterProiIPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSiPR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR01273. speA. 1 hit.
    PROSITEiPS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A2BU00-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNFDSKKLN KHWTIEDSIS TYGIDKWGDQ YFSINSLGNI SITPNRNSKK    50
    TIDLFKLVNE IKSREINTPL ILRFNDILKD RITELNNAFS QAIETYNYKN 100
    IFQGVFPIKC NQQKNVLEKI IEYGDYWDFG LEVGSKSELL IGLSLLENKK 150
    SLLICNGYKD KKYIEIAILA RKLGKQPIIV IEQIDEVQRI IEAVKNLRST 200
    PILGIRSKLS SKSSGRWGKS VGDNSKFGLS IPEIMLTIKE LKEASLINEM 250
    KLLHFHIGSQ ISDISVIKDA LQEASQIFVE LSKLGAPMKY IDVGGGLGID 300
    FDGTKTSSNT STNYSLQNYA NDVVATIKDS CEVNNIQHPI IISESGRAIV 350
    SHCSVLIFDV LGTSHVSSQI KVSHQKKTSL IIKNLIDTHN QLKNLRNKKE 400
    DLSEIIELWN DAKKFKKDCL VAFRLGFISL GERAYAEELT WACAKEISSH 450
    LDNEKIIHPD LSEITETLSS TYYANLSVFK SIPDTWAINQ IFPIIPIHRH 500
    LEEPICKGNF ADLTCDSDGK LNNFIDNGKI KSLLNLHRPE ENNDYLIGIF 550
    MAGAYQEALG NFHNLFGNTN VIHIDINEDN TYKIKNIIKE NSKSEILELL 600
    DYSSDNLVES IRINTEFAIN NKTLSIEEAR KLIDQIETSL RKSSYLSE 648
    Length:648
    Mass (Da):73,324
    Last modified:February 20, 2007 - v1
    Checksum:iFAD4EF01EC8D33A4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000552 Genomic DNA. Translation: ABM71261.1.
    RefSeqiYP_001010368.1. NC_008817.1.

    Genome annotation databases

    EnsemblBacteriaiABM71261; ABM71261; P9515_00521.
    GeneIDi4719928.
    KEGGipmc:P9515_00521.
    PATRICi23013618. VBIProMar113831_0054.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000552 Genomic DNA. Translation: ABM71261.1 .
    RefSeqi YP_001010368.1. NC_008817.1.

    3D structure databases

    ProteinModelPortali A2BU00.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 167542.P9515_00521.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABM71261 ; ABM71261 ; P9515_00521 .
    GeneIDi 4719928.
    KEGGi pmc:P9515_00521.
    PATRICi 23013618. VBIProMar113831_0054.

    Phylogenomic databases

    eggNOGi COG1166.
    HOGENOMi HOG000029191.
    KOi K01585.
    OMAi IDHYVDG.
    OrthoDBi EOG676Z0R.

    Enzyme and pathway databases

    UniPathwayi UPA00186 ; UER00284 .
    BioCyci PMAR167542:GI3N-53-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPi MF_01417. SpeA.
    InterProi IPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022657. De-COase2_CS.
    IPR022644. De-COase2_N.
    IPR022653. De-COase2_pyr-phos_BS.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSi PR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR01273. speA. 1 hit.
    PROSITEi PS00878. ODR_DC_2_1. 1 hit.
    PS00879. ODR_DC_2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MIT 9515.

    Entry informationi

    Entry nameiSPEA_PROM5
    AccessioniPrimary (citable) accession number: A2BU00
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: February 20, 2007
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3