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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Prochlorococcus marinus (strain AS9601)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei175 – 1751UniRule annotation
Active sitei630 – 6301UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciPMAR146891:GH90-1817-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:A9601_17821
OrganismiProchlorococcus marinus (strain AS9601)
Taxonomic identifieri146891 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002590: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 989989Phosphoenolpyruvate carboxylasePRO_1000025573Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi146891.A9601_17821.

Structurei

3D structure databases

ProteinModelPortaliA2BTF4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A2BTF4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESFRQVKNN NVDLISNNDP LDKNRLLIED LWESVLREEC PDDQAERLIQ
60 70 80 90 100
LKELSYSKQI DGDSSKTFKN EIVDIVNSMD LAESIAAARA FSLYFQLVNI
110 120 130 140 150
LEQRVEEDRY IQSFTNKDVQ KSPDNLDPFA PALARQNAPV TFRELFYRLR
160 170 180 190 200
KLNVPPGKLE ELLQEMDIRL VFTAHPTEIV RHTIRHKQTR VANLLKKIQI
210 220 230 240 250
EQFLTKEEKN SLKTQLKEEV RLWWRTDELH QFKPSVLDEV DYALHYFQQV
260 270 280 290 300
LFNAMPQLRG RIAEALTDNY PDVQLPSESF CNFGSWVGSD RDGNPSVTPE
310 320 330 340 350
ITWRTACYQR QLMLERYIIA TSNLRDQLSV SMQWSQVSSS LLESLETDRV
360 370 380 390 400
KFPEIYEARA TRYRSEPYRL KLSYILEKLR LTQERNNLLA DSGWKFDLEG
410 420 430 440 450
ETDNKNLDKV ESLYYKSVKE FTYDLELIKN SLISTDLNCE SVNTLLTQVH
460 470 480 490 500
IFGFSLASLD IRQESTRHSD AIQELTNYLD LSVQYDQMSE EEKIKWLIDE
510 520 530 540 550
LNTKRPLIPS DVHWTKTTEE TFSVFKMVKR LQQEFGSRIC HSYVISMSHS
560 570 580 590 600
ASDLLEVLLL AKEMGLLDQN SQKSKLLVVP LFETVEDLKR APEVMEKLFK
610 620 630 640 650
LDFYRSLLPK VGESFKPLQE LMLGYSDSNK DSGFVSSNWE IHRAQIALQN
660 670 680 690 700
LSSRNNILLR LFHGRGGSVG RGGGPAYQAI LAQPSGTLKG RIKITEQGEV
710 720 730 740 750
LASKYSLPEL ALYNLETVTT AVIQNSLVNN RLDATPEWNQ LMSRLAETSR
760 770 780 790 800
SHYRKLVHEN PDLLNFFQEV TPIEEISKLQ ISSRPARRKK GAKDLSSLRA
810 820 830 840 850
IPWVFGWTQS RFLLPSWFGV GTALSSELNL DPQQIELLRV LHQRWPFFRM
860 870 880 890 900
LISKVEMTLS KVDLEVARYY VDTLGSKENK DSFDNIFEVI SKEYNLTKSL
910 920 930 940 950
ILEITGKNKL LESDRDLKSS VSLRNKTIIP LGFLQVSLLR RLRDQTRQPP
960 970 980
ISEFFLDKDE STRAYSRSEL LRGALLTING IAAGMRNTG
Length:989
Mass (Da):114,241
Last modified:February 20, 2007 - v1
Checksum:iED9923DAA5B08E37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM71065.1.
RefSeqiWP_011819187.1. NC_008816.1.
YP_001010172.1. NC_008816.1.

Genome annotation databases

EnsemblBacteriaiABM71065; ABM71065; A9601_17821.
GeneIDi4718516.
KEGGipmb:A9601_17821.
PATRICi22985109. VBIProMar75723_1794.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000551 Genomic DNA. Translation: ABM71065.1.
RefSeqiWP_011819187.1. NC_008816.1.
YP_001010172.1. NC_008816.1.

3D structure databases

ProteinModelPortaliA2BTF4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi146891.A9601_17821.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABM71065; ABM71065; A9601_17821.
GeneIDi4718516.
KEGGipmb:A9601_17821.
PATRICi22985109. VBIProMar75723_1794.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciPMAR146891:GH90-1817-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AS9601.

Entry informationi

Entry nameiCAPP_PROMS
AccessioniPrimary (citable) accession number: A2BTF4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: February 20, 2007
Last modified: January 7, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.