Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A2BTF4 (CAPP_PROMS) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:A9601_17821
OrganismProchlorococcus marinus (strain AS9601) [Complete proteome] [HAMAP]
Taxonomic identifier146891 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length989 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 989989Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_1000025573

Sites

Active site1751 By similarity
Active site6301 By similarity

Sequences

Sequence LengthMass (Da)Tools
A2BTF4 [UniParc].

Last modified February 20, 2007. Version 1.
Checksum: ED9923DAA5B08E37

FASTA989114,241
        10         20         30         40         50         60 
MESFRQVKNN NVDLISNNDP LDKNRLLIED LWESVLREEC PDDQAERLIQ LKELSYSKQI 

        70         80         90        100        110        120 
DGDSSKTFKN EIVDIVNSMD LAESIAAARA FSLYFQLVNI LEQRVEEDRY IQSFTNKDVQ 

       130        140        150        160        170        180 
KSPDNLDPFA PALARQNAPV TFRELFYRLR KLNVPPGKLE ELLQEMDIRL VFTAHPTEIV 

       190        200        210        220        230        240 
RHTIRHKQTR VANLLKKIQI EQFLTKEEKN SLKTQLKEEV RLWWRTDELH QFKPSVLDEV 

       250        260        270        280        290        300 
DYALHYFQQV LFNAMPQLRG RIAEALTDNY PDVQLPSESF CNFGSWVGSD RDGNPSVTPE 

       310        320        330        340        350        360 
ITWRTACYQR QLMLERYIIA TSNLRDQLSV SMQWSQVSSS LLESLETDRV KFPEIYEARA 

       370        380        390        400        410        420 
TRYRSEPYRL KLSYILEKLR LTQERNNLLA DSGWKFDLEG ETDNKNLDKV ESLYYKSVKE 

       430        440        450        460        470        480 
FTYDLELIKN SLISTDLNCE SVNTLLTQVH IFGFSLASLD IRQESTRHSD AIQELTNYLD 

       490        500        510        520        530        540 
LSVQYDQMSE EEKIKWLIDE LNTKRPLIPS DVHWTKTTEE TFSVFKMVKR LQQEFGSRIC 

       550        560        570        580        590        600 
HSYVISMSHS ASDLLEVLLL AKEMGLLDQN SQKSKLLVVP LFETVEDLKR APEVMEKLFK 

       610        620        630        640        650        660 
LDFYRSLLPK VGESFKPLQE LMLGYSDSNK DSGFVSSNWE IHRAQIALQN LSSRNNILLR 

       670        680        690        700        710        720 
LFHGRGGSVG RGGGPAYQAI LAQPSGTLKG RIKITEQGEV LASKYSLPEL ALYNLETVTT 

       730        740        750        760        770        780 
AVIQNSLVNN RLDATPEWNQ LMSRLAETSR SHYRKLVHEN PDLLNFFQEV TPIEEISKLQ 

       790        800        810        820        830        840 
ISSRPARRKK GAKDLSSLRA IPWVFGWTQS RFLLPSWFGV GTALSSELNL DPQQIELLRV 

       850        860        870        880        890        900 
LHQRWPFFRM LISKVEMTLS KVDLEVARYY VDTLGSKENK DSFDNIFEVI SKEYNLTKSL 

       910        920        930        940        950        960 
ILEITGKNKL LESDRDLKSS VSLRNKTIIP LGFLQVSLLR RLRDQTRQPP ISEFFLDKDE 

       970        980 
STRAYSRSEL LRGALLTING IAAGMRNTG 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AS9601.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000551 Genomic DNA. Translation: ABM71065.1.
RefSeqYP_001010172.1. NC_008816.1.

3D structure databases

ProteinModelPortalA2BTF4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING146891.A9601_17821.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABM71065; ABM71065; A9601_17821.
GeneID4718516.
KEGGpmb:A9601_17821.
PATRIC22985109. VBIProMar75723_1794.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAAIPWVFG.
OrthoDBEOG6TJ7T8.
ProtClustDBPRK00009.

Enzyme and pathway databases

BioCycPMAR146891:GH90-1817-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_PROMS
AccessionPrimary (citable) accession number: A2BTF4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: February 19, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families